diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_10_20.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_10_20.xml
index 8b85cd7abf..ae19e71c63 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_10_20.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_10_20.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="50" image-columns="50" image-slices="25" numberOfGaussians="2" spacingX="1" spacingY="1" spacingZ="2" entireHotSpotInImage="1">
     <gaussian centerIndexX="17" centerIndexY="7" centerIndexZ="7" deviationX="3" deviationY="5" deviationZ="4" altitude="10"/>
     <gaussian centerIndexX="44" centerIndexY="39" centerIndexZ="20" deviationX="6" deviationY="8" deviationZ="4" altitude="14"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="30" minimumSizeX="10" maximumSizeY="30" minimumSizeY="0" maximumSizeZ="25" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="30" minimumIndexX="10" maximumIndexY="30" minimumIndexY="0" maximumIndexZ="25" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="17" hotspotIndexY="7" hotspotIndexZ="7" mean="5.67591" maximumIndexX="17" maximumIndexY="7" maximumIndexZ="7" maximum="9.91183" minimumIndexX="11" minimumIndexY="6" minimumIndexZ="7" minimum="1.33906"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_40_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_40_30.xml
index e9231ddd79..a27278818b 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_40_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/GlobalPeakOutsideSegmentation_40_30.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="13" image-columns="13" image-slices="17" numberOfGaussians="2" spacingX="4" spacingY="4" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="2" centerIndexY="4" centerIndexZ="2" deviationX="4" deviationY="6" deviationZ="9" altitude="12"/>
     <gaussian centerIndexX="10" centerIndexY="12" centerIndexZ="15" deviationX="4" deviationY="7" deviationZ="9" altitude="16"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="6" minimumSizeX="0" maximumSizeY="13" minimumSizeY="0" maximumSizeZ="17" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="6" minimumIndexX="0" maximumIndexY="13" minimumIndexY="0" maximumIndexZ="17" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="2" hotspotIndexY="4" hotspotIndexZ="2" mean="12.0961" maximumIndexX="2" maximumIndexY="4" maximumIndexZ="2" maximum="12.3489" minimumIndexX="1" minimumIndexY="3" minimumIndexZ="2" minimum="11.6222"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_10_20.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_10_20.xml
index 99e0167486..df5300c886 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_10_20.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_10_20.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="50" image-columns="50" image-slices="25" numberOfGaussians="2" spacingX="1" spacingY="1" spacingZ="2" entireHotSpotInImage="1">
     <gaussian centerIndexX="7" centerIndexY="7" centerIndexZ="7" deviationX="3" deviationY="5" deviationZ="9" altitude="13"/>
     <gaussian centerIndexX="44" centerIndexY="39" centerIndexZ="20" deviationX="1" deviationY="2" deviationZ="2" altitude="14"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="50" minimumSizeX="0" maximumSizeY="50" minimumSizeY="0" maximumSizeZ="25" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="50" minimumIndexX="0" maximumIndexY="50" minimumIndexY="0" maximumIndexZ="25" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="7" hotspotIndexY="7" hotspotIndexZ="7" mean="7.7824" maximumIndexX="7" maximumIndexY="7" maximumIndexZ="7" maximum="12.9113" minimumIndexX="1" minimumIndexY="6" minimumIndexZ="7" minimum="1.74428"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_25_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_25_30.xml
index c03ada41c7..9e6fa1c8f4 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_25_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_25_30.xml
