diff --git a/Modules/Chart/CMakeLists.txt b/Modules/Chart/CMakeLists.txt
index ef1102c255..102806e36d 100644
--- a/Modules/Chart/CMakeLists.txt
+++ b/Modules/Chart/CMakeLists.txt
@@ -1,9 +1,4 @@
-SET (CHART_QT_MINIMUM_VERSION 5.10.0)
-IF (Qt5WebEngineWidgets_VERSION VERSION_LESS CHART_QT_MINIMUM_VERSION)
-  MESSAGE(AUTHOR_WARNING "MitkChart module requires at least ${CHART_QT_MINIMUM_VERSION}. Install this Qt version or above if you want to use MitkChart with full functionality.")
-ENDIF()
-
 MITK_CREATE_MODULE(
   DEPENDS MitkCore
   PACKAGE_DEPENDS PRIVATE Qt5|WebEngineWidgets
 )
diff --git a/Modules/Chart/include/QmitkChartWidget.h b/Modules/Chart/include/QmitkChartWidget.h
index 6eed0726a3..648181df9f 100644
--- a/Modules/Chart/include/QmitkChartWidget.h
+++ b/Modules/Chart/include/QmitkChartWidget.h
@@ -1,219 +1,218 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 #ifndef QmitkC3jsWidget_h
 #define QmitkC3jsWidget_h
 
 #include <map>
 #include <memory>
 #include <QWidget>
 
 #include <MitkChartExports.h>
 
 
 /*!
 \brief QmitkChartWidget is a widget to display various charts based on the javascript chart library C3js.
 * \details Data is added via AddData1D() or AddData2D().\n
 * There can be multiple charts (of different types with different properties) created by calling AddData1D or AddData2D multiple times.\n\n
 * The following chart types are supported:
 * * line chart: http://c3js.org/samples/simple_multiple.html
 * * bar chart: http://c3js.org/samples/chart_bar.html
 * * spline chart: http://c3js.org/samples/chart_spline.html
 * * pie chart: http://c3js.org/samples/chart_pie.html
 * * scatter chart: http://c3js.org/samples/chart_scatter.html
 * * area chart: http://c3js.org/samples/chart_area.html
 * * area spline chart: http://c3js.org/samples/chart_area.html
 *
 * Technical details: The javascript code is embedded in a QWebEngineView. The actual js code is implemented in resource\Chart.js.
 * \sa http://c3js.org for further information about the used javaScript library.
-* \warning We had issues with Qt versions <5.10. So we highly encourage to use Qt 5.10 or newer if this module is used.
 * \ingroup Modules/Chart
 */
 class MITKCHART_EXPORT QmitkChartWidget : public QWidget
 {
   Q_OBJECT
 
 public:
   /*!
   * \brief enum of diagram types.
   */
-	enum class ChartType { 
+  enum class ChartType {
     bar, /*!< bar chart, see http://c3js.org/samples/chart_bar.html */
     line, /*!< line chart, see http://c3js.org/samples/simple_multiple.html */
     spline, /*!< spline chart (smoothed line chart), see http://c3js.org/samples/chart_spline.html */
     pie, /*!< pie chart, see http://c3js.org/samples/chart_pie.html*/
     area, /*!< area chart, see http://c3js.org/samples/chart_area.html*/
     area_spline, /*!< area-spline chart, see http://c3js.org/samples/chart_area.html*/
     scatter /*!< scatter chart, see http://c3js.org/samples/chart_scatter.html*/
   };
   /*!
   * \brief enum of chart style (modifies background and line color).
   */
   enum class ChartStyle {
     darkstyle, /*!< background color: dark gray, line color: blue */
     lightstyle /*!< background color: white, line color: blue */
   };
   enum class LineStyle {
     solid,
     dashed
   };
   enum class AxisScale {
     linear,
     log
   };
 
   /*!
   * \brief enum of legend position.
   * See http://c3js.org/reference.html#legend-position
   */
   enum class LegendPosition {
     bottom,
     right,
     inset
   };
 
   explicit QmitkChartWidget(QWidget* parent = nullptr);
   ~QmitkChartWidget() override;
 
   /*!
   * \brief Adds 1D data to the widget
   * \details internally, the list is converted to a map with increasing integers keys starting at 0.
   * \param label the name of the data that is also used as identifier.
   * \param chartType the chart type that should be used for this data entry
   * \note the data can be cleared with ClearDiagram()
   * \note If the label name already exists, the name is replaced with a unique one by concatenating numbers to it.
   * \warning Pie chart is significantly different than the other chart types. Here, the data given by AddData1D is summed. Each entry represents a different category.
   */
   void AddData1D(const std::vector<double>& data1D, const std::string& label, ChartType chartType = ChartType::bar);
 
   /*!
   * \brief Adds 2D data to the widget. Call repeatedly for displaying multiple charts.
   * \details each entry represents a data point: key: value --> x-value: y-value.
   * \param label the name of the data that is also used as identifier.
   * \param chartType the chart type that should be used for this data entry
-  * \note the data can be cleared with ClearDiagram() 
+  * \note the data can be cleared with ClearDiagram()
   * \note If the label name already exists, the name is replaced with a unique one by concatenating numbers to it.
   * \warning Pie chart is significantly different than the other chart types. Here, the data given by AddData1D is summed. Each entry represents a different category.
   */
   void AddData2D(const std::map<double, double>& data2D, const std::string& label, ChartType chartType = ChartType::bar);
 
   /*!
   * \brief Removes data from the widget, works for 1D and 2D Data
   * \param label the name of the data that is also used as identifier.
   * \note All data can be cleared with ClearDiagram()
   * \throws Invalid Argument Exception when the label cannot be found
   */
   void RemoveData(const std::string& label);
 
   /*!
   * \brief Sets the color of one data entry (identifier is previously assigned label)
   * \details the color name can be "red" or a hex number (#FF0000).
   * \warning Either define all data entries with a color or no data entry. If a mixed approach is used,
   * C3 choses the color of the data entry (that could be the same as a user defined color).
   * \note If an unknown label is given, nothing happens.
   *  \sa https://www.w3schools.com/cssref/css_colors.asp
   */
   void SetColor(const std::string& label, const std::string& colorName);
 
   /*!
   * \brief Sets the line style of one data entry (identifier is previously assigned label)
   * \details two line styles are possible: LineStyle::solid and LineStyle::dashed.
   * The default line style is solid.
   * \note If an unknown label is given, nothing happens.
   *  \warning only sets the line style if the current chart type is ChartType::line.
   *  However, the line style remains also if the chart changes (e.g. new chart type)
   */
   void SetLineStyle(const std::string& label, LineStyle style);
 
   /*!
   * \brief Sets the axis scale to either linear (default) or logarithmic.
   */
   void SetYAxisScale(AxisScale scale);
 
   void SetXAxisLabel(const std::string& label);
 
   void SetYAxisLabel(const std::string& label);
 
   /*!
   * \brief Sets a title for the chart.
   */
   void SetTitle(const std::string &title);
 
   /*!
   * \brief Changes the chart type for all data entries and reloads the chart
   */
   void SetChartTypeForAllDataAndReload(ChartType type);
   /*!
   * \brief Sets the chart type for a data entry
   * \details for available types, see ChartType
   * \note If an unknown label is given, nothing happens.
   * \warning Pie chart is significantly different than the other chart types. Here, the data given by AddData1D is summed. Each entry represents a different category.
   * \sa DiagramType for available types
   */
   void SetChartType(const std::string& label, ChartType type);
 
   /*!
   * \brief Sets the legend position.
   * \details Default position is bottom.
   * \sa LegendPosition for available types
   */
   void SetLegendPosition(LegendPosition position);
 
   void SetShowLegend(bool show);
 
   /*!
   * \brief Displays the chart in the widget
   * \param showSubChart if a subchart is displayed inside the widget or not (see http://c3js.org/samples/options_subchart.html).
   * \exception if no data has been provided (\sa AddData1D AddData2D)
   */
   void Show(bool showSubChart=false);
 
   /*!
   * \brief Either displays the dataPoints or not
   * \param showDataPoints if dataPoints are displayed inside the widget or not.
   * \details: example for not showing points: http://c3js.org/samples/point_show.html
   * example for showing the points: http://c3js.org/samples/simple_multiple.html
   */
   void SetShowDataPoints(bool showDataPoints);
 
   /*!
   * \brief Clears all data inside and resets the widget.
   */
   void Clear();
 
   /*!
   * \brief Changes the theme of the widget.
   */
   void SetTheme(ChartStyle themeEnabled);
 
