diff --git a/Plugins/org.mitk.gui.qt.diffusionimaging/src/internal/QmitkTbssSkeletonizationView.cpp b/Plugins/org.mitk.gui.qt.diffusionimaging/src/internal/QmitkTbssSkeletonizationView.cpp index 1f305855cd..cf3bc30d4c 100644 --- a/Plugins/org.mitk.gui.qt.diffusionimaging/src/internal/QmitkTbssSkeletonizationView.cpp +++ b/Plugins/org.mitk.gui.qt.diffusionimaging/src/internal/QmitkTbssSkeletonizationView.cpp @@ -1,442 +1,442 @@ /*=================================================================== The Medical Imaging Interaction Toolkit (MITK) Copyright (c) German Cancer Research Center, Division of Medical and Biological Informatics. All rights reserved. This software is distributed WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See LICENSE.txt or http://www.mitk.org for details. ===================================================================*/ // Qmitk #include "QmitkTbssSkeletonizationView.h" #include #include #include #include #include // mitk #include // Qt #include #include //vtk #include #include // Boost #include const std::string QmitkTbssSkeletonizationView::VIEW_ID = "org.mitk.views.tbssskeletonization"; using namespace berry; QmitkTbssSkeletonizationView::QmitkTbssSkeletonizationView() : QmitkFunctionality() , m_Controls( 0 ) , m_MultiWidget( NULL ) { } QmitkTbssSkeletonizationView::~QmitkTbssSkeletonizationView() { } void QmitkTbssSkeletonizationView::OnSelectionChanged(std::vector nodes) { //datamanager selection changed if (!this->IsActivated()) return; bool found3dImage = false; bool found4dImage = false; // iterate selection for ( int i=0; iGetData(); if(nodeData) { if(QString("Image").compare(nodeData->GetNameOfClass())==0) { mitk::Image* img = static_cast(nodeData); if(img->GetDimension() == 3) { found3dImage = true; } else if(img->GetDimension() == 4) { found4dImage = true; } } } } this->m_Controls->m_Skeletonize->setEnabled(found3dImage); this->m_Controls->m_Project->setEnabled(found3dImage && found4dImage); this->m_Controls->m_OutputMask->setEnabled(found3dImage && found4dImage); this->m_Controls->m_OutputDistanceMap->setEnabled(found3dImage && found4dImage); } void QmitkTbssSkeletonizationView::CreateQtPartControl( QWidget *parent ) { // build up qt view, unless already done if ( !m_Controls ) { // create GUI widgets from the Qt Designer's .ui file m_Controls = new Ui::QmitkTbssSkeletonizationViewControls; m_Controls->setupUi( parent ); this->CreateConnections(); } } void QmitkTbssSkeletonizationView::Activated() { QmitkFunctionality::Activated(); } void QmitkTbssSkeletonizationView::Deactivated() { QmitkFunctionality::Deactivated(); } void QmitkTbssSkeletonizationView::CreateConnections() { if ( m_Controls ) { connect( (QObject*)(m_Controls->m_Skeletonize), SIGNAL(clicked()), this, SLOT(Skeletonize() )); connect( (QObject*)(m_Controls->m_Project), SIGNAL(clicked()), this, SLOT(Project() )); } } void QmitkTbssSkeletonizationView::StdMultiWidgetAvailable (QmitkStdMultiWidget &stdMultiWidget) { m_MultiWidget = &stdMultiWidget; } void QmitkTbssSkeletonizationView::StdMultiWidgetNotAvailable() { m_MultiWidget = NULL; } void QmitkTbssSkeletonizationView::Skeletonize() { typedef itk::SkeletonizationFilter SkeletonisationFilterType; SkeletonisationFilterType::Pointer skeletonizer = SkeletonisationFilterType::New(); std::vector nodes = this->GetDataManagerSelection(); mitk::Image::Pointer meanImage = mitk::Image::New(); std::string name = ""; for ( int i=0; iGetData(); if(nodeData) { if(QString("Image").compare(nodeData->GetNameOfClass())==0) { mitk::Image* img = static_cast(nodeData); if(img->GetDimension() == 3) { meanImage = img; name = nodes[i]->GetName(); } } } } // Calculate skeleton FloatImageType::Pointer itkImg = FloatImageType::New(); mitk::CastToItkImage(meanImage, itkImg); skeletonizer->SetInput(itkImg); skeletonizer->Update(); FloatImageType::Pointer output = skeletonizer->GetOutput(); mitk::Image::Pointer mitkOutput = mitk::Image::New(); mitk::CastToMitkImage(output, mitkOutput); name += "_skeleton"; AddToDataStorage(mitkOutput, name); } void QmitkTbssSkeletonizationView::Project() { typedef itk::SkeletonizationFilter SkeletonisationFilterType; typedef itk::ProjectionFilter ProjectionFilterType; typedef itk::DistanceMapFilter DistanceMapFilterType; SkeletonisationFilterType::Pointer skeletonizer = SkeletonisationFilterType::New(); std::vector nodes = this->GetDataManagerSelection(); mitk::Image::Pointer meanImage = mitk::Image::New(); mitk::Image::Pointer subjects = mitk::Image::New(); for ( int i=0; iGetData(); if(nodeData) { if(QString("Image").compare(nodeData->GetNameOfClass())==0) { mitk::Image* img = static_cast(nodeData); if(img->GetDimension() == 3) { meanImage = img; } else if(img->GetDimension() == 4) { subjects = img; } } } } Float4DImageType::Pointer allFA = ConvertToItk(subjects); // Calculate skeleton FloatImageType::Pointer itkImg = FloatImageType::New(); mitk::CastToItkImage(meanImage, itkImg); skeletonizer->SetInput(itkImg); skeletonizer->Update(); FloatImageType::Pointer output = skeletonizer->GetOutput(); mitk::Image::Pointer mitkOutput = mitk::Image::New(); mitk::CastToMitkImage(output, mitkOutput); AddToDataStorage(mitkOutput, "mean_FA_skeletonised"); // Retrieve direction image needed later by the projection filter DirectionImageType::Pointer directionImg = skeletonizer->GetVectorImage(); // Calculate distance image DistanceMapFilterType::Pointer distanceMapFilter = DistanceMapFilterType::New(); distanceMapFilter->SetInput(output); distanceMapFilter->Update(); FloatImageType::Pointer distanceMap = distanceMapFilter->GetOutput(); if(m_Controls->m_OutputDistanceMap->isChecked()) { mitk::Image::Pointer mitkDistance = mitk::Image::New(); mitk::CastToMitkImage(distanceMap, mitkDistance); AddToDataStorage(mitkDistance, "distance map"); } // Do projection // Ask a threshold to create a skeleton mask double threshold = -1.0; while(threshold == -1.0) { threshold = QInputDialog::getDouble(m_Controls->m_Skeletonize, tr("Specify the FA threshold"), tr("Threshold:"), QLineEdit::Normal, 0.2); if(threshold < 0.0 || threshold > 1.0) { QMessageBox msgBox; msgBox.setText("Please choose a value between 0 and 1"); msgBox.exec(); threshold = -1.0; } } typedef itk::BinaryThresholdImageFilter ThresholdFilterType; ThresholdFilterType::Pointer thresholder = ThresholdFilterType::New(); thresholder->SetInput(output); thresholder->SetLowerThreshold(threshold); thresholder->SetUpperThreshold(std::numeric_limits::max()); thresholder->SetOutsideValue(0); thresholder->SetInsideValue(1); thresholder->Update(); CharImageType::Pointer thresholdedImg = thresholder->GetOutput(); if(m_Controls->m_OutputMask->isChecked()) { mitk::Image::Pointer mitkThresholded = mitk::Image::New(); mitk::CastToMitkImage(thresholdedImg, mitkThresholded); std::string maskName = "skeleton_mask_at_" + boost::lexical_cast(threshold); AddToDataStorage(mitkThresholded, maskName); } typedef itk::ImageFileReader< CharImageType > CharReaderType; CharReaderType::Pointer reader = CharReaderType::New(); reader->SetFileName("/local/testing/LowerCingulum_1mm.nii.gz"); reader->Update(); CharImageType::Pointer cingulum = reader->GetOutput(); ProjectionFilterType::Pointer projectionFilter = ProjectionFilterType::New(); projectionFilter->SetDistanceMap(distanceMap); projectionFilter->SetDirections(directionImg); projectionFilter->SetAllFA(allFA); projectionFilter->SetTube(cingulum); projectionFilter->SetSkeleton(thresholdedImg); projectionFilter->Project(); Float4DImageType::Pointer projected = projectionFilter->GetProjections(); mitk::Image::Pointer mitkProjections = mitk::Image::New(); mitk::CastToMitkImage(projected, mitkProjections); AddToDataStorage(mitkProjections, "all_FA_projected"); } void QmitkTbssSkeletonizationView::AddToDataStorage(mitk::Image* img, std::string name) { mitk::DataNode::Pointer result = mitk::DataNode::New(); result->SetProperty( "name", mitk::StringProperty::New(name) ); result->SetData( img ); // add new image to data storage and set as active to ease further processing GetDefaultDataStorage()->Add( result ); } Float4DImageType::Pointer QmitkTbssSkeletonizationView::ConvertToItk(mitk::Image::Pointer image) { Float4DImageType::Pointer output = Float4DImageType::New(); mitk::Geometry3D* geo = image->GetGeometry(); mitk::Vector3D mitkSpacing = geo->GetSpacing(); mitk::Point3D mitkOrigin = geo->GetOrigin(); Float4DImageType::SpacingType spacing; spacing[0] = mitkSpacing[0]; spacing[1] = mitkSpacing[1]; spacing[2] = mitkSpacing[2]; spacing[3] = 1.0; // todo: check if spacing has length 4 Float4DImageType::PointType origin; origin[0] = mitkOrigin[0]; origin[1] = mitkOrigin[1]; origin[2] = mitkOrigin[2]; origin[3] = 0; Float4DImageType::SizeType size; size[0] = image->GetDimension(0); size[1] = image->GetDimension(1); size[2] = image->GetDimension(2); size[3] = image->GetDimension(3); Float4DImageType::DirectionType dir; vtkLinearTransform* lin = geo->GetVtkTransform(); vtkMatrix4x4 *m = lin->GetMatrix(); dir.Fill(0.0); for(int x=0; x<3; x++) { for(int y=0; y<3; y++) { dir[x][y] = m->GetElement(x,y); } } dir[3][3] = 1; output->SetSpacing(spacing); output->SetOrigin(origin); output->SetRegions(size); output->SetDirection(dir); output->Allocate(); if(image->GetDimension() == 4) { int timesteps = image->GetDimension(3); try{ // REPLACE THIS METHODE()ConvertToItk) WITH mitk::CastToItk - mitk::ImagePixelReadAccessor imageAccessor(image); + mitk::ImagePixelReadAccessor imageAccessor(image, image->GetSliceData()); // iterate through the subjects and copy data to output for(int t=0; tGetDimension(0); x++) { for(int y=0; yGetDimension(1); y++) { for(int z=0; zGetDimension(2); z++) { itk::Index<4> ix4; ix4[0] = x; ix4[1] = y; ix4[2] = z; ix4[3] = t; output->SetPixel(ix4, imageAccessor.GetPixelByIndex(ix4)); } } } } }catch(std::exception & e) { MITK_INFO << e.what(); } } return output; }