@@ -1,11 +1,11 @@
 <testcase>
   <testimage image-rows="20" image-columns="20" image-slices="17" numberOfGaussians="3" spacingX="2.5" spacingY="2.5" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="4" centerIndexY="3" centerIndexZ="4" deviationX="8" deviationY="4" deviationZ="9" altitude="15"/>
     <gaussian centerIndexX="6" centerIndexY="9" centerIndexZ="7" deviationX="3" deviationY="2" deviationZ="7" altitude="1"/>
     <gaussian centerIndexX="18" centerIndexY="16" centerIndexZ="15" deviationX="1" deviationY="2" deviationZ="2" altitude="17"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="20" minimumSizeX="0" maximumSizeY="20" minimumSizeY="0" maximumSizeZ="17" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="20" minimumIndexX="0" maximumIndexY="20" minimumIndexY="0" maximumIndexZ="17" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="4" hotspotIndexY="3" hotspotIndexZ="4" mean="14.2404" maximumIndexX="4" maximumIndexY="3" maximumIndexZ="4" maximum="14.9507" minimumIndexX="3" minimumIndexY="1" minimumIndexZ="4" minimum="13.0939"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_40_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_40_30.xml
index 199c39f30f..09aa3fadc3 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_40_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/MaxOutsidePeak_40_30.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="13" image-columns="13" image-slices="17" numberOfGaussians="2" spacingX="4" spacingY="4" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="2" centerIndexY="2" centerIndexZ="14" deviationX="4" deviationY="6" deviationZ="9" altitude="15"/>
     <gaussian centerIndexX="10" centerIndexY="10" centerIndexZ="15" deviationX="1" deviationY="2" deviationZ="1" altitude="16"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="13" minimumSizeX="0" maximumSizeY="13" minimumSizeY="0" maximumSizeZ="17" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="13" minimumIndexX="0" maximumIndexY="13" minimumIndexY="0" maximumIndexZ="17" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="2" hotspotIndexY="2" hotspotIndexZ="14" mean="14.5969" maximumIndexX="2" maximumIndexY="2" maximumIndexZ="14" maximum="14.9359" minimumIndexX="1" minimumIndexY="1" minimumIndexZ="14" minimum="14.2796"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_10_20.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_10_20.xml
index cce013e12e..acdf3d3b11 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_10_20.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_10_20.xml
@@ -1,9 +1,9 @@
 <testcase>
   <testimage image-rows="50" image-columns="50" image-slices="25" numberOfGaussians="1" spacingX="1" spacingY="1" spacingZ="2" entireHotSpotInImage="1">
     <gaussian centerIndexX="22" centerIndexY="21" centerIndexZ="21" deviationX="5" deviationY="12" deviationZ="9" altitude="15"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="20" minimumSizeX="0" maximumSizeY="20" minimumSizeY="0" maximumSizeZ="20" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="20" minimumIndexX="0" maximumIndexY="20" minimumIndexY="0" maximumIndexZ="20" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="20" hotspotIndexY="20" hotspotIndexZ="20" mean="11.6671" maximumIndexX="22" maximumIndexY="21" maximumIndexZ="21" maximum="14.9607" minimumIndexX="14" minimumIndexY="19" minimumIndexZ="20" minimum="4.09463"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_25_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_25_30.xml
index 74cc73aab8..df12f187ac 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_25_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_25_30.xml
@@ -1,11 +1,11 @@
 <testcase>
   <testimage image-rows="20" image-columns="20" image-slices="17" numberOfGaussians="3" spacingX="2.5" spacingY="2.5" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="10" centerIndexY="10" centerIndexZ="10" deviationX="8" deviationY="4" deviationZ="6" altitude="18"/>
