diff --git a/Modules/DiffusionImaging/DiffusionIO/mitkPeakImageMapper2D.cpp b/Modules/DiffusionImaging/DiffusionIO/mitkPeakImageMapper2D.cpp
index f12d2b0feb..796e8992b8 100644
--- a/Modules/DiffusionImaging/DiffusionIO/mitkPeakImageMapper2D.cpp
+++ b/Modules/DiffusionImaging/DiffusionIO/mitkPeakImageMapper2D.cpp
@@ -1,239 +1,240 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include "mitkPeakImageMapper2D.h"
 #include "mitkBaseRenderer.h"
 #include "mitkDataNode.h"
 #include <vtkActor.h>
 #include <vtkOpenGLPolyDataMapper.h>
 #include <vtkOpenGLHelper.h>
 #include <vtkShaderProgram.h>
 #include <vtkPlane.h>
 #include <vtkPolyData.h>
 #include <vtkPointData.h>
 #include <vtkProperty.h>
 #include <vtkLookupTable.h>
 #include <vtkPoints.h>
 #include <vtkCamera.h>
 #include <vtkPolyLine.h>
 #include <vtkRenderer.h>
 #include <vtkCellArray.h>
 #include <vtkMatrix4x4.h>
 #include <vtkTubeFilter.h>
 #include <mitkPlaneGeometry.h>
 #include <mitkSliceNavigationController.h>
 #include <mitkCoreServices.h>
 
 class vtkPeakShaderCallback : public vtkCommand
 {
 public:
   static vtkPeakShaderCallback *New()
   {
     return new vtkPeakShaderCallback;
   }
   mitk::BaseRenderer *renderer;
   mitk::DataNode *node;
 
   void Execute(vtkObject *, unsigned long, void*cbo) override
   {
     vtkOpenGLHelper *cellBO = reinterpret_cast<vtkOpenGLHelper*>(cbo);
 
 
     mitk::Image* image = dynamic_cast<mitk::Image*>(node->GetData());
     mitk::Vector3D spacing = image->GetGeometry()->GetSpacing();
 
     float minSpacing = 1;
     if(spacing[0]<spacing[1] && spacing[0]<spacing[2])
       minSpacing = spacing[0];
     else if (spacing[1] < spacing[2])
       minSpacing = spacing[1];
     else
       minSpacing = spacing[2];
 
     float peakOpacity;
     node->GetOpacity(peakOpacity, nullptr);
 
     cellBO->Program->SetUniformf("peakOpacity", peakOpacity);
     cellBO->Program->SetUniformf("clippingPlaneThickness", minSpacing/2);
 
     if (this->renderer)
     {
       //get information about current position of views
       mitk::SliceNavigationController::Pointer sliceContr = renderer->GetSliceNavigationController();
       mitk::PlaneGeometry::ConstPointer planeGeo = sliceContr->GetCurrentPlaneGeometry();
 
       //generate according cutting planes based on the view position
       float planeNormal[3];
       planeNormal[0] = planeGeo->GetNormal()[0];
       planeNormal[1] = planeGeo->GetNormal()[1];
       planeNormal[2] = planeGeo->GetNormal()[2];
 
       float tmp1 = planeGeo->GetOrigin()[0] * planeNormal[0];
       float tmp2 = planeGeo->GetOrigin()[1] * planeNormal[1];
       float tmp3 = planeGeo->GetOrigin()[2] * planeNormal[2];
       float thickness = tmp1 + tmp2 + tmp3; //attention, correct normalvector
 
       float* a = new float[4];
       for (int i = 0; i < 3; ++i)
         a[i] = planeNormal[i];
 
       a[3] = thickness;
       cellBO->Program->SetUniform4f("slicingPlane", a);
     }
   }
 
   vtkPeakShaderCallback() { this->renderer = 0; }
 };
 
 
 
 mitk::PeakImageMapper2D::PeakImageMapper2D()
 {
   m_lut = vtkLookupTable::New();
   m_lut->Build();
 }
 
 mitk::PeakImageMapper2D::~PeakImageMapper2D()
 {
 }
 
 
 mitk::PeakImage* mitk::PeakImageMapper2D::GetInput()
 {
   return dynamic_cast< mitk::PeakImage * > ( GetDataNode()->GetData() );
 }
 
 void mitk::PeakImageMapper2D::UpdateVtkTransform(mitk::BaseRenderer *)
 {
   // don't apply transform since the peak polydata is already in world coordinates.
   return;
 }
 
 void mitk::PeakImageMapper2D::Update(mitk::BaseRenderer * renderer)
 {
   mitk::DataNode* node = this->GetDataNode();
   if (node == nullptr)
     return;
 
   bool visible = true;
   node->GetVisibility(visible, renderer, "visible");
   if ( !visible )
     return;
 
   this->GenerateDataForRenderer( renderer );
 }
 
 void mitk::PeakImageMapper2D::UpdateShaderParameter(mitk::BaseRenderer *)
 {
   // see new vtkPeakShaderCallback
 }
 
 // vtkActors and Mappers are feeded here
 void mitk::PeakImageMapper2D::GenerateDataForRenderer(mitk::BaseRenderer *renderer)
 {
   mitk::PeakImage* peakImage = this->GetInput();
 
   //the handler of local storage gets feeded in this method with requested data for related renderwindow
   FBXLocalStorage *localStorage = m_LocalStorageHandler.GetLocalStorage(renderer);
 
   vtkSmartPointer<vtkPolyData> polyData = peakImage->GetPolyData();
   if (polyData == nullptr)
     return;
 
   localStorage->m_Mapper->ScalarVisibilityOn();
   localStorage->m_Mapper->SetScalarModeToUsePointFieldData();
   localStorage->m_Mapper->SetLookupTable(m_lut);  //apply the properties after the slice was set
 //  localStorage->m_PointActor->GetProperty()->SetOpacity(0.999);
   localStorage->m_Mapper->SelectColorArray("FIBER_COLORS");
 
   localStorage->m_Mapper->SetInputData(polyData);
   localStorage->m_Mapper->SetVertexShaderCode(
         "//VTK::System::Dec\n"
         "attribute vec4 vertexMC;\n"
 
         "//VTK::Normal::Dec\n"
         "uniform mat4 MCDCMatrix;\n"
 
         "//VTK::Color::Dec\n"
 
         "varying vec4 positionWorld;\n"
         "varying vec4 colorVertex;\n"
 