   /*!
   * \brief Reloads the chart in the widget
   * \details reloading may be needed to display added data in an existing chart
   * \param showSubChart if a subchart is displayed inside the widget or not.
   */
   void Reload(bool showSubChart);
 
 public slots:
   void OnLoadFinished(bool isLoadSuccessful);
 
 signals:
   void PageSuccessfullyLoaded();
 
 private:
   class Impl;
   std::unique_ptr<Impl> m_Impl;
 };
 
 #endif
diff --git a/Modules/Chart/src/QmitkChartWidget.cpp b/Modules/Chart/src/QmitkChartWidget.cpp
index 40372dc85b..63eba0a440 100644
--- a/Modules/Chart/src/QmitkChartWidget.cpp
+++ b/Modules/Chart/src/QmitkChartWidget.cpp
@@ -1,498 +1,494 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include <regex>
 
 #include <QmitkChartWidget.h>
 #include <QGridLayout>
 #include <QWebChannel>
 #include <QWebEngineView>
-#if QT_VERSION >= QT_VERSION_CHECK(5, 8, 0)
-  #include <QWebEngineSettings>
-#endif
+#include <QWebEngineSettings>
 
 #include <QmitkChartData.h>
 #include <QmitkChartxyData.h>
 #include "mitkExceptionMacro.h"
 
 class QmitkChartWidget::Impl final
 {
 public:
   explicit Impl(QWidget* parent);
   ~Impl();
 
   Impl(const Impl&) = delete;
   Impl& operator=(const Impl&) = delete;
 
   void AddData1D(const std::vector<double>& data1D, const std::string& label, QmitkChartWidget::ChartType chartType);
   void AddData2D(const std::map<double, double>& data2D, const std::string& label, QmitkChartWidget::ChartType chartType);
 
   void RemoveData(const std::string& label);
 
   void ClearData();
 
   void SetColor(const std::string& label, const std::string& colorName);
   void SetLineStyle(const std::string& label, LineStyle style);
 
   void SetYAxisScale(AxisScale scale);
 
   void SetXAxisLabel(const std::string& label);
 
   void SetYAxisLabel(const std::string& label);
 
   void SetTitle(const std::string &title);
 
   void SetLegendPosition(LegendPosition position);
 
   void SetShowLegend(bool show);
 
   void SetShowDataPoints(bool showDataPoints = false);
 
   void Show(bool showSubChart);
 
   void SetChartType(QmitkChartWidget::ChartType chartType);
   void SetChartTypeByLabel(const std::string& label, QmitkChartWidget::ChartType chartType);
 
   std::string ConvertChartTypeToString(QmitkChartWidget::ChartType chartType) const;
 
   void ClearJavaScriptChart();
   void InitializeJavaScriptChart();
   void CallJavaScriptFuntion(const QString& command);
 
 private:
 
   using ChartxyDataVector = std::vector<std::unique_ptr<QmitkChartxyData>>;
   std::string GetUniqueLabelName(const QList<QVariant>& labelList, const std::string& label) const;
   QmitkChartxyData* GetDataElementByLabel(const std::string& label) const;
   QList<QVariant> GetDataLabels(const ChartxyDataVector& c3xyData) const;
 
   QWebChannel* m_WebChannel;
   QWebEngineView* m_WebEngineView;
 
   QmitkChartData m_C3Data;
   ChartxyDataVector m_C3xyData;
   std::map<QmitkChartWidget::ChartType, std::string> m_ChartTypeToName;
   std::map<QmitkChartWidget::LegendPosition, std::string> m_LegendPositionToName;
   std::map<QmitkChartWidget::LineStyle, std::string> m_LineStyleToName;
   std::map<QmitkChartWidget::AxisScale, std::string> m_AxisScaleToName;
 };
 
 QmitkChartWidget::Impl::Impl(QWidget* parent)
   : m_WebChannel(new QWebChannel(parent))
   , m_WebEngineView(new QWebEngineView(parent))
 {
   //disable context menu for QWebEngineView
   m_WebEngineView->setContextMenuPolicy(Qt::NoContextMenu);
 
   //Set the webengineview to an initial empty page. The actual chart will be loaded once the data is calculated.
   m_WebEngineView->setUrl(QUrl(QStringLiteral("qrc:///C3js/empty.html")));
   m_WebEngineView->page()->setWebChannel(m_WebChannel);
-  #if QT_VERSION >= QT_VERSION_CHECK(5, 8, 0)
-    m_WebEngineView->settings()->setAttribute(QWebEngineSettings::FocusOnNavigationEnabled, false);
-  #endif
+  m_WebEngineView->settings()->setAttribute(QWebEngineSettings::FocusOnNavigationEnabled, false);
 
   connect(m_WebEngineView, SIGNAL(loadFinished(bool)), parent, SLOT(OnLoadFinished(bool)));
 
   auto layout = new QGridLayout(parent);
   layout->setMargin(0);
   layout->addWidget(m_WebEngineView);
 
   parent->setLayout(layout);
 
   m_ChartTypeToName.emplace(ChartType::bar, "bar");
   m_ChartTypeToName.emplace(ChartType::line, "line");
   m_ChartTypeToName.emplace(ChartType::spline, "spline");
   m_ChartTypeToName.emplace(ChartType::pie, "pie");
   m_ChartTypeToName.emplace(ChartType::area, "area");
   m_ChartTypeToName.emplace(ChartType::area_spline, "area-spline");
   m_ChartTypeToName.emplace(ChartType::scatter, "scatter");
 
   m_LegendPositionToName.emplace(LegendPosition::bottom, "bottom");
   m_LegendPositionToName.emplace(LegendPosition::right, "right");
   m_LegendPositionToName.emplace(LegendPosition::inset, "inset");
 
   m_LineStyleToName.emplace(LineStyle::solid, "solid");
   m_LineStyleToName.emplace(LineStyle::dashed, "dashed");
 
   m_AxisScaleToName.emplace(AxisScale::linear, "");
   m_AxisScaleToName.emplace(AxisScale::log, "log");
 }
 
 QmitkChartWidget::Impl::~Impl()
 {
 }
 
 void QmitkChartWidget::Impl::AddData1D(const std::vector<double>& data1D, const std::string& label, QmitkChartWidget::ChartType chartType) {
   std::map<double, double> transformedData2D;
   unsigned int count = 0;
   //transform the 1D data to 2D data
   for (const auto& ele : data1D)
   {
     transformedData2D[count] = ele;
     count++;
   }
 
   AddData2D(transformedData2D, label, chartType);
 }
 
 void QmitkChartWidget::Impl::AddData2D(const std::map<double, double>& data2D, const std::string& label, QmitkChartWidget::ChartType chartType)
 {
   QMap<QVariant, QVariant> data2DConverted;
   for (const auto& aValue : data2D)
   {
     data2DConverted.insert(aValue.first, aValue.second);
   }
   const std::string chartTypeName(m_ChartTypeToName.at(chartType));
 
   auto definedLabels = GetDataLabels(m_C3xyData);
   auto uniqueLabel = GetUniqueLabelName(definedLabels, label);
   if (chartType == ChartType::scatter)
   {
     SetShowDataPoints(true);
     MITK_INFO << "Enabling data points for all because of scatter plot";
   }
 
   m_C3xyData.push_back(std::make_unique<QmitkChartxyData>(data2DConverted, QVariant(QString::fromStdString(uniqueLabel)), QVariant(QString::fromStdString(chartTypeName))));
 }
 
 void QmitkChartWidget::Impl::RemoveData(const std::string& label)
 {
   for (ChartxyDataVector::iterator iter = m_C3xyData.begin(); iter != m_C3xyData.end(); ++iter)
   {
     if ((*iter)->GetLabel().toString().toStdString() == label)
     {
       m_C3xyData.erase(iter);
       return;
     }
   }
 
   throw std::invalid_argument("Cannot Remove Data because the label does not exist.");
 }
 
 void QmitkChartWidget::Impl::ClearData()
 {
   for (auto& xyData : m_C3xyData)
   {
     m_WebChannel->deregisterObject(xyData.get());
   }
   m_C3xyData.clear();
 }
 
 std::string CheckForCorrectHex(const std::string& colorName)
 {
   std::regex rgx("([A-Fa-f0-9]{6}|[A-Fa-f0-9]{3})");
   std::smatch match;
 
   if (!colorName.empty() && colorName.at(0)!='#' && std::regex_search(colorName.begin(), colorName.end(), match, rgx))
   {
     return "#" + colorName;
   }
   else {
     return colorName;
   }
 }
 
 void QmitkChartWidget::Impl::SetColor(const std::string& label, const std::string& colorName)
 {
   auto element = GetDataElementByLabel(label);
   if (element)
   {
     auto colorChecked = CheckForCorrectHex(colorName);
     element->SetColor(QVariant(QString::fromStdString(colorName)));
   }
 }
 
 void QmitkChartWidget::Impl::SetLineStyle(const std::string& label, LineStyle style)
 {
   auto element = GetDataElementByLabel(label);
   //only has effect with chart type line
   if (element && element->GetChartType() == QVariant(QString::fromStdString(ConvertChartTypeToString(ChartType::line))))
   {
     const std::string lineStyleName(m_LineStyleToName.at(style));
     element->SetLineStyle(QVariant(QString::fromStdString(lineStyleName)));
   }
 }
 
 void QmitkChartWidget::Impl::SetYAxisScale(AxisScale scale)
 {
   const std::string axisScaleName(m_AxisScaleToName.at(scale));
   m_C3Data.SetYAxisScale(QString::fromStdString(axisScaleName));
 }
 
