diff --git a/CMakeExternals/ITK-4.11.0.patch b/CMakeExternals/ITK-4.11.0.patch
deleted file mode 100644
index 9a285c0804..0000000000
--- a/CMakeExternals/ITK-4.11.0.patch
+++ /dev/null
@@ -1,22 +0,0 @@
-diff --git a/Modules/ThirdParty/GDCM/CMakeLists.txt b/Modules/ThirdParty/GDCM/CMakeLists.txt
-index bf2d27d..e321215 100644
---- a/Modules/ThirdParty/GDCM/CMakeLists.txt
-+++ b/Modules/ThirdParty/GDCM/CMakeLists.txt
-@@ -4,7 +4,7 @@ set(ITKGDCM_THIRD_PARTY 1)
- if(ITK_USE_SYSTEM_GDCM)
-   set(ITKGDCM_SYSTEM_INCLUDE_DIRS ${GDCM_INCLUDE_DIRS})
-   set(ITKGDCM_SYSTEM_LIBRARY_DIRS ${GDCM_LIBRARY_DIRS})
--  set(ITKGDCM_LIBRARIES gdcmDICT gdcmMSFF)
-+  set(ITKGDCM_LIBRARIES gdcmDICT gdcmMSFF gdcmDSED)
-   set(ITKGDCM_NO_SRC 1)
- 
-   # When this module is loaded by an app, load GDCM too.
-@@ -42,7 +42,7 @@ else()
-       endif()
-     endif()
-   endif()
--  set(ITKGDCM_LIBRARIES  gdcmDICT gdcmMSFF )
-+  set(ITKGDCM_LIBRARIES  gdcmDICT gdcmMSFF gdcmDSED)
- endif()
- 
- itk_module_impl()
diff --git a/CMakeExternals/ITK.cmake b/CMakeExternals/ITK.cmake
index de97277bce..30e2acaf73 100644
--- a/CMakeExternals/ITK.cmake
+++ b/CMakeExternals/ITK.cmake
@@ -1,86 +1,86 @@
 #-----------------------------------------------------------------------------
 # ITK
 #-----------------------------------------------------------------------------
 
 # Sanity checks
 if(DEFINED ITK_DIR AND NOT EXISTS ${ITK_DIR})
   message(FATAL_ERROR "ITK_DIR variable is defined but corresponds to non-existing directory")
 endif()
 
 set(proj ITK)
 set(proj_DEPENDENCIES GDCM)
 
 if(MITK_USE_OpenCV)
   list(APPEND proj_DEPENDENCIES OpenCV)
 endif()
 
 if(MITK_USE_HDF5)
   list(APPEND proj_DEPENDENCIES HDF5)
 endif()
 
 set(ITK_DEPENDS ${proj})
 
 if(NOT DEFINED ITK_DIR)
 
   set(additional_cmake_args )
   if(MINGW)
     set(additional_cmake_args
         -DCMAKE_USE_WIN32_THREADS:BOOL=ON
         -DCMAKE_USE_PTHREADS:BOOL=OFF)
   endif()
 
   list(APPEND additional_cmake_args
        -DUSE_WRAP_ITK:BOOL=OFF
       )
 
   if(MITK_USE_OpenCV)
     list(APPEND additional_cmake_args
          -DModule_ITKVideoBridgeOpenCV:BOOL=ON
          -DOpenCV_DIR:PATH=${OpenCV_DIR}
         )
   endif()
 
   # Keep the behaviour of ITK 4.3 which by default turned on ITK Review
   # see MITK bug #17338
   list(APPEND additional_cmake_args
     -DModule_ITKReview:BOOL=ON
   # for 4.7, the OpenJPEG is needed by review but the variable must be set
     -DModule_ITKOpenJPEG:BOOL=ON
   )
 
   if(CTEST_USE_LAUNCHERS)
     list(APPEND additional_cmake_args
       "-DCMAKE_PROJECT_${proj}_INCLUDE:FILEPATH=${CMAKE_ROOT}/Modules/CTestUseLaunchers.cmake"
     )
   endif()
 
   ExternalProject_Add(${proj}
      LIST_SEPARATOR ${sep}
-     URL ${MITK_THIRDPARTY_DOWNLOAD_PREFIX_URL}/InsightToolkit-4.11.0.tar.gz
-     URL_MD5 1a71ae9d2f7b3140ac17e8bbb0602c8a
+     URL ${MITK_THIRDPARTY_DOWNLOAD_PREFIX_URL}/InsightToolkit-4.12.2.tar.xz
+     URL_MD5 cee6436c1341db3813a85955c281e6a9
      # work with external GDCM
-     PATCH_COMMAND ${PATCH_COMMAND} -N -p1 -i ${CMAKE_CURRENT_LIST_DIR}/ITK-4.11.0.patch
+     # PATCH_COMMAND ${PATCH_COMMAND} -N -p1 -i ${CMAKE_CURRENT_LIST_DIR}/ITK-4.11.0.patch
      CMAKE_GENERATOR ${gen}
      CMAKE_ARGS
        ${ep_common_args}
        ${additional_cmake_args}
        -DBUILD_EXAMPLES:BOOL=OFF
        -DITK_USE_SYSTEM_GDCM:BOOL=ON
        -DGDCM_DIR:PATH=${GDCM_DIR}
        -DITK_USE_SYSTEM_HDF5:BOOL=ON
        -DHDF5_DIR:PATH=${HDF5_DIR}
      CMAKE_CACHE_ARGS
        ${ep_common_cache_args}
      CMAKE_CACHE_DEFAULT_ARGS
        ${ep_common_cache_default_args}
      DEPENDS ${proj_DEPENDENCIES}
     )
 
   set(ITK_DIR ${ep_prefix})
   mitkFunctionInstallExternalCMakeProject(${proj})
 
 else()
 
   mitkMacroEmptyExternalProject(${proj} "${proj_DEPENDENCIES}")
 
 endif()