         "void main(void)\n"
         "{\n"
         "  colorVertex = scalarColor;\n"
         "  positionWorld = vertexMC;\n"
         "  gl_Position = MCDCMatrix * vertexMC;\n"
         "}\n"
         );
   localStorage->m_Mapper->SetFragmentShaderCode(
         "//VTK::System::Dec\n"  // always start with this line
         "//VTK::Output::Dec\n"  // always have this line in your FS
         "uniform vec4 slicingPlane;\n"
         "uniform float clippingPlaneThickness;\n"
         "uniform float peakOpacity;\n"
         "varying vec4 positionWorld;\n"
         "varying vec4 colorVertex;\n"
+        "out vec4 out_Color;\n"
 
         "void main(void)\n"
         "{\n"
         "  float r1 = dot(positionWorld.xyz, slicingPlane.xyz) - slicingPlane.w;\n"
 
         "  if (abs(r1) >= clippingPlaneThickness)\n"
         "    discard;\n"
-        "  gl_FragColor = vec4(colorVertex.xyz,peakOpacity);\n"
+        "  out_Color = vec4(colorVertex.xyz,peakOpacity);\n"
         "}\n"
         );
 
   vtkSmartPointer<vtkPeakShaderCallback> myCallback = vtkSmartPointer<vtkPeakShaderCallback>::New();
   myCallback->renderer = renderer;
   myCallback->node = this->GetDataNode();
   localStorage->m_Mapper->AddObserver(vtkCommand::UpdateShaderEvent,myCallback);
 
   localStorage->m_PointActor->SetMapper(localStorage->m_Mapper);
   localStorage->m_PointActor->GetProperty()->ShadingOn();
 
   float linewidth = 1.0;
   this->GetDataNode()->GetFloatProperty("shape.linewidth",linewidth);
   localStorage->m_PointActor->GetProperty()->SetLineWidth(linewidth);
 
   // We have been modified => save this for next Update()
   localStorage->m_LastUpdateTime.Modified();
 }
 
 
 vtkProp* mitk::PeakImageMapper2D::GetVtkProp(mitk::BaseRenderer *renderer)
 {
   this->Update(renderer);
   return m_LocalStorageHandler.GetLocalStorage(renderer)->m_PointActor;
 }
 
 
 void mitk::PeakImageMapper2D::SetDefaultProperties(mitk::DataNode* node, mitk::BaseRenderer* renderer, bool overwrite)
 {
   Superclass::SetDefaultProperties(node, renderer, overwrite);
 
   //add other parameters to propertylist
   node->AddProperty( "color", mitk::ColorProperty::New(1.0,1.0,1.0), renderer, overwrite);
   node->AddProperty( "shape.linewidth", mitk::FloatProperty::New(1.0), renderer, overwrite);
 }
 
 
 mitk::PeakImageMapper2D::FBXLocalStorage::FBXLocalStorage()
 {
   m_PointActor = vtkSmartPointer<vtkActor>::New();
   m_Mapper = vtkSmartPointer<MITKPeakImageMapper2D_POLYDATAMAPPER>::New();
 }
diff --git a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
index 366e1d3577..3a4b97baa2 100644
--- a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
+++ b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
@@ -1,1295 +1,1295 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include "QmitkImageStatisticsView.h"
 
 // Qt includes
 #include <QClipboard>
 #include <QScrollBar>
 #include <QVector>
 
 // berry includes
 #include <berryIWorkbenchPage.h>
 
 // mitk includes
 #include <mitkNodePredicateDataType.h>
 #include <mitkNodePredicateOr.h>
 #include <mitkPlanarFigureInteractor.h>
 #include <mitkImageTimeSelector.h>
 #include <QmitkRenderWindow.h>
 #include <QmitkChartWidget.h>
 #include <mitkImageCast.h>
 
 // itk includes
 #include "itksys/SystemTools.hxx"
 #include "itkImageRegionConstIteratorWithIndex.h"
 
 #include <limits>
 
 //blueberry includes
 #include <berryWorkbenchPlugin.h>
 #include <berryQtPreferences.h>
 
 const std::string QmitkImageStatisticsView::VIEW_ID = "org.mitk.views.imagestatistics";
 const int QmitkImageStatisticsView::STAT_TABLE_BASE_HEIGHT = 180;
 
 QmitkImageStatisticsView::QmitkImageStatisticsView(QObject* /*parent*/, const char* /*name*/)
 : m_Controls( nullptr ),
   m_SelectedImage( nullptr ),
   m_SelectedImageMask( nullptr ),
   m_SelectedPlanarFigure( nullptr ),
   m_ImageObserverTag( -1 ),
   m_ImageMaskObserverTag( -1 ),
   m_PlanarFigureObserverTag( -1 ),
   m_TimeObserverTag( -1 ),
   m_CurrentStatisticsValid( false ),
   m_StatisticsUpdatePending( false ),
   m_DataNodeSelectionChanged ( false ),
   m_Visible(false)
 {
   this->m_CalculationThread = new QmitkImageStatisticsCalculationThread;
 }
 
 QmitkImageStatisticsView::~QmitkImageStatisticsView()
 {
   if ( m_SelectedImage != nullptr )
     m_SelectedImage->RemoveObserver( m_ImageObserverTag );
   if ( m_SelectedImageMask != nullptr )
     m_SelectedImageMask->RemoveObserver( m_ImageMaskObserverTag );
   if ( m_SelectedPlanarFigure != nullptr )
     m_SelectedPlanarFigure->RemoveObserver( m_PlanarFigureObserverTag );
 
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
   delete this->m_CalculationThread;
 }
 
 
 void QmitkImageStatisticsView::CreateQtPartControl(QWidget *parent)
 {
   if (m_Controls == nullptr)
   {
     m_Controls = new Ui::QmitkImageStatisticsViewControls;
     m_Controls->setupUi(parent);
     CreateConnections();
 
     m_Controls->m_ErrorMessageLabel->hide();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_Controls->m_BinSizeFrame->setEnabled(false);
     #if QT_VERSION < QT_VERSION_CHECK(5, 10, 0)
       m_Controls->m_StatisticsWidgetStack->setVisible(false);
       m_Controls->label_HistogramIsInvisibleWarning->setEnabled(true);
       m_Controls->label_HistogramIsInvisibleWarning->setVisible(true);
       m_Controls->label_HistogramIsInvisibleWarning->setText("<font color='red'>Histogram is not visible because Qt 5.10 is required. You can use the button <i>Copy to Clipboard</i> below to retrieve values.</font>");
       m_Controls->groupBox_plot->setVisible(false);
     #else
       m_Controls->label_HistogramIsInvisibleWarning->setVisible(false);
     #endif
 