 QmitkChartxyData* QmitkChartWidget::Impl::GetDataElementByLabel(const std::string& label) const
 {
   for (const auto& qmitkChartxyData : m_C3xyData)
   {
     if (qmitkChartxyData->GetLabel().toString() == label.c_str())
     {
       return qmitkChartxyData.get();
     }
   }
 
   MITK_WARN << "label " << label << " not found in QmitkChartWidget";
   return nullptr;
 }
 
 QList<QVariant> QmitkChartWidget::Impl::GetDataLabels(const ChartxyDataVector& c3xyData) const
 {
   QList<QVariant> dataLabels;
   for (auto element = c3xyData.begin(); element != c3xyData.end(); ++element)
   {
     dataLabels.push_back((*element)->GetLabel());
   }
   return dataLabels;
 }
 
 void QmitkChartWidget::Impl::SetXAxisLabel(const std::string& label)
 {
   m_C3Data.SetXAxisLabel(QString::fromStdString(label));
 }
 
 void QmitkChartWidget::Impl::SetYAxisLabel(const std::string& label)
 {
   m_C3Data.SetYAxisLabel(QString::fromStdString(label));
 }
 
 void QmitkChartWidget::Impl::SetTitle(const std::string& title)
 {
   m_C3Data.SetTitle(QString::fromStdString(title));
 }
 
 void QmitkChartWidget::Impl::SetLegendPosition(QmitkChartWidget::LegendPosition legendPosition)
 {
   const std::string legendPositionName(m_LegendPositionToName.at(legendPosition));
   m_C3Data.SetLegendPosition(QString::fromStdString(legendPositionName));
 }
 
 void QmitkChartWidget::Impl::SetShowLegend(bool show)
 {
   m_C3Data.SetShowLegend(show);
 }
 
 void QmitkChartWidget::Impl::SetShowDataPoints(bool showDataPoints)
 {
   if (showDataPoints == true) {
     m_C3Data.SetDataPointSize(3);
   }
   else {
     m_C3Data.SetDataPointSize(0);
   }
 }
 
 void QmitkChartWidget::Impl::Show(bool showSubChart)
 {
   if (m_C3xyData.empty())
   {
     mitkThrow() << "no data available for display in chart";
   }
 
   m_C3Data.SetAppearance(showSubChart, m_C3xyData.front()->GetChartType() == QVariant("pie"));
   InitializeJavaScriptChart();
 }
 
 void QmitkChartWidget::Impl::SetChartType(QmitkChartWidget::ChartType chartType)
 {
   for (auto iterator = m_C3xyData.begin(); iterator != m_C3xyData.end(); ++iterator)
   {
     SetChartTypeByLabel((*iterator)->GetLabel().toString().toStdString(), chartType);
   }
 
   auto chartTypeName = ConvertChartTypeToString(chartType);
   const QString command = QString::fromStdString("transformView('" + chartTypeName + "')");
   CallJavaScriptFuntion(command);
 }
 
 void QmitkChartWidget::Impl::SetChartTypeByLabel(const std::string& label, QmitkChartWidget::ChartType chartType)
 {
   auto element = GetDataElementByLabel(label);
   if (element)
   {
     if (chartType == ChartType::scatter)
     {
       SetShowDataPoints(true);
       MITK_INFO << "Enabling data points for all because of scatter plot";
     }
     auto chartTypeName = ConvertChartTypeToString(chartType);
     element->SetChartType(QVariant(QString::fromStdString(chartTypeName)));
   }
 }
 
 std::string QmitkChartWidget::Impl::ConvertChartTypeToString(QmitkChartWidget::ChartType chartType) const
 {
   return m_ChartTypeToName.at(chartType);
 }
 
 void QmitkChartWidget::Impl::CallJavaScriptFuntion(const QString& command)
 {
   m_WebEngineView->page()->runJavaScript(command);
 }
 
 void QmitkChartWidget::Impl::ClearJavaScriptChart()
 {
   m_WebEngineView->setUrl(QUrl(QStringLiteral("qrc:///C3js/empty.html")));
 }
 
 void QmitkChartWidget::Impl::InitializeJavaScriptChart()
 {
   m_WebChannel->registerObject(QStringLiteral("chartData"), &m_C3Data);
   unsigned count = 0;
   for (auto& xyData : m_C3xyData)
   {
     QString variableName = "xyData" + QString::number(count);
     m_WebChannel->registerObject(variableName, xyData.get());
 	  count++;
   }
   m_WebEngineView->load(QUrl(QStringLiteral("qrc:///C3js/QmitkChartWidget.html")));
 }
 
 std::string QmitkChartWidget::Impl::GetUniqueLabelName(const QList<QVariant>& labelList, const std::string& label) const
 {
   QString currentLabel = QString::fromStdString(label);
   int counter = 0;
   while (labelList.contains(currentLabel))
   {
     currentLabel = QString::fromStdString(label + std::to_string(counter));
     counter++;
   }
   return currentLabel.toStdString();
 }
 
 QmitkChartWidget::QmitkChartWidget(QWidget* parent)
   : QWidget(parent)
   , m_Impl(new Impl(this))
 {
 }
 
 QmitkChartWidget::~QmitkChartWidget()
 {
 }
 
 void QmitkChartWidget::AddData2D(const std::map<double, double>& data2D, const std::string& label, ChartType type)
 {
   m_Impl->AddData2D(data2D, label, type);
 }
 
 void QmitkChartWidget::SetColor(const std::string& label, const std::string& colorName)
 {
   m_Impl->SetColor(label, colorName);
 }
 
 void QmitkChartWidget::SetLineStyle(const std::string& label, LineStyle style)
 {
   m_Impl->SetLineStyle(label, style);
 }
 
 void QmitkChartWidget::SetYAxisScale(AxisScale scale)
 {
   m_Impl->SetYAxisScale(scale);
 }
 
 void QmitkChartWidget::AddData1D(const std::vector<double>& data1D, const std::string& label, ChartType type)
 {
   m_Impl->AddData1D(data1D, label, type);
 }
 
 void QmitkChartWidget::RemoveData(const std::string& label)
 {
   m_Impl->RemoveData(label);
 }
 
 void QmitkChartWidget::SetXAxisLabel(const std::string & label)
 {
 	m_Impl->SetXAxisLabel(label);
 }
 
 void QmitkChartWidget::SetYAxisLabel(const std::string & label)
 {
 	m_Impl->SetYAxisLabel(label);
 }
 
 void QmitkChartWidget::SetTitle(const std::string & title)
 {
   m_Impl->SetTitle(title);
 }
 
 void QmitkChartWidget::SetShowDataPoints(bool showDataPoints)
 {
   m_Impl->SetShowDataPoints(showDataPoints);
 }
 
 void QmitkChartWidget::SetChartTypeForAllDataAndReload(ChartType type)
 {
   m_Impl->SetChartType(type);
 }
 
 void QmitkChartWidget::SetChartType(const std::string& label, ChartType type)
 {
   m_Impl->SetChartTypeByLabel(label, type);
 }
 
 void QmitkChartWidget::SetLegendPosition(LegendPosition position)
 {
   m_Impl->SetLegendPosition(position);
 }
 
 void QmitkChartWidget::SetShowLegend(bool show)
 {
   m_Impl->SetShowLegend(show);
 }
 
 void QmitkChartWidget::Show(bool showSubChart)
 {
   m_Impl->Show(showSubChart);
 }
 
 void QmitkChartWidget::Clear()
 {
   m_Impl->ClearData();
 	m_Impl->ClearJavaScriptChart();
 }
 
 void QmitkChartWidget::OnLoadFinished(bool isLoadSuccessful)
 {
   if(isLoadSuccessful)
   {
     emit PageSuccessfullyLoaded();
   }
 }
 
 void QmitkChartWidget::SetTheme(ChartStyle themeEnabled)
 {
   QString command;
   if (themeEnabled == ChartStyle::darkstyle)
   {
     command = QString("changeTheme('dark')");
   }
   else {
     command = QString("changeTheme('light')");
   }
   m_Impl->CallJavaScriptFuntion(command);
 }
 
 void QmitkChartWidget::Reload(bool showSubChart)
 {
   QString subChartString;
   if (showSubChart)
   {
     subChartString = "true";
   }
   else
   {
     subChartString = "false";
   }
   const QString command = QString("ReloadChart(" + subChartString + ")");
   m_Impl->CallJavaScriptFuntion(command);
 }
diff --git a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
index 5942405f0d..bcf8c0a50f 100644
--- a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
+++ b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
@@ -1,1287 +1,1266 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include "QmitkImageStatisticsView.h"
 
