diff --git a/Documentation/Doxygen/2-UserManual/MITKPluginManualsList.dox b/Documentation/Doxygen/2-UserManual/MITKPluginManualsList.dox index b567c4c83e..79781232cc 100644 --- a/Documentation/Doxygen/2-UserManual/MITKPluginManualsList.dox +++ b/Documentation/Doxygen/2-UserManual/MITKPluginManualsList.dox @@ -1,84 +1,84 @@ /** \page PluginListPage MITK Plugin Manuals The plugins and bundles provide much of the extended functionality of MITK. Each encapsulates a solution to a problem and associated features. This way one can easily assemble the necessary capabilites for a workflow without adding a lot of bloat, by combining plugins as needed. \subpage PluginListGeneralPage \subpage PluginListSpecificPage */ diff --git a/Documentation/Doxygen/2-UserManual/MITKPluginSpecificManualsList.dox b/Documentation/Doxygen/2-UserManual/MITKPluginSpecificManualsList.dox index ef1ea02159..2736e969cf 100644 --- a/Documentation/Doxygen/2-UserManual/MITKPluginSpecificManualsList.dox +++ b/Documentation/Doxygen/2-UserManual/MITKPluginSpecificManualsList.dox @@ -1,45 +1,45 @@ /** \page PluginListSpecificPage List of Application-specific Plugins \li \subpage org_mitk_gui_qt_aicpregistration \li \subpage org_mitk_gui_qt_cest \li \subpage org_mitk_gui_qt_classificationsegmentation \li \subpage org_mitk_gui_qt_flowapplication \li \subpage org_mitk_views_cmdlinemodules \li \subpage org_mitk_views_pharmacokinetics_concentration_mri \li \subpage org_mitk_views_pharmacokinetics_mri \li \subpage org_mitk_gui_qt_pharmacokinetics_pet \li \subpage org_mitk_gui_qt_eventrecorder \li \subpage org_mitk_gui_qt_examples \li \subpage org_mitk_gui_qt_geometrytools \li \subpage org_mitk_gui_qt_igtexample \li \subpage org_mitk_gui_qt_igtlplugin \li \subpage org_mitk_gui_qt_igttracking \li \subpage org_mitk_gui_qt_igttrackingsemiautomaticmeasurement \li \subpage org_mitk_views_imagestatistics \li \subpage org_mitk_gui_qt_lasercontrol \li \subpage org_mitk_gui_qt_fit_demo \li \subpage org_mitk_gui_qt_fit_genericfitting \li \subpage org_mitk_gui_qt_fit_inspector \li \subpage org_mitkexamplesopencv \li \subpage org_mitk_gui_qt_overlaymanager \li \subpage org_mitk_gui_qt_mitkphenotyping \li \subpage org_mitk_gui_qt_photoacoustics_pausmotioncompensation \li \subpage org_mitk_example_gui_pcaexample \li \subpage org_mitk_gui_qt_preprocessing_resampling - \li \subpage org_mitk_gui_qt_pharmacokinetics_curvedescriptor + \li \subpage org_mitk_views_pharmacokinetics_curvedescriptor \li \subpage org_mitk_gui_qt_photoacoustics_imageprocessing \li \subpage org_mitk_gui_qt_pharmacokinetics_simulation \li \subpage org_mitk_gui_qt_pointsetinteractionmultispectrum \li \subpage org_mitk_gui_qt_renderwindowmanager \li \subpage org_mitk_gui_qt_photoacoustics_spectralunmixing \li \subpage org_mitk_gui_qt_spectrocamrecorder \li \subpage org_surfacematerialeditor \li \subpage org_blueberry_ui_qt_objectinspector \li \subpage org_toftutorial \li \subpage org_mitk_gui_qt_ultrasound \li \subpage org_mitk_gui_qt_igt_app_echotrack \li \subpage org_mitk_gui_qt_xnat */ \ No newline at end of file diff --git a/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/Manual.dox b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/Manual.dox index d5ece877b8..1814f00b35 100644 --- a/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/Manual.dox +++ b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/Manual.dox @@ -1,26 +1,27 @@ /** -\page org_mitk_gui_qt_pharmacokinetics_curvedescriptor The Perfusion Curve Description Parameters View +\page org_mitk_views_pharmacokinetics_curvedescriptor The Perfusion Curve Description Parameters View \imageMacro{pharmacokinetics_curve_desc_doc.svg,"Icon of the Perfusion Curve Description Parameters View",3.0} \tableofcontents -\section org_mitk_gui_qt_pharmacokinetics_curvedescriptor_overview Overview -In cases where data quality is not sufficient for dedicated pharmacokinetic analysis, or if global scouting of the overall image should be performed to identify regions of interest, it is often advisable to use semi-quantitative measures that describe the