   }
 }
 
 void QmitkImageStatisticsView::OnPageSuccessfullyLoaded()
 {
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   QString styleName = m_StylePref->Get(berry::QtPreferences::QT_STYLE_NAME, "");
 
   if (styleName == ":/org.blueberry.ui.qt/darkstyle.qss")
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::darkstyle);
   }
   else
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::lightstyle);
   }
 }
 
 void QmitkImageStatisticsView::CreateConnections()
 {
   if ( m_Controls )
   {
     connect( (QObject*)(this->m_Controls->m_ButtonCopyHistogramToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardHistogramButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_ButtonCopyStatisticsToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardStatisticsButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_IgnoreZerosCheckbox), SIGNAL(clicked()),(QObject*) this, SLOT(OnIgnoreZerosCheckboxClicked()) );
     connect( (QObject*) this->m_CalculationThread, SIGNAL(finished()),this, SLOT( OnThreadedStatisticsCalculationEnds()),Qt::QueuedConnection);
     connect( (QObject*) this, SIGNAL(StatisticsUpdate()),this, SLOT( RequestStatisticsUpdate()), Qt::QueuedConnection);
     connect( (QObject*) this->m_Controls->m_StatisticsTable, SIGNAL(cellDoubleClicked(int,int)),this, SLOT( JumpToCoordinates(int,int)) );
     connect((QObject*)(this->m_Controls->m_barRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnBarRadioButtonSelected()));
     connect((QObject*)(this->m_Controls->m_lineRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnLineRadioButtonSelected()));
     connect( (QObject*) (this->m_Controls->m_HistogramNBinsSpinbox), SIGNAL(editingFinished()), this, SLOT(OnHistogramNBinsCheckBoxValueChanged()));
     connect((QObject*)(this->m_Controls->m_UseDefaultNBinsCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnDefaultNBinsSpinBoxChanged()));
     connect((QObject*)(this->m_Controls->m_ShowSubchartCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnShowSubchartBoxChanged()));
     connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   }
 }
 
 void QmitkImageStatisticsView::OnDefaultNBinsSpinBoxChanged()
 {
   if (this->m_Controls->m_UseDefaultNBinsCheckBox->isChecked()) {
     m_Controls->m_HistogramNBinsSpinbox->setValue(100);
     this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
     m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   }
   m_Controls->m_BinSizeFrame->setEnabled(!m_Controls->m_UseDefaultNBinsCheckBox->isChecked());
 
   this->UpdateStatistics();
 
 }
 
 void QmitkImageStatisticsView::OnShowSubchartBoxChanged()
 {
   bool showSubchart = this->m_Controls->m_ShowSubchartCheckBox->isChecked();
   this->m_Controls->m_JSHistogram->Reload(showSubchart);
 }
 
 
 void QmitkImageStatisticsView::OnBarRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::bar);
 }
 
 void QmitkImageStatisticsView::OnLineRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::line);
 }
 
 void QmitkImageStatisticsView::PartClosed(const berry::IWorkbenchPartReference::Pointer& )
 {
 }
 
 void QmitkImageStatisticsView::OnTimeChanged(const itk::EventObject& e)
 {
   if (this->m_SelectedDataNodes.isEmpty() || this->m_SelectedImage == nullptr)
     return;
 
   const mitk::SliceNavigationController::GeometryTimeEvent* timeEvent =
       dynamic_cast<const mitk::SliceNavigationController::GeometryTimeEvent*>(&e);
   assert(timeEvent != nullptr);
   int timestep = timeEvent->GetPos();
 
   if (this->m_SelectedImage->GetTimeSteps() > 1)
   {
     for (int x = 0; x < this->m_Controls->m_StatisticsTable->columnCount(); x++)
     {
       for (int y = 0; y < this->m_Controls->m_StatisticsTable->rowCount(); y++)
       {
         QTableWidgetItem* item = this->m_Controls->m_StatisticsTable->item(y, x);
         if (item == nullptr)
           break;
 
         if (x == timestep)
         {
           item->setBackgroundColor(Qt::yellow);
         }
         else
         {
           if (y % 2 == 0)
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().base());
           else
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().alternateBase());
         }
       }
     }
 
     this->m_Controls->m_StatisticsTable->viewport()->update();
   }
 
   if ((this->m_SelectedImage->GetTimeSteps() == 1 && timestep == 0) ||
       this->m_SelectedImage->GetTimeSteps() > 1)
   {
     // display histogram for selected timestep
     this->m_Controls->m_JSHistogram->Clear();
     QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer histogram =
         (QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer)this->m_CalculationThread->GetTimeStepHistogram(timestep);
 
     if (histogram.IsNotNull())
     {
       bool closedFigure = this->m_CalculationThread->GetStatisticsUpdateSuccessFlag();
 
       if (closedFigure)
       {
 
         auto imageNameLabel = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         this->m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageNameLabel);
         if (this->m_Controls->m_lineRadioButton->isChecked())
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::line);
         }
         else
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::bar);
         }
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Grey value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         this->m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
       }
     }
   }
 }
 
 void QmitkImageStatisticsView::JumpToCoordinates(int row ,int col)
 {
   if(m_SelectedDataNodes.isEmpty())
   {
     MITK_WARN("QmitkImageStatisticsView") << "No data node selected for statistics calculation." ;
     return;
   }
 
   mitk::Point3D world;
   if (row==5 && !m_WorldMinList.empty())
     world = m_WorldMinList[col];
   else if (row==4 && !m_WorldMaxList.empty())
     world = m_WorldMaxList[col];
   else
     return;
 
   mitk::IRenderWindowPart* part = this->GetRenderWindowPart();
   if (part)
   {
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("sagittal")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("coronal")->GetSliceNavigationController()->SelectSliceByPoint(world);
 
     mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(), col);
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SetGeometryTime(timeEvent);
   }
 }
 
 void QmitkImageStatisticsView::OnIgnoreZerosCheckboxClicked()
 {
   emit StatisticsUpdate();
 }
 
 void QmitkImageStatisticsView::OnClipboardHistogramButtonClicked()
 {
   if (!m_CurrentStatisticsValid)
   {
     QApplication::clipboard()->clear();
   }
 
   if (m_SelectedPlanarFigure == nullptr)
   {
     const unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
     typedef mitk::ImageStatisticsCalculator::HistogramType HistogramType;
     const HistogramType *histogram = this->m_CalculationThread->GetTimeStepHistogram(t).GetPointer();
 
     QString clipboard("Measurement \t Frequency\n");
     for (HistogramType::ConstIterator it = histogram->Begin();
       it != histogram->End();
       ++it)
     {
       clipboard = clipboard.append("%L1 \t %L2\n")
         .arg(it.GetMeasurementVector()[0], 0, 'f', 2)
         .arg(it.GetFrequency());
     }
 