 // Qt includes
 #include <QClipboard>
 #include <QScrollBar>
 #include <QVector>
 
 // berry includes
 #include <berryIWorkbenchPage.h>
 
 // mitk includes
 #include <mitkNodePredicateDataType.h>
 #include <mitkNodePredicateOr.h>
 #include <mitkPlanarFigureInteractor.h>
 #include <mitkImageTimeSelector.h>
 #include <QmitkRenderWindow.h>
 #include <QmitkChartWidget.h>
 #include <mitkImageCast.h>
 #include <mitkImageStatisticsHolder.h>
 
 // itk includes
 #include "itksys/SystemTools.hxx"
 #include "itkImageRegionConstIteratorWithIndex.h"
 
 #include <limits>
 
 //blueberry includes
 #include <berryWorkbenchPlugin.h>
 #include <berryQtPreferences.h>
 
 const std::string QmitkImageStatisticsView::VIEW_ID = "org.mitk.views.imagestatistics";
 const int QmitkImageStatisticsView::STAT_TABLE_BASE_HEIGHT = 180;
 
 QmitkImageStatisticsView::QmitkImageStatisticsView(QObject* /*parent*/, const char* /*name*/)
 : m_Controls( nullptr ),
   m_SelectedImage( nullptr ),
   m_SelectedImageMask( nullptr ),
   m_SelectedPlanarFigure( nullptr ),
   m_ImageObserverTag( -1 ),
   m_ImageMaskObserverTag( -1 ),
   m_PlanarFigureObserverTag( -1 ),
   m_TimeObserverTag( -1 ),
   m_CurrentStatisticsValid( false ),
   m_StatisticsUpdatePending( false ),
   m_DataNodeSelectionChanged ( false ),
   m_Visible(false)
 {
   this->m_CalculationThread = new QmitkImageStatisticsCalculationThread;
 }
 
 QmitkImageStatisticsView::~QmitkImageStatisticsView()
 {
   if ( m_SelectedImage != nullptr )
     m_SelectedImage->RemoveObserver( m_ImageObserverTag );
   if ( m_SelectedImageMask != nullptr )
     m_SelectedImageMask->RemoveObserver( m_ImageMaskObserverTag );
   if ( m_SelectedPlanarFigure != nullptr )
     m_SelectedPlanarFigure->RemoveObserver( m_PlanarFigureObserverTag );
 
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
   delete this->m_CalculationThread;
 }
 
 
 void QmitkImageStatisticsView::CreateQtPartControl(QWidget *parent)
 {
   if (m_Controls == nullptr)
   {
     m_Controls = new Ui::QmitkImageStatisticsViewControls;
     m_Controls->setupUi(parent);
     CreateConnections();
 
     m_Controls->m_ErrorMessageLabel->hide();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_Controls->m_BinSizeFrame->setEnabled(false);
-    #if QT_VERSION < QT_VERSION_CHECK(5, 10, 0)
-      m_Controls->m_StatisticsWidgetStack->setVisible(false);
-      m_Controls->label_HistogramIsInvisibleWarning->setEnabled(true);
-      m_Controls->label_HistogramIsInvisibleWarning->setVisible(true);
-      m_Controls->label_HistogramIsInvisibleWarning->setText("<font color='red'>Histogram is not visible because Qt 5.10 is required. You can use the button <i>Copy to Clipboard</i> below to retrieve values.</font>");
-      m_Controls->groupBox_plot->setVisible(false);
-    #else
-      m_Controls->label_HistogramIsInvisibleWarning->setVisible(false);
-    #endif
-
   }
 }
 
 void QmitkImageStatisticsView::OnPageSuccessfullyLoaded()
 {
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   QString styleName = m_StylePref->Get(berry::QtPreferences::QT_STYLE_NAME, "");
 
   if (styleName == ":/org.blueberry.ui.qt/darkstyle.qss")
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::darkstyle);
   }
   else
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::lightstyle);
   }
 }
 
 void QmitkImageStatisticsView::CreateConnections()
 {
   if ( m_Controls )
   {
     connect( (QObject*)(this->m_Controls->m_ButtonCopyHistogramToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardHistogramButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_ButtonCopyStatisticsToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardStatisticsButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_IgnoreZerosCheckbox), SIGNAL(clicked()),(QObject*) this, SLOT(OnIgnoreZerosCheckboxClicked()) );
     connect( (QObject*) this->m_CalculationThread, SIGNAL(finished()),this, SLOT( OnThreadedStatisticsCalculationEnds()),Qt::QueuedConnection);
     connect( (QObject*) this, SIGNAL(StatisticsUpdate()),this, SLOT( RequestStatisticsUpdate()), Qt::QueuedConnection);
     connect( (QObject*) this->m_Controls->m_StatisticsTable, SIGNAL(cellDoubleClicked(int,int)),this, SLOT( JumpToCoordinates(int,int)) );
     connect((QObject*)(this->m_Controls->m_barRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnBarRadioButtonSelected()));
     connect((QObject*)(this->m_Controls->m_lineRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnLineRadioButtonSelected()));
     connect( (QObject*) (this->m_Controls->m_HistogramNBinsSpinbox), SIGNAL(editingFinished()), this, SLOT(OnHistogramNBinsCheckBoxValueChanged()));
     connect((QObject*)(this->m_Controls->m_UseDefaultNBinsCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnDefaultNBinsSpinBoxChanged()));
     connect((QObject*)(this->m_Controls->m_ShowSubchartCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnShowSubchartBoxChanged()));
     connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   }
 }
 
 void QmitkImageStatisticsView::OnDefaultNBinsSpinBoxChanged()
 {
   if (this->m_Controls->m_UseDefaultNBinsCheckBox->isChecked()) {
     m_Controls->m_HistogramNBinsSpinbox->setValue(100);
     this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
     m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   }
   m_Controls->m_BinSizeFrame->setEnabled(!m_Controls->m_UseDefaultNBinsCheckBox->isChecked());
 
   this->UpdateStatistics();
 
 }
 
 void QmitkImageStatisticsView::OnShowSubchartBoxChanged()
 {
   bool showSubchart = this->m_Controls->m_ShowSubchartCheckBox->isChecked();
   this->m_Controls->m_JSHistogram->Reload(showSubchart);
 }
 
 
 void QmitkImageStatisticsView::OnBarRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::bar);
 }
 
 void QmitkImageStatisticsView::OnLineRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::line);
 }
 
 void QmitkImageStatisticsView::PartClosed(const berry::IWorkbenchPartReference::Pointer& )
 {
 }
 
 void QmitkImageStatisticsView::OnTimeChanged(const itk::EventObject& e)
 {
   if (this->m_SelectedDataNodes.isEmpty() || this->m_SelectedImage == nullptr)
     return;
 
   const mitk::SliceNavigationController::GeometryTimeEvent* timeEvent =
       dynamic_cast<const mitk::SliceNavigationController::GeometryTimeEvent*>(&e);
   assert(timeEvent != nullptr);
   int timestep = timeEvent->GetPos();
 
   if (this->m_SelectedImage->GetTimeSteps() > 1)
   {
     for (int x = 0; x < this->m_Controls->m_StatisticsTable->columnCount(); x++)
     {
       for (int y = 0; y < this->m_Controls->m_StatisticsTable->rowCount(); y++)
       {
         QTableWidgetItem* item = this->m_Controls->m_StatisticsTable->item(y, x);
         if (item == nullptr)
           break;
 
         if (x == timestep)
         {
           item->setBackgroundColor(Qt::yellow);
         }
         else
         {
           if (y % 2 == 0)
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().base());
           else
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().alternateBase());
         }
       }
     }
 
     this->m_Controls->m_StatisticsTable->viewport()->update();
   }
 
   if ((this->m_SelectedImage->GetTimeSteps() == 1 && timestep == 0) ||
       this->m_SelectedImage->GetTimeSteps() > 1)
   {
-    // display histogram for selected timestep
-    //bug in Qt thats leads to crash in debug builds. Fixed in Qt 5.10
-    #if QT_VERSION >= QT_VERSION_CHECK(5, 10, 0)
-      m_Controls->m_JSHistogram->Clear();
-    #endif
+    m_Controls->m_JSHistogram->Clear();
     QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer histogram =
         (QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer)this->m_CalculationThread->GetTimeStepHistogram(timestep);
 