     <gaussian centerIndexX="3" centerIndexY="4" centerIndexZ="2" deviationX="9" deviationY="5" deviationZ="6" altitude="3"/>
     <gaussian centerIndexX="16" centerIndexY="17" centerIndexZ="13" deviationX="3" deviationY="7" deviationZ="6" altitude="1"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="10" minimumSizeX="0" maximumSizeY="10" minimumSizeY="0" maximumSizeZ="10" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="10" minimumIndexX="0" maximumIndexY="10" minimumIndexY="0" maximumIndexZ="10" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="10" hotspotIndexY="10" hotspotIndexZ="10" mean="17.4882" maximumIndexX="10" maximumIndexY="10" maximumIndexZ="10" maximum="18.4372" minimumIndexX="10" minimumIndexY="12" minimumIndexZ="11" minimum="15.9072"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_40_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_40_30.xml
index 50ab0588b9..0440a5ecb6 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_40_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakInMaxOutsideSegmentation_40_30.xml
@@ -1,9 +1,9 @@
 <testcase>
   <testimage image-rows="13" image-columns="13" image-slices="17" numberOfGaussians="1" spacingX="4" spacingY="4" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="6" centerIndexY="6" centerIndexZ="5" deviationX="4" deviationY="6" deviationZ="9" altitude="12"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="6" minimumSizeX="0" maximumSizeY="6" minimumSizeY="0" maximumSizeZ="6" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="6" minimumIndexX="0" maximumIndexY="6" minimumIndexY="0" maximumIndexZ="6" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="6" hotspotIndexY="6" hotspotIndexZ="5" mean="11.6775" maximumIndexX="6" maximumIndexY="6" maximumIndexZ="5" maximum="11.9487" minimumIndexX="5" minimumIndexY="5" minimumIndexZ="5" minimum="11.4237"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_10_20.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_10_20.xml
index 8d7f4f6c56..2c2345627c 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_10_20.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_10_20.xml
@@ -1,12 +1,12 @@
 <testcase>
   <testimage image-rows="50" image-columns="50" image-slices="25" numberOfGaussians="4" spacingX="1" spacingY="1" spacingZ="2" entireHotSpotInImage="1">
     <gaussian centerIndexX="1" centerIndexY="1" centerIndexZ="2" deviationX="8" deviationY="9" deviationZ="6" altitude="17"/>
     <gaussian centerIndexX="22" centerIndexY="30" centerIndexZ="17" deviationX="6" deviationY="16" deviationZ="17" altitude="4"/>
     <gaussian centerIndexX="13" centerIndexY="8" centerIndexZ="9" deviationX="3" deviationY="5" deviationZ="4" altitude="2"/>
     <gaussian centerIndexX="18" centerIndexY="30" centerIndexZ="26" deviationX="4" deviationY="2" deviationZ="3" altitude="5"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="50" minimumSizeX="0" maximumSizeY="50" minimumSizeY="0" maximumSizeZ="25" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="50" minimumIndexX="0" maximumIndexY="50" minimumIndexY="0" maximumIndexZ="25" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="6" hotspotIndexY="6" hotspotIndexZ="3" mean="10.8607" maximumIndexX="2" maximumIndexY="2" maximumIndexZ="2" maximum="16.7283" minimumIndexX="9" minimumIndexY="11" minimumIndexZ="4" minimum="5.71475"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_25_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_25_30.xml
index d2e77e8eb1..4200ead9a2 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_25_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_25_30.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="20" image-columns="20" image-slices="17" numberOfGaussians="2" spacingX="2.5" spacingY="2.5" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="1" centerIndexY="5" centerIndexZ="1" deviationX="8" deviationY="4" deviationZ="6" altitude="17"/>