     QApplication::clipboard()->setText(
       clipboard, QClipboard::Clipboard);
   }
   //If a (non-closed) PlanarFigure is selected, display a line profile widget
   else if (m_SelectedPlanarFigure != nullptr)
   {
     QString clipboard("Pixel \t Intensity\n");
-    for (auto i = 0; i < m_IntensityProfileList.size(); i++)
+    for (unsigned int i = 0; i < m_IntensityProfileList.size(); i++)
     {
       clipboard =
         clipboard.append("%L1 \t %L2\n").arg(QString::number(i)).arg(QString::number(m_IntensityProfileList.at(i)));
     }
     QApplication::clipboard()->setText(clipboard, QClipboard::Clipboard);
   }
 }
 
 void QmitkImageStatisticsView::OnClipboardStatisticsButtonClicked()
 {
   QLocale tempLocal;
   QLocale::setDefault(QLocale(QLocale::English, QLocale::UnitedStates));
   if ( m_CurrentStatisticsValid && !( m_SelectedPlanarFigure != nullptr))
    {
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics =
       this->m_CalculationThread->GetStatisticsData();
 
     // Set time borders for for loop ;)
     unsigned int startT, endT;
     if(this->m_Controls->m_CheckBox4dCompleteTable->checkState()==Qt::CheckState::Unchecked)
     {
         startT = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
           GetPos();
         endT = startT+1;
     }
     else
     {
         startT = 0;
         endT = statistics.size();
     }
     QVector< QVector<QString> > statisticsTable;
     QStringList headline{ "Timestep", "Mean", "Median", "StdDev", "RMS", "Max", "Min", "NumberOfVoxels", "Skewness", "Kurtosis", "Uniformity", "Entropy", "MPP", "UPP", "V [mm³]" };
 
     for(int i=0;i<headline.size();i++)
     {
         QVector<QString> row;
         row.append(headline.at(i));
         statisticsTable.append(row);
     }
 
     // Fill Table
     for(unsigned int t=startT;t<endT;t++)
     {
         // Copy statistics to clipboard ("%Ln" will use the default locale for
         // number formatting)
         QStringList value;
         value << QString::number(t)
               << QString::number(statistics[t]->GetMean())
               << QString::number(statistics[t]->GetMedian())
               << QString::number(statistics[t]->GetStd())
               << QString::number(statistics[t]->GetRMS())
               << QString::number(statistics[t]->GetMax())
               << QString::number(statistics[t]->GetMin())
               << QString::number(statistics[t]->GetN())
               << QString::number(statistics[t]->GetSkewness())
               << QString::number(statistics[t]->GetKurtosis())
               << QString::number(statistics[t]->GetUniformity())
               << QString::number(statistics[t]->GetEntropy())
               << QString::number(statistics[t]->GetMPP())
               << QString::number(statistics[t]->GetUPP())
               << QString::number(m_Controls->m_StatisticsTable->item(7, 0)->data(Qt::DisplayRole).toDouble());
 
          for(int z=0;z<value.size();z++)
          {
              statisticsTable[z].append(value.at(z));
          }
     }
 
     // Create output string
     QString clipboard;
     for(int i=0;i<statisticsTable.size();i++)
     {
         for(int t=0;t<statisticsTable.at(i).size();t++)
         {
             clipboard.append(statisticsTable.at(i).at(t));
             clipboard.append("\t");
         }
         clipboard.append("\n");
     }
     QApplication::clipboard()->setText(clipboard, QClipboard::Clipboard);
   }
   else
   {
     QApplication::clipboard()->clear();
   }
   QLocale::setDefault(tempLocal);
 }
 
 void QmitkImageStatisticsView::OnSelectionChanged( berry::IWorkbenchPart::Pointer /*part*/,
     const QList<mitk::DataNode::Pointer> &nodes )
 {
   if (this->m_Visible)
   {
     this->SelectionChanged( nodes );
   }
   else
   {
     this->m_DataNodeSelectionChanged = true;
   }
 }
 
 void QmitkImageStatisticsView::SelectionChanged(const QList<mitk::DataNode::Pointer> &selectedNodes)
 {
   //Clear Histogram if data node is deselected
   m_Controls->m_JSHistogram->Clear();
 
   if( this->m_StatisticsUpdatePending )
   {
     this->m_DataNodeSelectionChanged = true;
     return; // not ready for new data now!
   }
 
   if (selectedNodes.size() == this->m_SelectedDataNodes.size())
   {
     int i = 0;
     for (; i < selectedNodes.size(); ++i)
     {
       if (selectedNodes.at(i) != this->m_SelectedDataNodes.at(i))
       {
         break;
       }
     }
     // node selection did not change
     if (i == selectedNodes.size()) return;
   }
 
   //reset the feature image and image mask field
   m_Controls->m_SelectedFeatureImageLabel->setText("None");
   m_Controls->m_SelectedMaskLabel->setText("None");
 
   this->ReinitData();
   if (selectedNodes.isEmpty())
   {
     DisableHistogramGUIElements();
   }
   else
   {
     EnableHistogramGUIElements();
     ResetHistogramGUIElementsToDefault();
   }
   if(selectedNodes.size() == 1 || selectedNodes.size() == 2)
   {
     bool isBinary = false;
     selectedNodes.value(0)->GetBoolProperty("binary",isBinary);
     mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
     isBinary |= isLabelSet->CheckNode(selectedNodes.value(0));
     if(isBinary)
     {
       EnableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
     }
     for (int i= 0; i< selectedNodes.size(); ++i)
     {
       this->m_SelectedDataNodes.push_back(selectedNodes.at(i));
     }
     this->m_DataNodeSelectionChanged = false;
     this->m_Controls->m_ErrorMessageLabel->setText( "" );
     this->m_Controls->m_ErrorMessageLabel->hide();
     emit StatisticsUpdate();
   }
   else
   {
     this->m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::DisableHistogramGUIElements()
 {
   m_Controls->m_InfoLabel->setText("");
   m_Controls->groupBox_histogram->setEnabled(false);
   m_Controls->groupBox_statistics->setEnabled(false);
 }
 
 void QmitkImageStatisticsView::ResetHistogramGUIElementsToDefault()
 {
   m_Controls->m_barRadioButton->setChecked(true);
   m_Controls->m_HistogramNBinsSpinbox->setValue(100);
   m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   m_Controls->m_UseDefaultNBinsCheckBox->setChecked(true);
   m_Controls->m_ShowSubchartCheckBox->setChecked(true);
   m_Controls->m_BinSizeFrame->setEnabled(false);
   m_Controls->m_barRadioButton->setEnabled(true);
   m_Controls->m_lineRadioButton->setEnabled(true);
   m_Controls->m_HistogramNBinsSpinbox->setEnabled(true);
   this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
 }
 