     if (histogram.IsNotNull())
     {
       bool statisticsUpdateSuccessful = this->m_CalculationThread->GetStatisticsUpdateSuccessFlag();
 
       if (statisticsUpdateSuccessful)
       {
 
         auto imageNameLabel = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         this->m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageNameLabel);
         if (this->m_Controls->m_lineRadioButton->isChecked())
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::line);
         }
         else
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::bar);
         }
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Grey value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         this->m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
       }
     }
   }
 }
 
 void QmitkImageStatisticsView::JumpToCoordinates(int row ,int col)
 {
   if(m_SelectedDataNodes.isEmpty())
   {
     MITK_WARN("QmitkImageStatisticsView") << "No data node selected for statistics calculation." ;
     return;
   }
 
   mitk::Point3D world;
   if (row==5 && !m_WorldMinList.empty())
     world = m_WorldMinList[col];
   else if (row==4 && !m_WorldMaxList.empty())
     world = m_WorldMaxList[col];
   else
     return;
 
   mitk::IRenderWindowPart* part = this->GetRenderWindowPart();
   if (part)
   {
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("sagittal")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("coronal")->GetSliceNavigationController()->SelectSliceByPoint(world);
 
     mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(), col);
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SetGeometryTime(timeEvent);
   }
 }
 
 void QmitkImageStatisticsView::OnIgnoreZerosCheckboxClicked()
 {
   emit StatisticsUpdate();
 }
 
 void QmitkImageStatisticsView::OnClipboardHistogramButtonClicked()
 {
   if (!m_CurrentStatisticsValid)
   {
     QApplication::clipboard()->clear();
   }
 
   if (m_SelectedPlanarFigure == nullptr)
   {
     const unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
     typedef mitk::ImageStatisticsCalculator::HistogramType HistogramType;
     const HistogramType *histogram = this->m_CalculationThread->GetTimeStepHistogram(t).GetPointer();
 
     QString clipboard("Measurement \t Frequency\n");
     for (HistogramType::ConstIterator it = histogram->Begin();
       it != histogram->End();
       ++it)
     {
       clipboard = clipboard.append("%L1 \t %L2\n")
         .arg(it.GetMeasurementVector()[0], 0, 'f', 2)
         .arg(it.GetFrequency());
     }
 
     QApplication::clipboard()->setText(
       clipboard, QClipboard::Clipboard);
   }
   //If a (non-closed) PlanarFigure is selected, display a line profile widget
   else if (m_SelectedPlanarFigure != nullptr)
   {
     QString clipboard("Pixel \t Intensity\n");
     for (unsigned int i = 0; i < m_IntensityProfileList.size(); i++)
     {
       clipboard =
         clipboard.append("%L1 \t %L2\n").arg(QString::number(i)).arg(QString::number(m_IntensityProfileList.at(i)));
     }
     QApplication::clipboard()->setText(clipboard, QClipboard::Clipboard);
   }
 }
 
 void QmitkImageStatisticsView::OnClipboardStatisticsButtonClicked()
 {
   QLocale tempLocal;
   QLocale::setDefault(QLocale(QLocale::English, QLocale::UnitedStates));
   if ( m_CurrentStatisticsValid && !( m_SelectedPlanarFigure != nullptr))
    {
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics =
       this->m_CalculationThread->GetStatisticsData();
 
     // Set time borders for for loop ;)
     unsigned int startT, endT;
     if(this->m_Controls->m_CheckBox4dCompleteTable->checkState()==Qt::CheckState::Unchecked)
     {
         startT = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
           GetPos();
         endT = startT+1;
     }
     else
     {
         startT = 0;
         endT = statistics.size();
     }
     QVector< QVector<QString> > statisticsTable;
     QStringList headline{ "Timestep", "Mean", "Median", "StdDev", "RMS", "Max", "Min", "NumberOfVoxels", "Skewness", "Kurtosis", "Uniformity", "Entropy", "MPP", "UPP", "V [mm³]" };
 
     for(int i=0;i<headline.size();i++)
     {
         QVector<QString> row;
         row.append(headline.at(i));
         statisticsTable.append(row);
     }
 
     // Fill Table
     for(unsigned int t=startT;t<endT;t++)
     {
         // Copy statistics to clipboard ("%Ln" will use the default locale for
         // number formatting)
         QStringList value;
         value << QString::number(t)
               << QString::number(statistics[t]->GetMean())
               << QString::number(statistics[t]->GetMedian())
               << QString::number(statistics[t]->GetStd())
               << QString::number(statistics[t]->GetRMS())
               << QString::number(statistics[t]->GetMax())
               << QString::number(statistics[t]->GetMin())
               << QString::number(statistics[t]->GetN())
               << QString::number(statistics[t]->GetSkewness())
               << QString::number(statistics[t]->GetKurtosis())
               << QString::number(statistics[t]->GetUniformity())
               << QString::number(statistics[t]->GetEntropy())
               << QString::number(statistics[t]->GetMPP())
               << QString::number(statistics[t]->GetUPP())
               << QString::number(m_Controls->m_StatisticsTable->item(7, 0)->data(Qt::DisplayRole).toDouble());
 
          for(int z=0;z<value.size();z++)
          {
              statisticsTable[z].append(value.at(z));
          }
     }
 
     // Create output string
     QString clipboard;
     for(int i=0;i<statisticsTable.size();i++)
     {
         for(int t=0;t<statisticsTable.at(i).size();t++)
         {
             clipboard.append(statisticsTable.at(i).at(t));
             clipboard.append("\t");
         }
         clipboard.append("\n");
     }
     QApplication::clipboard()->setText(clipboard, QClipboard::Clipboard);
   }
   else
   {
     QApplication::clipboard()->clear();
   }
   QLocale::setDefault(tempLocal);
 }
 
 void QmitkImageStatisticsView::OnSelectionChanged( berry::IWorkbenchPart::Pointer /*part*/,
     const QList<mitk::DataNode::Pointer> &nodes )
 {
   if (this->m_Visible)
   {
     this->SelectionChanged( nodes );
   }
   else
   {
     this->m_DataNodeSelectionChanged = true;
   }
 }
 
 void QmitkImageStatisticsView::SelectionChanged(const QList<mitk::DataNode::Pointer> &selectedNodes)
 {
-  //Clear Histogram if data node is deselected
-  //bug in Qt thats leads to crash in debug builds. Fixed in Qt 5.10
-  #if QT_VERSION >= QT_VERSION_CHECK(5, 10, 0)
   m_Controls->m_JSHistogram->Clear();
-  #endif
 
   if( this->m_StatisticsUpdatePending )
   {
     this->m_DataNodeSelectionChanged = true;
     return; // not ready for new data now!
   }
 
   if (selectedNodes.size() == this->m_SelectedDataNodes.size())
   {
     int i = 0;
     for (; i < selectedNodes.size(); ++i)
     {
       if (selectedNodes.at(i) != this->m_SelectedDataNodes.at(i))
       {
         break;
       }
     }
     // node selection did not change
     if (i == selectedNodes.size()) return;
   }
 
   //reset the feature image and image mask field
   m_Controls->m_SelectedFeatureImageLabel->setText("None");
   m_Controls->m_SelectedMaskLabel->setText("None");
 
   this->ReinitData();
   if (selectedNodes.isEmpty())
   {
     DisableHistogramGUIElements();
   }
   else
   {
     EnableHistogramGUIElements();
     ResetHistogramGUIElementsToDefault();
   }
   if(selectedNodes.size() == 1 || selectedNodes.size() == 2)
   {
     bool isBinary = false;
     selectedNodes.value(0)->GetBoolProperty("binary",isBinary);
     mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
     isBinary |= isLabelSet->CheckNode(selectedNodes.value(0));
     if(isBinary)
     {
       EnableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
     }
     for (int i= 0; i< selectedNodes.size(); ++i)
     {
       this->m_SelectedDataNodes.push_back(selectedNodes.at(i));
     }
     this->m_DataNodeSelectionChanged = false;
     this->m_Controls->m_ErrorMessageLabel->setText( "" );
     this->m_Controls->m_ErrorMessageLabel->hide();
     emit StatisticsUpdate();
   }
   else
   {
     this->m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::DisableHistogramGUIElements()
 {
   m_Controls->m_InfoLabel->setText("");
   m_Controls->groupBox_histogram->setEnabled(false);
   m_Controls->groupBox_statistics->setEnabled(false);
 }
 