general shape and type of the curve. The Perfusion Curve Description Parameters plugin can be used to voxelwise calculate these parameters. -Currently the following parameters are offered by the tool: -- area-under-the-curve (AUC) -- area-under the first moment curve (AUMC), -- mean-residence-time (MRT; AUMC/AUC) -- time to peak and maximum signal - -These parameters are calculated directly from the sampled data. -AUC and AUMC are calculated by step-wise integration with linear interpolation between sampling points. Maximum and time to peak are derived from the highest intensity value (overall maximum) of all data points. -Note: If semi-quantitative parameters should be calculated from concentration time curves rather than raw data signal intensities, use the concentration n curve converter view (See 5) -Parameters of interest can be selected from the list. Selecting a 4D image in the Data manager enables the Calculate Parameters button. Resulting parameter maps will afterwards be added to the data manager as subnodes to the analyzed 4D image. - -\section org_mitk_gui_qt_pharmacokinetics_curvedescriptor_Contact Contact information -This plug-in is being developed by Charlotte Debus and the SIDT group (Software development for Integrated Diagnostics -and Therapy) at the German Cancer Research Center (DKFZ). -If you have any questions, need support, find a bug or have a feature request, feel free to contact us at www.mitk.org. +\section org_mitk_views_pharmacokinetics_curvedescriptor_overview Overview +In cases where data quality is not sufficient for dedicated pharmacokinetic analysis, or if global scouting of the overall image is performed to identify regions of interest, it is often advisable to use semi-quantitative measures that describe the general shape and type of the curve. +The Perfusion Curve Description Parameters View can be used to voxelwise calculate these parameters. + +Currently the following parameters are offered by the tool (visualized in figure 1): +\imageMacro{pharmacokinetics_curve_desc_parameter_description.png,"Figure 1: Calculation of currently available descriptive parameters",3.0} + +- area-under-the-curve (AUC): The area under the signal time curve is calculated by step-wise integration with linear interpolation between sampling points. +- area-under the first moment curve (AUMC): The area under the first moment signal time curve is calculated by step-wise integration with linear interpolation between sampling points. +- mean-residence-time (MRT): The mean residence time is calculated as MRT = AUMC/AUC. +- time-to-peak: The duration between the onset time and the time of the maximum signal of the curve. +- maximum signal: The overall maximum of all data points of the curve. + +These parameters are usually calculated directly from the raw data signal intensities of the acquired MR image. +Alternatively, if semi-quantitative parameters should be calculated from concentration time curves, use the \ref org_mitk_views_pharmacokinetics_concentration_mri prior to the parameter calculation. +Parameters of interest can be selected from the list. Selecting a 4D image enables the Calculate Parameters button. +Resulting parameter maps will afterwards be added to the data manager as subnodes to the analyzed 4D image. + */ diff --git a/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/pharmacokinetics_curve_desc_parameter_description.png b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/pharmacokinetics_curve_desc_parameter_description.png new file mode 100644 index 0000000000..61f2919454 Binary files /dev/null and b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/documentation/UserManual/pharmacokinetics_curve_desc_parameter_description.png differ diff --git a/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/plugin.xml b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/plugin.xml index 3239639a5f..6a25813a56 100644 --- a/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/plugin.xml +++ b/Plugins/org.mitk.gui.qt.pharmacokinetics.curvedescriptor/plugin.xml @@ -1,12 +1,12 @@ -