diff --git a/CMakeExternals/PCRE.cmake b/CMakeExternals/PCRE.cmake
index c8a37b69c9..5a70f9b497 100644
--- a/CMakeExternals/PCRE.cmake
+++ b/CMakeExternals/PCRE.cmake
@@ -1,69 +1,69 @@
 #--------------------------------------------------------------------------
 #  PCRE (Perl Compatible Regular Expressions)
 #--------------------------------------------------------------------------
 if(MITK_USE_PCRE)
   if(DEFINED PCRE_DIR AND NOT EXISTS ${PCRE_DIR})
       message(FATAL_ERROR "PCRE_DIR variable is defined but corresponds to non-existing directory")
    endif()
 
   set(proj PCRE)
   set(${proj}_DEPENDENCIES "")
   set(${proj}_DEPENDS ${proj})
 
   if(NOT PCRE_DIR)
 
     if(UNIX)
       # Some other projects (e.g. Swig) require a pcre-config script which is not
       # generated when using the CMake build system.
       set(configure_cmd
         CONFIGURE_COMMAND <SOURCE_DIR>/./configure
         CC=${CMAKE_C_COMPILER}${CMAKE_C_COMPILER_ARG1}
         CFLAGS=-fPIC
         "CXXFLAGS=-fPIC ${MITK_CXX${MITK_CXX_STANDARD}_FLAG} ${CMAKE_CXX_FLAGS} ${CMAKE_CXX_FLAGS_RELEASE}"
         "LDFLAGS=${CMAKE_LINKER_FLAGS} ${CMAKE_LINKER_FLAGS_RELEASE} ${_install_rpath_linkflag}"
         CXX=${CMAKE_CXX_COMPILER}${CMAKE_CXX_COMPILER_ARG1}
         --prefix=<INSTALL_DIR>
         --disable-shared
         --enable-jit
       )
     else()
 
       set(additional_cmake_args )
       if(CTEST_USE_LAUNCHERS)
         list(APPEND additional_cmake_args
           "-DCMAKE_PROJECT_${proj}_INCLUDE:FILEPATH=${CMAKE_ROOT}/Modules/CTestUseLaunchers.cmake"
         )
       endif()
 
       set(configure_cmd
         CMAKE_GENERATOR ${gen}
         CMAKE_GENERATOR_PLATFORM ${gen_platform}
         CMAKE_ARGS
           ${ep_common_args}
           ${additional_cmake_args}
          "-DCMAKE_C_FLAGS:STRING=${CMAKE_C_FLAGS} -fPIC"
          -DBUILD_SHARED_LIBS:BOOL=OFF
          -DPCRE_BUILD_PCREGREP:BOOL=OFF
          -DPCRE_BUILD_TESTS:BOOL=OFF
          -DPCRE_SUPPORT_JIT:BOOL=ON
        CMAKE_CACHE_ARGS
          ${ep_common_cache_args}
        CMAKE_CACHE_DEFAULT_ARGS
          ${ep_common_cache_default_args}
       )
     endif()
 
     ExternalProject_add(${proj}
       LIST_SEPARATOR ${sep}
-      URL ${MITK_THIRDPARTY_DOWNLOAD_PREFIX_URL}/pcre-8.35.tar.gz
-      URL_MD5 "ed58bcbe54d3b1d59e9f5415ef45ce1c"
+      URL ${MITK_THIRDPARTY_DOWNLOAD_PREFIX_URL}/pcre-8.45.tar.gz
+      URL_MD5 "01b80f8177ab91da63e7e5c5d5dfcb83"
       ${configure_cmd}
       DEPENDS "${${proj}_DEPENDENCIES}"
       )
 
     set(PCRE_DIR ${ep_prefix})
 
   else()
     mitkMacroEmptyExternalProject(${proj} "${${proj}_DEPENDENCIES}")
   endif()
 endif()