 void QmitkImageStatisticsView::ResetHistogramGUIElementsToDefault()
 {
   m_Controls->m_barRadioButton->setChecked(true);
   m_Controls->m_HistogramNBinsSpinbox->setValue(100);
   m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   m_Controls->m_UseDefaultNBinsCheckBox->setChecked(true);
   m_Controls->m_ShowSubchartCheckBox->setChecked(true);
   m_Controls->m_BinSizeFrame->setEnabled(false);
   m_Controls->m_barRadioButton->setEnabled(true);
   m_Controls->m_lineRadioButton->setEnabled(true);
   m_Controls->m_HistogramNBinsSpinbox->setEnabled(true);
   this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
 }
 
 void QmitkImageStatisticsView::EnableHistogramGUIElements()
 {
   m_Controls->groupBox_histogram->setEnabled(true);
   m_Controls->groupBox_plot->setEnabled(true);
   m_Controls->groupBox_statistics->setEnabled(true);
 }
 
 void QmitkImageStatisticsView::ReinitData()
 {
   while( this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if(this->m_SelectedImage != nullptr)
   {
     this->m_SelectedImage->RemoveObserver( this->m_ImageObserverTag);
     this->m_SelectedImage = nullptr;
   }
   if(this->m_SelectedImageMask != nullptr)
   {
     this->m_SelectedImageMask->RemoveObserver( this->m_ImageMaskObserverTag);
     this->m_SelectedImageMask = nullptr;
   }
   if(this->m_SelectedPlanarFigure != nullptr)
   {
     this->m_SelectedPlanarFigure->RemoveObserver( this->m_PlanarFigureObserverTag);
     this->m_SelectedPlanarFigure = nullptr;
   }
   this->m_SelectedDataNodes.clear();
   this->m_StatisticsUpdatePending = false;
 
   m_Controls->m_ErrorMessageLabel->setText( "" );
   m_Controls->m_ErrorMessageLabel->hide();
   this->InvalidateStatisticsTableView();
   m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
 }
 
 void QmitkImageStatisticsView::OnThreadedStatisticsCalculationEnds()
 {
   m_Controls->m_ErrorMessageLabel->setText("");
   m_Controls->m_ErrorMessageLabel->hide();
   this->WriteStatisticsToGUI();
 }
 
 void QmitkImageStatisticsView::UpdateStatistics()
 {
   mitk::IRenderWindowPart* renderPart = this->GetRenderWindowPart();
   if ( renderPart == nullptr )
   {
     this->m_StatisticsUpdatePending =  false;
     return;
   }
   m_WorldMinList.clear();
   m_WorldMaxList.clear();
 
   // classify selected nodes
   mitk::NodePredicateDataType::Pointer isImage = mitk::NodePredicateDataType::New("Image");
   mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
   mitk::NodePredicateOr::Pointer imagePredicate = mitk::NodePredicateOr::New(isImage, isLabelSet);
 
   std::string maskName;
   std::string maskType;
   std::string featureImageName;
   unsigned int maskDimension = 0;
 
   // reset data from last run
   ITKCommandType::Pointer changeListener = ITKCommandType::New();
   changeListener->SetCallbackFunction( this, &QmitkImageStatisticsView::SelectedDataModified );
 
   mitk::DataNode::Pointer planarFigureNode;
   for( int i= 0 ; i < this->m_SelectedDataNodes.size(); ++i)
   {
     mitk::PlanarFigure::Pointer planarFig = dynamic_cast<mitk::PlanarFigure*>(this->m_SelectedDataNodes.at(i)->GetData());
     if( imagePredicate->CheckNode(this->m_SelectedDataNodes.at(i)) )
     {
       bool isMask = false;
       this->m_SelectedDataNodes.at(i)->GetPropertyValue("binary", isMask);
       isMask |= isLabelSet->CheckNode(this->m_SelectedDataNodes.at(i));
 
       if( this->m_SelectedImageMask == nullptr && isMask)
       {
         this->m_SelectedImageMask = dynamic_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
         this->m_ImageMaskObserverTag = this->m_SelectedImageMask->AddObserver(itk::ModifiedEvent(), changeListener);
 
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = m_SelectedImageMask->GetNameOfClass();
         maskDimension = 3;
       }
       else if( !isMask )
       {
         if(this->m_SelectedImage == nullptr)
         {
           this->m_SelectedImage = static_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
           this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
         }
         featureImageName = this->m_SelectedDataNodes.at(i)->GetName();
       }
     }
     else if (planarFig.IsNotNull())
     {
       if(this->m_SelectedPlanarFigure == nullptr)
       {
         this->m_SelectedPlanarFigure = planarFig;
         this->m_PlanarFigureObserverTag  =
             this->m_SelectedPlanarFigure->AddObserver(mitk::EndInteractionPlanarFigureEvent(), changeListener);
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = this->m_SelectedPlanarFigure->GetNameOfClass();
         maskDimension = 2;
         planarFigureNode = m_SelectedDataNodes.at(i);
       }
     }
     else
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Invalid data node type!</font>");
       m_Controls->m_ErrorMessageLabel->show();
     }
   }
 
   if(maskName == "")
   {
     maskName = "None";
     maskType = "";
     maskDimension = 0;
   }
 
   if(featureImageName == "")
   {
     featureImageName = "None";
   }
 
   if (m_SelectedPlanarFigure != nullptr && m_SelectedImage == nullptr)
   {
     mitk::DataStorage::SetOfObjects::ConstPointer parentSet = this->GetDataStorage()->GetSources(planarFigureNode);
     for (unsigned int i=0; i<parentSet->Size(); i++)
     {
       mitk::DataNode::Pointer node = parentSet->ElementAt(i);
       if( imagePredicate->CheckNode(node) )
       {
         bool isMask = false;
         node->GetPropertyValue("binary", isMask);
         isMask |= isLabelSet->CheckNode(node);
 
         if( !isMask )
         {
           if(this->m_SelectedImage == nullptr)
           {
             this->m_SelectedImage = static_cast<mitk::Image*>(node->GetData());
             this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
           }
         }
       }
     }
   }
 
   unsigned int timeStep = renderPart->GetTimeNavigationController()->GetTime()->GetPos();
 
   if ( m_SelectedImage != nullptr && m_SelectedImage->IsInitialized())
   {
     // Check if a the selected image is a multi-channel image. If yes, statistics
     // cannot be calculated currently.
     if ( m_SelectedImage->GetPixelType().GetNumberOfComponents() > 1 )
     {
       m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Multi-component images not supported.</font>" );
       m_Controls->m_ErrorMessageLabel->show();
 
       this->InvalidateStatisticsTableView();
       m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
       m_CurrentStatisticsValid = false;
       this->m_StatisticsUpdatePending = false;
       this->DisableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
       return;
     }
 
     std::stringstream maskLabel;
     maskLabel << maskName;
     if ( maskDimension > 0 )
     {
       maskLabel << "  [" << maskDimension << "D " << maskType << "]";
     }
     m_Controls->m_SelectedMaskLabel->setText( maskLabel.str().c_str() );
     m_Controls->m_SelectedFeatureImageLabel->setText(featureImageName.c_str());
 
     // check time step validity
     if(m_SelectedImage->GetDimension() <= 3 && timeStep > m_SelectedImage->GetDimension(3)-1)
     {
       timeStep = m_SelectedImage->GetDimension(3)-1;
     }
 
     // Add the used mask time step to the mask label so the user knows which mask time step was used
     // if the image time step is bigger than the total number of mask time steps (see
     // ImageStatisticsCalculator::ExtractImageAndMask)
     if (m_SelectedImageMask != nullptr)
     {
       unsigned int maskTimeStep = timeStep;
 
       if (maskTimeStep >= m_SelectedImageMask->GetTimeSteps())
       {
         maskTimeStep = m_SelectedImageMask->GetTimeSteps() - 1;
       }
 
       m_Controls->m_SelectedMaskLabel->setText(m_Controls->m_SelectedMaskLabel->text() +
           QString(" (t=") +
           QString::number(maskTimeStep) +
           QString(")"));
     }
 
     // check if the segmentation mask is empty
     if (m_SelectedImageMask != nullptr)
     {
       auto maskStatistics = m_SelectedImageMask->GetStatistics();
       mitk::ScalarType maskMaxValue = maskStatistics->GetScalarValueMax(0);
       if (m_SelectedImageMask->GetDimension() == 4) {
         for (unsigned int curTimestep = 1; curTimestep < m_SelectedImageMask->GetTimeSteps(); curTimestep++) {
           maskMaxValue = std::max(maskStatistics->GetScalarValueMax(curTimestep), maskMaxValue);
         }
       }
 
       bool segmentationIsEmpty = maskMaxValue == 0;
 
       if (segmentationIsEmpty)
       {
         m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Empty segmentation mask selected...</font>" );
         m_Controls->m_ErrorMessageLabel->show();
         this->m_StatisticsUpdatePending = false;
         return;
       }
     }
 