     <gaussian centerIndexX="14" centerIndexY="16" centerIndexZ="15" deviationX="6" deviationY="5" deviationZ="6" altitude="7"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="20" minimumSizeX="0" maximumSizeY="20" minimumSizeY="0" maximumSizeZ="17" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="20" minimumIndexX="0" maximumIndexY="20" minimumIndexY="0" maximumIndexZ="17" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="2" hotspotIndexY="5" hotspotIndexZ="2" mean="15.6619" maximumIndexX="1" maximumIndexY="5" maximumIndexZ="1" maximum="16.9279" minimumIndexX="2" minimumIndexY="3" minimumIndexZ="3" minimum="14.0348"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_40_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_40_30.xml
index ba2cf59f35..224c52e4d9 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_40_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/PeakNearBorder_40_30.xml
@@ -1,10 +1,10 @@
 <testcase>
   <testimage image-rows="13" image-columns="13" image-slices="17" numberOfGaussians="2" spacingX="4" spacingY="4" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="1" centerIndexY="2" centerIndexZ="1" deviationX="4" deviationY="6" deviationZ="9" altitude="17"/>
     <gaussian centerIndexX="10" centerIndexY="2" centerIndexZ="16" deviationX="4" deviationY="7" deviationZ="9" altitude="5"/>
   </testimage>
   <segmentation numberOfLabels="1" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="13" minimumSizeX="0" maximumSizeY="13" minimumSizeY="0" maximumSizeZ="17" minimumSizeZ="0"/>
+    <roi label="1" maximumIndexX="13" minimumIndexX="0" maximumIndexY="13" minimumIndexY="0" maximumIndexZ="17" minimumIndexZ="0"/>
   </segmentation>
   <statistic hotspotIndexX="2" hotspotIndexY="2" hotspotIndexZ="2" mean="16.1619" maximumIndexX="1" maximumIndexY="2" maximumIndexZ="1" maximum="17.0276" minimumIndexX="3" minimumIndexY="2" minimumIndexZ="3" minimum="14.9666"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_10_20.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_10_20.xml
index c8c308a82f..44d38d211f 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_10_20.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_10_20.xml
@@ -1,13 +1,13 @@
 <testcase>
   <testimage image-rows="50" image-columns="50" image-slices="25" numberOfGaussians="3" spacingX="1" spacingY="1" spacingZ="2" entireHotSpotInImage="1">
     <gaussian centerIndexX="22" centerIndexY="21" centerIndexZ="21" deviationX="5" deviationY="12" deviationZ="9" altitude="15"/>
     <gaussian centerIndexX="14" centerIndexY="4" centerIndexZ="15" deviationX="3" deviationY="17" deviationZ="3" altitude="10"/>
     <gaussian centerIndexX="2" centerIndexY="15" centerIndexZ="23" deviationX="8" deviationY="3" deviationZ="9" altitude="7"/>
   </testimage>
   <segmentation numberOfLabels="2" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="20" minimumSizeX="0" maximumSizeY="20" minimumSizeY="0" maximumSizeZ="10" minimumSizeZ="0"/>
-    <roi label="2" maximumSizeX="50" minimumSizeX="22" maximumSizeY="50" minimumSizeY="22" maximumSizeZ="25" minimumSizeZ="12"/>
+    <roi label="1" maximumIndexX="20" minimumIndexX="0" maximumIndexY="20" minimumIndexY="0" maximumIndexZ="10" minimumIndexZ="0"/>
+    <roi label="2" maximumIndexX="50" minimumIndexX="22" maximumIndexY="50" minimumIndexY="22" maximumIndexZ="25" minimumIndexZ="12"/>
   </segmentation>
   <statistic hotspotIndexX="20" hotspotIndexY="20" hotspotIndexZ="10" mean="6.23992" maximumIndexX="21" maximumIndexY="20" maximumIndexZ="13" maximum="10.251" minimumIndexX="16" minimumIndexY="22" minimumIndexZ="8" minimum="2.89693"/>