 void QmitkImageStatisticsView::EnableHistogramGUIElements()
 {
   m_Controls->groupBox_histogram->setEnabled(true);
   m_Controls->groupBox_plot->setEnabled(true);
   m_Controls->groupBox_statistics->setEnabled(true);
 }
 
 void QmitkImageStatisticsView::ReinitData()
 {
   while( this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if(this->m_SelectedImage != nullptr)
   {
     this->m_SelectedImage->RemoveObserver( this->m_ImageObserverTag);
     this->m_SelectedImage = nullptr;
   }
   if(this->m_SelectedImageMask != nullptr)
   {
     this->m_SelectedImageMask->RemoveObserver( this->m_ImageMaskObserverTag);
     this->m_SelectedImageMask = nullptr;
   }
   if(this->m_SelectedPlanarFigure != nullptr)
   {
     this->m_SelectedPlanarFigure->RemoveObserver( this->m_PlanarFigureObserverTag);
     this->m_SelectedPlanarFigure = nullptr;
   }
   this->m_SelectedDataNodes.clear();
   this->m_StatisticsUpdatePending = false;
 
   m_Controls->m_ErrorMessageLabel->setText( "" );
   m_Controls->m_ErrorMessageLabel->hide();
   this->InvalidateStatisticsTableView();
   m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
 }
 
 void QmitkImageStatisticsView::OnThreadedStatisticsCalculationEnds()
 {
   m_Controls->m_ErrorMessageLabel->setText("");
   m_Controls->m_ErrorMessageLabel->hide();
   this->WriteStatisticsToGUI();
 }
 
 void QmitkImageStatisticsView::UpdateStatistics()
 {
   mitk::IRenderWindowPart* renderPart = this->GetRenderWindowPart();
   if ( renderPart == nullptr )
   {
     this->m_StatisticsUpdatePending =  false;
     return;
   }
   m_WorldMinList.clear();
   m_WorldMaxList.clear();
 
   // classify selected nodes
   mitk::NodePredicateDataType::Pointer isImage = mitk::NodePredicateDataType::New("Image");
   mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
   mitk::NodePredicateOr::Pointer imagePredicate = mitk::NodePredicateOr::New(isImage, isLabelSet);
 
   std::string maskName;
   std::string maskType;
   std::string featureImageName;
   unsigned int maskDimension = 0;
 
   // reset data from last run
   ITKCommandType::Pointer changeListener = ITKCommandType::New();
   changeListener->SetCallbackFunction( this, &QmitkImageStatisticsView::SelectedDataModified );
 
   mitk::DataNode::Pointer planarFigureNode;
   for( int i= 0 ; i < this->m_SelectedDataNodes.size(); ++i)
   {
     mitk::PlanarFigure::Pointer planarFig = dynamic_cast<mitk::PlanarFigure*>(this->m_SelectedDataNodes.at(i)->GetData());
     if( imagePredicate->CheckNode(this->m_SelectedDataNodes.at(i)) )
     {
       bool isMask = false;
       this->m_SelectedDataNodes.at(i)->GetPropertyValue("binary", isMask);
       isMask |= isLabelSet->CheckNode(this->m_SelectedDataNodes.at(i));
 
       if( this->m_SelectedImageMask == nullptr && isMask)
       {
         this->m_SelectedImageMask = dynamic_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
         this->m_ImageMaskObserverTag = this->m_SelectedImageMask->AddObserver(itk::ModifiedEvent(), changeListener);
 
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = m_SelectedImageMask->GetNameOfClass();
         maskDimension = 3;
       }
       else if( !isMask )
       {
         if(this->m_SelectedImage == nullptr)
         {
           this->m_SelectedImage = static_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
           this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
         }
         featureImageName = this->m_SelectedDataNodes.at(i)->GetName();
       }
     }
     else if (planarFig.IsNotNull())
     {
       if(this->m_SelectedPlanarFigure == nullptr)
       {
         this->m_SelectedPlanarFigure = planarFig;
         this->m_PlanarFigureObserverTag  =
             this->m_SelectedPlanarFigure->AddObserver(mitk::EndInteractionPlanarFigureEvent(), changeListener);
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = this->m_SelectedPlanarFigure->GetNameOfClass();
         maskDimension = 2;
         planarFigureNode = m_SelectedDataNodes.at(i);
       }
     }
     else
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Invalid data node type!</font>");
       m_Controls->m_ErrorMessageLabel->show();
     }
   }
 
   if(maskName == "")
   {
     maskName = "None";
     maskType = "";
     maskDimension = 0;
   }
 
   if(featureImageName == "")
   {
     featureImageName = "None";
   }
 
   if (m_SelectedPlanarFigure != nullptr && m_SelectedImage == nullptr)
   {
     mitk::DataStorage::SetOfObjects::ConstPointer parentSet = this->GetDataStorage()->GetSources(planarFigureNode);
     for (unsigned int i=0; i<parentSet->Size(); i++)
     {
       mitk::DataNode::Pointer node = parentSet->ElementAt(i);
       if( imagePredicate->CheckNode(node) )
       {
         bool isMask = false;
         node->GetPropertyValue("binary", isMask);
         isMask |= isLabelSet->CheckNode(node);
 
         if( !isMask )
         {
           if(this->m_SelectedImage == nullptr)
           {
             this->m_SelectedImage = static_cast<mitk::Image*>(node->GetData());
             this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
           }
         }
       }
     }
   }
 
   unsigned int timeStep = renderPart->GetTimeNavigationController()->GetTime()->GetPos();
 
   if ( m_SelectedImage != nullptr && m_SelectedImage->IsInitialized())
   {
     // Check if a the selected image is a multi-channel image. If yes, statistics
     // cannot be calculated currently.
     if ( m_SelectedImage->GetPixelType().GetNumberOfComponents() > 1 )
     {
       m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Multi-component images not supported.</font>" );
       m_Controls->m_ErrorMessageLabel->show();
 
       this->InvalidateStatisticsTableView();
       m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
       m_CurrentStatisticsValid = false;
       this->m_StatisticsUpdatePending = false;
       this->DisableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
       return;
     }
 
     std::stringstream maskLabel;
     maskLabel << maskName;
     if ( maskDimension > 0 )
     {
       maskLabel << "  [" << maskDimension << "D " << maskType << "]";
     }
     m_Controls->m_SelectedMaskLabel->setText( maskLabel.str().c_str() );
     m_Controls->m_SelectedFeatureImageLabel->setText(featureImageName.c_str());
 