     //// initialize thread and trigger it
     this->m_CalculationThread->SetIgnoreZeroValueVoxel( m_Controls->m_IgnoreZerosCheckbox->isChecked() );
     this->m_CalculationThread->Initialize( m_SelectedImage, m_SelectedImageMask, m_SelectedPlanarFigure );
     this->m_CalculationThread->SetTimeStep( timeStep );
 
     m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Calculating statistics...</font>");
     m_Controls->m_ErrorMessageLabel->show();
 
     try
     {
       // Compute statistics
       this->m_CalculationThread->start();
     }
     catch ( const mitk::Exception& e)
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.GetDescription()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::runtime_error &e )
     {
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::exception &e )
     {
       MITK_ERROR << "Caught exception: " << e.what();
 
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
   }
   else
   {
     this->m_StatisticsUpdatePending = false;
   }
 }
 
 void QmitkImageStatisticsView::SelectedDataModified()
 {
   if( !m_StatisticsUpdatePending )
   {
     emit StatisticsUpdate();
   }
 }
 
 void QmitkImageStatisticsView::NodeRemoved(const mitk::DataNode *node)
 {
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if (node->GetData() == m_SelectedImage)
   {
     m_SelectedImage = nullptr;
   }
 }
 
 void QmitkImageStatisticsView::RequestStatisticsUpdate()
 {
   if ( !m_StatisticsUpdatePending )
   {
     if(this->m_DataNodeSelectionChanged)
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->m_StatisticsUpdatePending = true;
       this->UpdateStatistics();
     }
   }
   if (this->GetRenderWindowPart())
     this->GetRenderWindowPart()->RequestUpdate();
 }
 
 void QmitkImageStatisticsView::OnHistogramNBinsCheckBoxValueChanged()
 {
     if (static_cast<unsigned int>(m_Controls->m_HistogramNBinsSpinbox->value()) != m_HistogramNBins)
     {
       m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
         this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
         this->UpdateStatistics();
     }
 }
 
 void QmitkImageStatisticsView::WriteStatisticsToGUI()
 {
-  //bug in Qt thats leads to crash in debug builds. Fixed in Qt 5.10
-  #if QT_VERSION >= QT_VERSION_CHECK(5, 10, 0)
   m_Controls->m_JSHistogram->Clear();
-  #endif
   m_IntensityProfileList.clear();
 
   //Disconnect OnLineRadioButtonSelected() to prevent reloading chart when radiobutton is checked programmatically
   disconnect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), 0, 0);
   connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   m_Controls->m_InfoLabel->setText("");
 
   if (m_DataNodeSelectionChanged)
   {
     this->m_StatisticsUpdatePending = false;
     this->RequestStatisticsUpdate();
     return;    // stop visualization of results and calculate statistics of new selection
   }
 
   if (this->m_CalculationThread->GetStatisticsUpdateSuccessFlag())
   {
     if (this->m_CalculationThread->GetStatisticsChangedFlag())
     {
       // Do not show any error messages
       m_Controls->m_ErrorMessageLabel->hide();
       m_CurrentStatisticsValid = true;
     }
 
     if (m_SelectedImage != nullptr) {
       //all statistics are now computed also on planar figures (lines, paths...)!
     // If a (non-closed) PlanarFigure is selected, display a line profile widget
       if (m_SelectedPlanarFigure != nullptr && !m_SelectedPlanarFigure->IsClosed()) {
 
         // check whether PlanarFigure is initialized
         const mitk::PlaneGeometry *planarFigurePlaneGeometry = m_SelectedPlanarFigure->GetPlaneGeometry();
 
         if (planarFigurePlaneGeometry != nullptr)
         {
           unsigned int timeStep = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
           mitk::Image::Pointer image;
 
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4)
           {
             mitk::ImageTimeSelector::Pointer timeSelector = mitk::ImageTimeSelector::New();
             timeSelector->SetInput(this->m_CalculationThread->GetStatisticsImage());
             timeSelector->SetTimeNr(timeStep);
             timeSelector->Update();
 
             image = timeSelector->GetOutput();
           }
           else
           {
             image = this->m_CalculationThread->GetStatisticsImage();
           }
 
           mitk::IntensityProfile::ConstPointer intensityProfile = (mitk::IntensityProfile::ConstPointer)mitk::ComputeIntensityProfile(image, m_SelectedPlanarFigure);
 
           m_IntensityProfileList = ConvertIntensityProfileToVector(intensityProfile);
           auto lineDataLabel = "Intensity profile " + m_Controls->m_SelectedMaskLabel->text().toStdString();
           m_Controls->m_JSHistogram->SetChartType(lineDataLabel, QmitkChartWidget::ChartType::line);
           m_Controls->m_JSHistogram->AddData1D(m_IntensityProfileList, lineDataLabel);
           m_Controls->m_JSHistogram->SetXAxisLabel("Distance");
           m_Controls->m_JSHistogram->SetYAxisLabel("Intensity");
           m_Controls->m_JSHistogram->Show(m_Controls->m_ShowSubchartCheckBox->isChecked());
 
           m_Controls->m_lineRadioButton->setChecked(true);
           m_Controls->m_lineRadioButton->setEnabled(false);
           m_Controls->m_barRadioButton->setEnabled(false);
           m_Controls->m_HistogramNBinsSpinbox->setEnabled(false);
           m_Controls->m_BinSizeFrame->setEnabled(false);
           m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(false);
 
           //Reconnect OnLineRadioButtonSelected()
           connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnLineRadioButtonSelected()));
           auto statisticsVector = this->m_CalculationThread->GetStatisticsData();
           //only one entry (current timestep)
           this->FillLinearProfileStatisticsTableView(statisticsVector.front().GetPointer(), this->m_CalculationThread->GetStatisticsImage());
 
           QString message("<font color='red'>Only linegraph available for an intensity profile!");
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4) {
             message += "Only current timestep displayed!";
           }
           message += "</font>";
           m_Controls->m_InfoLabel->setText(message);
           m_CurrentStatisticsValid = true;
         }
         else
         {
           // Clear statistics, histogram, and GUI
           this->InvalidateStatisticsTableView();
           m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
           m_CurrentStatisticsValid = false;
           m_Controls->m_ErrorMessageLabel->hide();
           m_Controls->m_SelectedMaskLabel->setText("None");
           this->m_StatisticsUpdatePending = false;
           m_Controls->m_InfoLabel->setText("");
           return;
         }
       }
       else
       {
         m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
 
         auto histogram = this->m_CalculationThread->GetTimeStepHistogram(this->m_CalculationThread->GetTimeStep()).GetPointer();
 
         auto imageLabelName = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageLabelName);
         m_Controls->m_JSHistogram->SetChartType(imageLabelName, QmitkChartWidget::ChartType::bar);
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Gray value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(true);
         m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
         this->FillStatisticsTableView(this->m_CalculationThread->GetStatisticsData(), this->m_CalculationThread->GetStatisticsImage());
       }
       m_CurrentStatisticsValid = true;
     }
   }
   else
   {
     m_Controls->m_SelectedMaskLabel->setText("None");
     m_Controls->m_ErrorMessageLabel->setText(m_CalculationThread->GetLastErrorMessage().c_str());
     m_Controls->m_ErrorMessageLabel->show();
 
     // Clear statistics and histogram
     this->InvalidateStatisticsTableView();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_CurrentStatisticsValid = false;
 
   }
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   this->m_StatisticsUpdatePending = false;
 }
 
 void QmitkImageStatisticsView::FillStatisticsTableView(
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics,
     const mitk::Image *image )
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(image->GetTimeSteps());
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(image->GetTimeSteps() > 1);
 
   // Set Checkbox for complete copy of statistic table
   if(image->GetTimeSteps()>1)
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(true);
   }
   else
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(false);
     this->m_Controls->m_CheckBox4dCompleteTable->setChecked(false);
   }
 
 
   for (unsigned int t = 0; t < image->GetTimeSteps(); t++)
   {
     this->m_Controls->m_StatisticsTable->setHorizontalHeaderItem(t,
         new QTableWidgetItem(QString::number(t)));
 
     if (statistics.at(t)->GetMaxIndex().size()==3)
     {
       mitk::Point3D index, max, min;
       index[0] = statistics.at(t)->GetMaxIndex()[0];
       index[1] = statistics.at(t)->GetMaxIndex()[1];
       index[2] = statistics.at(t)->GetMaxIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, max);
       this->m_WorldMaxList.push_back(max);
       index[0] = statistics.at(t)->GetMinIndex()[0];
       index[1] = statistics.at(t)->GetMinIndex()[1];
       index[2] = statistics.at(t)->GetMinIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, min);
       this->m_WorldMinList.push_back(min);
     }
 
     auto statisticsVector = AssembleStatisticsIntoVector(statistics.at(t).GetPointer(), image);
 
     unsigned int count = 0;
     for (const auto& entry : statisticsVector) {
       auto item = new QTableWidgetItem(entry);
       this->m_Controls->m_StatisticsTable->setItem(count, t, item);
       count++;
     }
 