   <statistic hotspotIndexX="22" hotspotIndexY="22" hotspotIndexZ="21" mean="12.6261" maximumIndexX="22" maximumIndexY="21" maximumIndexZ="21" maximum="15.0264" minimumIndexX="28" minimumIndexY="23" minimumIndexZ="21" minimum="7.20183"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_25_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_25_30.xml
index 2a546d2e2a..d9121d7f24 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_25_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_25_30.xml
@@ -1,13 +1,13 @@
 <testcase>
   <testimage image-rows="20" image-columns="20" image-slices="17" numberOfGaussians="3" spacingX="2.5" spacingY="2.5" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="10" centerIndexY="10" centerIndexZ="4" deviationX="6" deviationY="3" deviationZ="4" altitude="18"/>
     <gaussian centerIndexX="4" centerIndexY="4" centerIndexZ="2" deviationX="9" deviationY="5" deviationZ="6" altitude="14"/>
     <gaussian centerIndexX="15" centerIndexY="17" centerIndexZ="13" deviationX="2" deviationY="5" deviationZ="6" altitude="13"/>
   </testimage>
   <segmentation numberOfLabels="2" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="10" minimumSizeX="0" maximumSizeY="10" minimumSizeY="0" maximumSizeZ="10" minimumSizeZ="0"/>
-    <roi label="2" maximumSizeX="20" minimumSizeX="15" maximumSizeY="20" minimumSizeY="15" maximumSizeZ="17" minimumSizeZ="12"/>
+    <roi label="1" maximumIndexX="10" minimumIndexX="0" maximumIndexY="10" minimumIndexY="0" maximumIndexZ="10" minimumIndexZ="0"/>
+    <roi label="2" maximumIndexX="20" minimumIndexX="15" maximumIndexY="20" minimumIndexY="15" maximumIndexZ="17" minimumIndexZ="12"/>
   </segmentation>
   <statistic hotspotIndexX="9" hotspotIndexY="9" hotspotIndexZ="4" mean="21.9441" maximumIndexX="9" maximumIndexY="9" maximumIndexZ="4" maximum="23.5511" minimumIndexX="9" minimumIndexY="7" minimumIndexZ="5" minimum="19.2318"/>
   <statistic hotspotIndexX="15" hotspotIndexY="17" hotspotIndexZ="13" mean="10.9936" maximumIndexX="15" maximumIndexY="17" maximumIndexZ="13" maximum="12.9419" minimumIndexX="17" minimumIndexY="18" minimumIndexZ="13" minimum="7.74678"/>
 </testcase>
diff --git a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_40_30.xml b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_40_30.xml
index 9a3c34693a..15d45e0420 100644
--- a/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_40_30.xml
+++ b/Modules/ImageStatistics/Testing/Data/Hotspot/TwoSegmentations_40_30.xml
@@ -1,12 +1,12 @@
 <testcase>
   <testimage image-rows="13" image-columns="13" image-slices="17" numberOfGaussians="2" spacingX="4" spacingY="4" spacingZ="3" entireHotSpotInImage="1">
     <gaussian centerIndexX="6" centerIndexY="6" centerIndexZ="5" deviationX="4" deviationY="6" deviationZ="9" altitude="12"/>
     <gaussian centerIndexX="12" centerIndexY="8" centerIndexZ="11" deviationX="3" deviationY="5" deviationZ="7" altitude="18"/>
   </testimage>
   <segmentation numberOfLabels="2" hotspotRadiusInMM="6.2035">
-    <roi label="1" maximumSizeX="6" minimumSizeX="0" maximumSizeY="6" minimumSizeY="0" maximumSizeZ="6" minimumSizeZ="0"/>
-    <roi label="2" maximumSizeX="13" minimumSizeX="8" maximumSizeY="13" minimumSizeY="8" maximumSizeZ="15" minimumSizeZ="8"/>
+    <roi label="1" maximumIndexX="6" minimumIndexX="0" maximumIndexY="6" minimumIndexY="0" maximumIndexZ="6" minimumIndexZ="0"/>
+    <roi label="2" maximumIndexX="13" minimumIndexX="8" maximumIndexY="13" minimumIndexY="8" maximumIndexZ="15" minimumIndexZ="8"/>
   </segmentation>
   <statistic hotspotIndexX="6" hotspotIndexY="6" hotspotIndexZ="6" mean="13.4651" maximumIndexX="7" maximumIndexY="6" maximumIndexZ="7" maximum="14.8425" minimumIndexX="5" minimumIndexY="5" minimumIndexZ="6" minimum="12.1336"/>
   <statistic hotspotIndexX="10" hotspotIndexY="8" hotspotIndexZ="10" mean="19.6405" maximumIndexX="11" maximumIndexY="8" maximumIndexZ="10" maximum="21.2001" minimumIndexX="9" minimumIndexY="9" minimumIndexZ="10" minimum="17.4011"/>
 </testcase>