diff --git a/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/Manual.dox b/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/Manual.dox index 18d01959e0..5e2afbb7fa 100644 --- a/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/Manual.dox +++ b/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/Manual.dox @@ -1,20 +1,32 @@ /** \page org_mitk_gui_qt_pharmacokinetics_concentration_mri The Concentration Curve Converter View \imageMacro{pharmacokinetics_concentration_doc.svg,"Icon of the Concentration Curve Converter View",3.0} \tableofcontents \section org_mitk_gui_qt_pharmacokinetics_concentration_mri_overview Overview -This view offers a dedicated stand-alone conversion of MR image signal intensities to contrast agent concentration. -It contains a selection of the conversion tools for T1-weighted signal intensities, which are a part of the DCE MR Perfusion Datafit View (see \ref FIT_DCE_Settings_concentration). -Additionally, it allows for conversion between T2-weighted signal intensities and contrast agent concentration. +This view offers a dedicated tool for the conversion of MR image signal intensities to contrast agent (CA) concentration. +It contains a subset of the conversion tools for T1-weighted signal intensities, which are a part of the DCE MR Perfusion Datafit View (see \ref FIT_DCE_Settings_concentration). +Additionally, it allows for conversion between T2-weighted MR signal intensities and contrast agent concentration. \section org_mitk_gui_qt_pharmacokinetics_concentration_mri_Contact Contact information This plug-in is being developed by the SIDT group (Software Development for Integrated Diagnostics and Therapy) at the German Cancer Research Center (DKFZ). If you have any questions, need support, find a bug or have a feature request, feel free to contact us at www.mitk.org. +\section org_mitk_gui_qt_pharmacokinetics_concentration_mri_T1_conversion Conversion of T1-weighted MRI data +\imageMacro{concentration_curve_converter_T1_weighted4D.png,"Example screenshot of the conversion of T1-weighted MR images",3.0} +The view offers the options to chose between a 3D Image and a 4D image. If a 4D image is selected, the Selected Time Series needs to be selected from the Data Manager. +In this case, the baseline image is automatically extracted as the first time point image of the time series. +In case of a 3D image to be converted, additionally to the selected 3D image a Baseline Image (without CA) has to be specified.\n\n +In the configuration section, the following types of conversion can be chosen: +- Absolute Signal Enhancement: The contrast agent concentration c is calculated according to the formula: c = k*S(t)-S(0), where S(t) is the dynamic signal intensity, S(0) the baseline signal and k a user-defined conversion factor. +- Relative Signal Enhancement: The contrast agent concentration c is calculated according to the formula: c = k*(S(t)-S(0))/S(0), where S(t) is the dynamic signal intensity, S(0) the baseline signal and k a user-defined conversion factor. +- Turbo Flash Sequence: The conversion from signal S(t) to contrast agent concentration c is calculated according to the turbo FLASH sequence specific formula: + + +\section org_mitk_gui_qt_pharmacokinetics_concentration_mri_T2_conversion Conversion of T2-weighted MRI data */ diff --git a/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/concentration_curve_converter_T1_weighted4D.png b/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/concentration_curve_converter_T1_weighted4D.png new file mode 100644 index 0000000000..ef521cc592 Binary files /dev/null and b/Plugins/org.mitk.gui.qt.pharmacokinetics.concentration.mri/documentation/UserManual/concentration_curve_converter_T1_weighted4D.png differ