     // check time step validity
     if(m_SelectedImage->GetDimension() <= 3 && timeStep > m_SelectedImage->GetDimension(3)-1)
     {
       timeStep = m_SelectedImage->GetDimension(3)-1;
     }
 
     // Add the used mask time step to the mask label so the user knows which mask time step was used
     // if the image time step is bigger than the total number of mask time steps (see
     // ImageStatisticsCalculator::ExtractImageAndMask)
     if (m_SelectedImageMask != nullptr)
     {
       unsigned int maskTimeStep = timeStep;
 
       if (maskTimeStep >= m_SelectedImageMask->GetTimeSteps())
       {
         maskTimeStep = m_SelectedImageMask->GetTimeSteps() - 1;
       }
 
       m_Controls->m_SelectedMaskLabel->setText(m_Controls->m_SelectedMaskLabel->text() +
           QString(" (t=") +
           QString::number(maskTimeStep) +
           QString(")"));
     }
 
     // check if the segmentation mask is empty
     if (m_SelectedImageMask != NULL)
     {
       typedef itk::Image<unsigned char, 3> ItkImageType;
       typedef itk::ImageRegionConstIteratorWithIndex< ItkImageType > IteratorType;
 
       ItkImageType::Pointer itkImage;
 
       mitk::CastToItkImage( m_SelectedImageMask, itkImage );
 
       bool empty = true;
       IteratorType it( itkImage, itkImage->GetLargestPossibleRegion() );
       while ( !it.IsAtEnd() )
       {
         ItkImageType::ValueType val = it.Get();
         if ( val != 0 )
         {
           empty = false;
           break;
         }
         ++it;
       }
 
       if ( empty )
       {
         m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Empty segmentation mask selected...</font>" );
         m_Controls->m_ErrorMessageLabel->show();
 
         return;
       }
     }
 
     //// initialize thread and trigger it
     this->m_CalculationThread->SetIgnoreZeroValueVoxel( m_Controls->m_IgnoreZerosCheckbox->isChecked() );
     this->m_CalculationThread->Initialize( m_SelectedImage, m_SelectedImageMask, m_SelectedPlanarFigure );
     this->m_CalculationThread->SetTimeStep( timeStep );
 
     m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Calculating statistics...</font>");
     m_Controls->m_ErrorMessageLabel->show();
 
     try
     {
       // Compute statistics
       this->m_CalculationThread->start();
     }
     catch ( const mitk::Exception& e)
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.GetDescription()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::runtime_error &e )
     {
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::exception &e )
     {
       MITK_ERROR << "Caught exception: " << e.what();
 
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
   }
   else
   {
     this->m_StatisticsUpdatePending = false;
   }
 }
 
 void QmitkImageStatisticsView::SelectedDataModified()
 {
   if( !m_StatisticsUpdatePending )
   {
     emit StatisticsUpdate();
   }
 }
 
 void QmitkImageStatisticsView::NodeRemoved(const mitk::DataNode *node)
 {
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if (node->GetData() == m_SelectedImage)
   {
     m_SelectedImage = nullptr;
   }
 }
 
 void QmitkImageStatisticsView::RequestStatisticsUpdate()
 {
   if ( !m_StatisticsUpdatePending )
   {
     if(this->m_DataNodeSelectionChanged)
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->m_StatisticsUpdatePending = true;
       this->UpdateStatistics();
     }
   }
   if (this->GetRenderWindowPart())
     this->GetRenderWindowPart()->RequestUpdate();
 }
 
 void QmitkImageStatisticsView::OnHistogramNBinsCheckBoxValueChanged()
 {
     if (static_cast<unsigned int>(m_Controls->m_HistogramNBinsSpinbox->value()) != m_HistogramNBins)
     {
       m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
         this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
         this->UpdateStatistics();
     }
 }
 
 void QmitkImageStatisticsView::WriteStatisticsToGUI()
 {
   m_Controls->m_JSHistogram->Clear();
   m_IntensityProfileList.clear();
   //Disconnect OnLineRadioButtonSelected() to prevent reloading chart when radiobutton is checked programmatically
   disconnect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), 0, 0);
   connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   m_Controls->m_InfoLabel->setText("");
 
   if (m_DataNodeSelectionChanged)
   {
     this->m_StatisticsUpdatePending = false;
     this->RequestStatisticsUpdate();
     return;    // stop visualization of results and calculate statistics of new selection
   }
 
   if (this->m_CalculationThread->GetStatisticsUpdateSuccessFlag())
   {
     if (this->m_CalculationThread->GetStatisticsChangedFlag())
     {
       // Do not show any error messages
       m_Controls->m_ErrorMessageLabel->hide();
       m_CurrentStatisticsValid = true;
     }
 
     if (m_SelectedImage != nullptr) {
       //all statistics are now computed also on planar figures (lines, paths...)!
     // If a (non-closed) PlanarFigure is selected, display a line profile widget
       if (m_SelectedPlanarFigure != nullptr) {
         // Check if the (closed) planar figure is out of bounds and so no image mask could be calculated--> Intensity Profile can not be calculated
         bool outOfBounds = false;
         if (m_SelectedPlanarFigure->IsClosed() && m_SelectedImageMask == nullptr)
         {
           outOfBounds = true;
           const QString message("<font color='red'>Planar figure is on a rotated image plane or outside the image bounds.</font>");
           m_Controls->m_InfoLabel->setText(message);
         }
 
         // check whether PlanarFigure is initialized
         const mitk::PlaneGeometry *planarFigurePlaneGeometry = m_SelectedPlanarFigure->GetPlaneGeometry();
 
         if (!(planarFigurePlaneGeometry == nullptr || outOfBounds))
         {
           unsigned int timeStep = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
           mitk::Image::Pointer image;
 