     }
 
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 
   // make sure the current timestep's column is highlighted (and the correct histogram is displayed)
   unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
       GetPos();
   mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(),
       t);
   this->OnTimeChanged(timeEvent);
 
   t = std::min(image->GetTimeSteps() - 1, t);
 
   // See bug 18340
   /*QString hotspotMean; hotspotMean.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMean(), 0, 'f', decimals));
   hotspotMean += " (";
   for (int i=0; i<s[t].GetHotspotIndex().size(); i++)
   {
   hotspotMean += QString::number(s[t].GetHotspotIndex()[i]);
   if (i<s[t].GetHotspotIndex().size()-1)
   hotspotMean += ",";
   }
   hotspotMean += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 7, t, new QTableWidgetItem( hotspotMean ) );
 
   QString hotspotMax; hotspotMax.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMax(), 0, 'f', decimals));
   hotspotMax += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMaxIndex().size(); i++)
   {
   hotspotMax += QString::number(s[t].GetHotspotStatistics().GetMaxIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMaxIndex().size()-1)
   hotspotMax += ",";
   }
   hotspotMax += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 8, t, new QTableWidgetItem( hotspotMax ) );
 
   QString hotspotMin; hotspotMin.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMin(), 0, 'f', decimals));
   hotspotMin += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMinIndex().size(); i++)
   {
   hotspotMin += QString::number(s[t].GetHotspotStatistics().GetMinIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMinIndex().size()-1)
   hotspotMin += ",";
   }
   hotspotMin += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 9, t, new QTableWidgetItem( hotspotMin ) );*/
 }
 
 std::vector<QString> QmitkImageStatisticsView::AssembleStatisticsIntoVector(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics, mitk::Image::ConstPointer image, bool noVolumeDefined) const
 {
   std::vector<QString> result;
 
   unsigned int decimals = 2;
 
   //statistics of higher order should have 5 decimal places because they used to be very small
   unsigned int decimalsHigherOrderStatistics = 5;
 
   if (image->GetPixelType().GetComponentType() == itk::ImageIOBase::DOUBLE || image->GetPixelType().GetComponentType() == itk::ImageIOBase::FLOAT)
   {
     decimals = 5;
   }
 
   result.push_back(GetFormattedString(statistics->GetMean(), decimals));
   result.push_back(GetFormattedString(statistics->GetMedian(), decimals));
   result.push_back(GetFormattedString(statistics->GetStd(), decimals));
   result.push_back(GetFormattedString(statistics->GetRMS(), decimals));
   result.push_back(GetFormattedString(statistics->GetMax(), decimals) + " " + GetFormattedIndex(statistics->GetMaxIndex()));
   result.push_back(GetFormattedString(statistics->GetMin(), decimals) + " " + GetFormattedIndex(statistics->GetMinIndex()));
   //to prevent large negative values of empty image statistics
   if (statistics->GetN() != std::numeric_limits<long>::min()) {
     result.push_back(GetFormattedString(statistics->GetN(), 0));
 
     const mitk::BaseGeometry *geometry = image->GetGeometry();
     if (geometry != NULL && !noVolumeDefined)
   {
       const mitk::Vector3D &spacing = image->GetGeometry()->GetSpacing();
       double volume = spacing[0] * spacing[1] * spacing[2] * static_cast<double>(statistics->GetN());
       result.push_back(GetFormattedString(volume, decimals));
   }
     else {
       result.push_back("NA");
   }
   }
   else {
     result.push_back("NA");
     result.push_back("NA");
   }
 
   result.push_back(GetFormattedString(statistics->GetSkewness(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetKurtosis(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetUniformity(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetEntropy(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetMPP(), decimals));
   result.push_back(GetFormattedString(statistics->GetUPP(), decimalsHigherOrderStatistics));
 
   return result;
 }
 
 void QmitkImageStatisticsView::FillLinearProfileStatisticsTableView(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics,
   const mitk::Image *image)
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
 
   m_PlanarFigureStatistics = this->AssembleStatisticsIntoVector(statistics, image, true);
 
   for (unsigned int i = 0; i< m_PlanarFigureStatistics.size(); i++)
   {
     this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem(m_PlanarFigureStatistics[i] ));
   }
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 }
 
 void QmitkImageStatisticsView::InvalidateStatisticsTableView()
 {
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
 
   for ( int i = 0; i < this->m_Controls->m_StatisticsTable->rowCount(); ++i )
   {
     {
       this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem( "NA" ) );
     }
   }
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(STAT_TABLE_BASE_HEIGHT);
 }
 
 void QmitkImageStatisticsView::Activated()
 {
 }
 
 void QmitkImageStatisticsView::Deactivated()
 {
 }
 
 void QmitkImageStatisticsView::Visible()
 {
   m_Visible = true;
 
   mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
   if (renderWindow)
   {
     itk::ReceptorMemberCommand<QmitkImageStatisticsView>::Pointer cmdTimeEvent =
         itk::ReceptorMemberCommand<QmitkImageStatisticsView>::New();
     cmdTimeEvent->SetCallbackFunction(this, &QmitkImageStatisticsView::OnTimeChanged);
 
     // It is sufficient to add the observer to the axial render window since the GeometryTimeEvent
     // is always triggered by all views.
     m_TimeObserverTag = renderWindow->GetQmitkRenderWindow("axial")->
         GetSliceNavigationController()->
         AddObserver(mitk::SliceNavigationController::GeometryTimeEvent(nullptr, 0), cmdTimeEvent);
   }
 
   if (m_DataNodeSelectionChanged)
   {
     if (this->IsCurrentSelectionValid())
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->SelectionChanged(this->GetDataManagerSelection());
     }
     m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::Hidden()
 {
   m_Visible = false;
 
   // The slice navigation controller observer is removed here instead of in the destructor.
   // If it was called in the destructor, the application would freeze because the view's
   // destructor gets called after the render windows have been destructed.
   if ( m_TimeObserverTag != 0 )
   {
     mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
     if (renderWindow)
     {
       renderWindow->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->
           RemoveObserver( m_TimeObserverTag );
     }
     m_TimeObserverTag = 0;
   }
 }
 
 void QmitkImageStatisticsView::SetFocus()
 {
 }
 
 std::map<double, double> QmitkImageStatisticsView::ConvertHistogramToMap(itk::Statistics::Histogram<double>::ConstPointer histogram) const
 {
   std::map<double, double> histogramMap;
 
   auto endIt = histogram->End();
   auto it = histogram->Begin();
 
   // generating Lists of measurement and frequencies
   for (; it != endIt; ++it)
   {
     double frequency = it.GetFrequency();
     double measurement = it.GetMeasurementVector()[0];
     histogramMap.emplace(measurement, frequency);
   }
 
   return histogramMap;
 }
 
 std::vector<double> QmitkImageStatisticsView::ConvertIntensityProfileToVector(mitk::IntensityProfile::ConstPointer intensityProfile) const
 {
   std::vector<double> intensityProfileList;
   auto end = intensityProfile->End();
 
   for (auto it = intensityProfile->Begin(); it != end; ++it)
   {
     intensityProfileList.push_back(it.GetMeasurementVector()[0]);
   }
   return intensityProfileList;
 }
 
 QString QmitkImageStatisticsView::GetFormattedString(double value, unsigned int decimals) const
 {
   typedef mitk::ImageStatisticsCalculator::StatisticsContainer::RealType RealType;
   RealType maxVal = std::numeric_limits<RealType>::max();
 
   if (value == maxVal)
   {
     return QString("NA");
   }
   else
   {
     return QString("%1").arg(value, 0, 'f', decimals);
   }
 }
 
 QString QmitkImageStatisticsView::GetFormattedIndex(const vnl_vector<int>& vector) const
 {
   if (vector.empty()) {
     return QString();
   }
   QString formattedIndex("(");
   for (const auto& entry : vector)
   {
     formattedIndex += QString::number(entry);
     formattedIndex += ",";
   }
   formattedIndex.chop(1);
   formattedIndex += ")";
   return formattedIndex;
 }