diff --git a/CMake/BuildConfigurations/mitkNavigationModules.cmake b/CMake/BuildConfigurations/mitkNavigationModules.cmake
new file mode 100644
index 0000000000..33a1e44067
--- /dev/null
+++ b/CMake/BuildConfigurations/mitkNavigationModules.cmake
@@ -0,0 +1,37 @@
+message(STATUS "Configuring MITK Navigation Modules Build")
+
+set(MITK_CONFIG_PACKAGES
+  ACVD
+  QT
+  BLUEBERRY
+)
+
+# Enable open cv and open igt link, which is a necessary configuration
+set(MITK_USE_OpenCV ON CACHE BOOL "MITK Use OpenCV Library" FORCE)
+set(MITK_USE_OpenIGTLink ON CACHE BOOL "MITK Use OpenIGTLink Library" FORCE)
+
+# Enable default plugins and the navigation modules
+set(MITK_CONFIG_PLUGINS
+  org.mitk.gui.qt.datamanager
+  org.mitk.gui.qt.stdmultiwidgeteditor
+  org.mitk.gui.qt.dicom
+  org.mitk.gui.qt.imagenavigator
+  org.mitk.gui.qt.measurementtoolbox
+  org.mitk.gui.qt.properties
+  org.mitk.gui.qt.segmentation
+  org.mitk.gui.qt.volumevisualization
+  org.mitk.planarfigure
+  org.mitk.gui.qt.moviemaker
+  org.mitk.gui.qt.pointsetinteraction
+  org.mitk.gui.qt.registration
+  org.mitk.gui.qt.remeshing
+  org.mitk.gui.qt.viewnavigator
+  org.mitk.gui.qt.imagecropper
+  org.mitk.gui.qt.igtexamples
+  org.mitk.gui.qt.igttracking
+  org.mitk.gui.qt.igtlplugin
+  org.mitk.gui.qt.ultrasound
+  org.mitk.gui.qt.toftutorial
+  org.mitk.gui.qt.tofutil
+)
+