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4)
           {
             mitk::ImageTimeSelector::Pointer timeSelector = mitk::ImageTimeSelector::New();
             timeSelector->SetInput(this->m_CalculationThread->GetStatisticsImage());
             timeSelector->SetTimeNr(timeStep);
             timeSelector->Update();
 
             image = timeSelector->GetOutput();
           }
           else
           {
             image = this->m_CalculationThread->GetStatisticsImage();
           }
 
           mitk::IntensityProfile::ConstPointer intensityProfile = (mitk::IntensityProfile::ConstPointer)mitk::ComputeIntensityProfile(image, m_SelectedPlanarFigure);
 
           m_IntensityProfileList = ConvertIntensityProfileToVector(intensityProfile);
           auto lineDataLabel = "Intensity profile " + m_Controls->m_SelectedMaskLabel->text().toStdString();
           m_Controls->m_JSHistogram->SetChartType(lineDataLabel, QmitkChartWidget::ChartType::line);
           m_Controls->m_JSHistogram->AddData1D(m_IntensityProfileList, lineDataLabel);
           m_Controls->m_JSHistogram->SetXAxisLabel("Distance");
           m_Controls->m_JSHistogram->SetYAxisLabel("Intensity");
           m_Controls->m_JSHistogram->Show(m_Controls->m_ShowSubchartCheckBox->isChecked());
 
           m_Controls->m_lineRadioButton->setChecked(true);
           m_Controls->m_lineRadioButton->setEnabled(false);
           m_Controls->m_barRadioButton->setEnabled(false);
           m_Controls->m_HistogramNBinsSpinbox->setEnabled(false);
           m_Controls->m_BinSizeFrame->setEnabled(false);
           m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(false);
 
           //Reconnect OnLineRadioButtonSelected()
           connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnLineRadioButtonSelected()));
           auto statisticsVector = this->m_CalculationThread->GetStatisticsData();
           //only one entry (current timestep)
           this->FillLinearProfileStatisticsTableView(statisticsVector.front().GetPointer(), this->m_CalculationThread->GetStatisticsImage());
 
           QString message("<font color='red'>Only linegraph available for an intensity profile!");
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4) {
             message += "Only current timestep displayed!";
           }
           message += "</font>";
           m_Controls->m_InfoLabel->setText(message);
           m_CurrentStatisticsValid = true;
         }
         else
         {
           // Clear statistics, histogram, and GUI
           this->InvalidateStatisticsTableView();
           m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
           m_CurrentStatisticsValid = false;
           m_Controls->m_ErrorMessageLabel->hide();
           m_Controls->m_SelectedMaskLabel->setText("None");
           this->m_StatisticsUpdatePending = false;
           if (!outOfBounds)
             m_Controls->m_InfoLabel->setText("");
           return;
         }
       }
       else
       {
         m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
 
         auto histogram = this->m_CalculationThread->GetTimeStepHistogram(this->m_CalculationThread->GetTimeStep()).GetPointer();
 
         auto imageLabelName = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageLabelName);
         m_Controls->m_JSHistogram->SetChartType(imageLabelName, QmitkChartWidget::ChartType::bar);
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Gray value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(true);
         m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
         this->FillStatisticsTableView(this->m_CalculationThread->GetStatisticsData(), this->m_CalculationThread->GetStatisticsImage());
       }
       m_CurrentStatisticsValid = true;
     }
   }
   else
   {
     m_Controls->m_SelectedMaskLabel->setText("None");
     m_Controls->m_ErrorMessageLabel->setText(m_CalculationThread->GetLastErrorMessage().c_str());
     m_Controls->m_ErrorMessageLabel->show();
 
     // Clear statistics and histogram
     this->InvalidateStatisticsTableView();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_CurrentStatisticsValid = false;
 
   }
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   this->m_StatisticsUpdatePending = false;
 }
 
 void QmitkImageStatisticsView::FillStatisticsTableView(
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics,
     const mitk::Image *image )
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(image->GetTimeSteps());
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(image->GetTimeSteps() > 1);
 
   // Set Checkbox for complete copy of statistic table
   if(image->GetTimeSteps()>1)
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(true);
   }
   else
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(false);
     this->m_Controls->m_CheckBox4dCompleteTable->setChecked(false);
   }
 
 
   for (unsigned int t = 0; t < image->GetTimeSteps(); t++)
   {
     this->m_Controls->m_StatisticsTable->setHorizontalHeaderItem(t,
         new QTableWidgetItem(QString::number(t)));
 
     if (statistics.at(t)->GetMaxIndex().size()==3)
     {
       mitk::Point3D index, max, min;
       index[0] = statistics.at(t)->GetMaxIndex()[0];
       index[1] = statistics.at(t)->GetMaxIndex()[1];
       index[2] = statistics.at(t)->GetMaxIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, max);
       this->m_WorldMaxList.push_back(max);
       index[0] = statistics.at(t)->GetMinIndex()[0];
       index[1] = statistics.at(t)->GetMinIndex()[1];
       index[2] = statistics.at(t)->GetMinIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, min);
       this->m_WorldMinList.push_back(min);
     }
 
     auto statisticsVector = AssembleStatisticsIntoVector(statistics.at(t).GetPointer(), image);
 
     unsigned int count = 0;
     for (const auto& entry : statisticsVector) {
       auto item = new QTableWidgetItem(entry);
       this->m_Controls->m_StatisticsTable->setItem(count, t, item);
       count++;
     }
 
     }
 
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 
   // make sure the current timestep's column is highlighted (and the correct histogram is displayed)
   unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
       GetPos();
   mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(),
       t);
   this->OnTimeChanged(timeEvent);
 
   t = std::min(image->GetTimeSteps() - 1, t);
 
   // See bug 18340
   /*QString hotspotMean; hotspotMean.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMean(), 0, 'f', decimals));
   hotspotMean += " (";
   for (int i=0; i<s[t].GetHotspotIndex().size(); i++)
   {
   hotspotMean += QString::number(s[t].GetHotspotIndex()[i]);
   if (i<s[t].GetHotspotIndex().size()-1)
   hotspotMean += ",";
   }
   hotspotMean += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 7, t, new QTableWidgetItem( hotspotMean ) );
 
   QString hotspotMax; hotspotMax.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMax(), 0, 'f', decimals));
   hotspotMax += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMaxIndex().size(); i++)
   {
   hotspotMax += QString::number(s[t].GetHotspotStatistics().GetMaxIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMaxIndex().size()-1)
   hotspotMax += ",";
   }
   hotspotMax += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 8, t, new QTableWidgetItem( hotspotMax ) );
 
   QString hotspotMin; hotspotMin.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMin(), 0, 'f', decimals));
   hotspotMin += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMinIndex().size(); i++)
   {
   hotspotMin += QString::number(s[t].GetHotspotStatistics().GetMinIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMinIndex().size()-1)
   hotspotMin += ",";
   }
   hotspotMin += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 9, t, new QTableWidgetItem( hotspotMin ) );*/
 }
 
 std::vector<QString> QmitkImageStatisticsView::AssembleStatisticsIntoVector(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics, mitk::Image::ConstPointer image, bool noVolumeDefined) const
 {
   std::vector<QString> result;
 
   unsigned int decimals = 2;
 
