diff --git a/CMake/mitkBuildConfigurationWorkbenchRelease.cmake b/CMake/mitkBuildConfigurationWorkbenchRelease.cmake
index d354b0bb40..fc664bfeb3 100644
--- a/CMake/mitkBuildConfigurationWorkbenchRelease.cmake
+++ b/CMake/mitkBuildConfigurationWorkbenchRelease.cmake
@@ -1,3 +1,11 @@
 include(${CMAKE_CURRENT_LIST_DIR}/mitkBuildConfigurationDefault.cmake)
 
 set(MITK_VTK_DEBUG_LEAKS OFF CACHE BOOL "Enable VTK Debug Leaks" FORCE)
+
+# Ensure that the in-application help can be build
+if(NOT DOXYGEN_EXECUTABLE)
+  message(FATAL_ERROR "DOXYGEN_EXECUTABLE is not set")
+endif()
+if(NOT BLUEBERRY_USE_QT_HELP)
+  message(FATAL_ERROR "BLUEBERRY_USE_QT_HELP is required to be set to ON")
+endif()