   //statistics of higher order should have 5 decimal places because they used to be very small
   unsigned int decimalsHigherOrderStatistics = 5;
 
   if (image->GetPixelType().GetComponentType() == itk::ImageIOBase::DOUBLE || image->GetPixelType().GetComponentType() == itk::ImageIOBase::FLOAT)
   {
     decimals = 5;
   }
 
   result.push_back(GetFormattedString(statistics->GetMean(), decimals));
   result.push_back(GetFormattedString(statistics->GetMedian(), decimals));
   result.push_back(GetFormattedString(statistics->GetStd(), decimals));
   result.push_back(GetFormattedString(statistics->GetRMS(), decimals));
   result.push_back(GetFormattedString(statistics->GetMax(), decimals) + " " + GetFormattedIndex(statistics->GetMaxIndex()));
   result.push_back(GetFormattedString(statistics->GetMin(), decimals) + " " + GetFormattedIndex(statistics->GetMinIndex()));
   //to prevent large negative values of empty image statistics
   if (statistics->GetN() != std::numeric_limits<long>::min()) {
     result.push_back(GetFormattedString(statistics->GetN(), 0));
 
     const mitk::BaseGeometry *geometry = image->GetGeometry();
     if (geometry != NULL && !noVolumeDefined)
   {
       const mitk::Vector3D &spacing = image->GetGeometry()->GetSpacing();
       double volume = spacing[0] * spacing[1] * spacing[2] * static_cast<double>(statistics->GetN());
       result.push_back(GetFormattedString(volume, decimals));
   }
     else {
       result.push_back("NA");
   }
   }
   else {
     result.push_back("NA");
     result.push_back("NA");
   }
 
   result.push_back(GetFormattedString(statistics->GetSkewness(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetKurtosis(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetUniformity(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetEntropy(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetMPP(), decimals));
   result.push_back(GetFormattedString(statistics->GetUPP(), decimalsHigherOrderStatistics));
 
   return result;
 }
 
 void QmitkImageStatisticsView::FillLinearProfileStatisticsTableView(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics,
   const mitk::Image *image)
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
 
   m_PlanarFigureStatistics = this->AssembleStatisticsIntoVector(statistics, image, true);
 
   for (unsigned int i = 0; i< m_PlanarFigureStatistics.size(); i++)
   {
     this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem(m_PlanarFigureStatistics[i] ));
   }
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 }
 
 void QmitkImageStatisticsView::InvalidateStatisticsTableView()
 {
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
 
   for ( int i = 0; i < this->m_Controls->m_StatisticsTable->rowCount(); ++i )
   {
     {
       this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem( "NA" ) );
     }
   }
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(STAT_TABLE_BASE_HEIGHT);
 }
 
 void QmitkImageStatisticsView::Activated()
 {
 }
 
 void QmitkImageStatisticsView::Deactivated()
 {
 }
 
 void QmitkImageStatisticsView::Visible()
 {
   m_Visible = true;
 
   mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
   if (renderWindow)
   {
     itk::ReceptorMemberCommand<QmitkImageStatisticsView>::Pointer cmdTimeEvent =
         itk::ReceptorMemberCommand<QmitkImageStatisticsView>::New();
     cmdTimeEvent->SetCallbackFunction(this, &QmitkImageStatisticsView::OnTimeChanged);
 
     // It is sufficient to add the observer to the axial render window since the GeometryTimeEvent
     // is always triggered by all views.
     m_TimeObserverTag = renderWindow->GetQmitkRenderWindow("axial")->
         GetSliceNavigationController()->
         AddObserver(mitk::SliceNavigationController::GeometryTimeEvent(nullptr, 0), cmdTimeEvent);
   }
 
   if (m_DataNodeSelectionChanged)
   {
     if (this->IsCurrentSelectionValid())
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->SelectionChanged(this->GetDataManagerSelection());
     }
     m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::Hidden()
 {
   m_Visible = false;
 
   // The slice navigation controller observer is removed here instead of in the destructor.
   // If it was called in the destructor, the application would freeze because the view's
   // destructor gets called after the render windows have been destructed.
   if ( m_TimeObserverTag != 0 )
   {
     mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
     if (renderWindow)
     {
       renderWindow->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->
           RemoveObserver( m_TimeObserverTag );
     }
     m_TimeObserverTag = 0;
   }
 }
 
 void QmitkImageStatisticsView::SetFocus()
 {
 }
 
 std::map<double, double> QmitkImageStatisticsView::ConvertHistogramToMap(itk::Statistics::Histogram<double>::ConstPointer histogram) const
 {
   std::map<double, double> histogramMap;
 
-	auto endIt = histogram->End();
-	auto it = histogram->Begin();
+  auto endIt = histogram->End();
+  auto it = histogram->Begin();
 
-	// generating Lists of measurement and frequencies
+  // generating Lists of measurement and frequencies
   for (; it != endIt; ++it)
-	{
+  {
     double frequency = it.GetFrequency();
     double measurement = it.GetMeasurementVector()[0];
     histogramMap.emplace(measurement, frequency);
-	}
+  }
 
-	return histogramMap;
+  return histogramMap;
 }
 
 std::vector<double> QmitkImageStatisticsView::ConvertIntensityProfileToVector(mitk::IntensityProfile::ConstPointer intensityProfile) const
 {
   std::vector<double> intensityProfileList;
   auto end = intensityProfile->End();
 
-	for (auto it = intensityProfile->Begin(); it != end; ++it)
-	{
+  for (auto it = intensityProfile->Begin(); it != end; ++it)
+  {
     intensityProfileList.push_back(it.GetMeasurementVector()[0]);
-	}
-	return intensityProfileList;
+  }
+  return intensityProfileList;
 }
 
 QString QmitkImageStatisticsView::GetFormattedString(double value, unsigned int decimals) const
 {
   typedef mitk::ImageStatisticsCalculator::StatisticsContainer::RealType RealType;
   RealType maxVal = std::numeric_limits<RealType>::max();
 
   if (value == maxVal)
   {
     return QString("NA");
   }
   else
   {
     return QString("%1").arg(value, 0, 'f', decimals);
   }
 }
 
 QString QmitkImageStatisticsView::GetFormattedIndex(const vnl_vector<int>& vector) const
 {
   if (vector.empty()) {
     return QString();
   }
   QString formattedIndex("(");
   for (const auto& entry : vector)
   {
     formattedIndex += QString::number(entry);
     formattedIndex += ",";
   }
   formattedIndex.chop(1);
   formattedIndex += ")";
   return formattedIndex;
 }