diff --git a/Modules/Chart/CMakeLists.txt b/Modules/Chart/CMakeLists.txt
index ca2284bfa7..ef1102c255 100644
--- a/Modules/Chart/CMakeLists.txt
+++ b/Modules/Chart/CMakeLists.txt
@@ -1,9 +1,9 @@
-SET (CHART_QT_MINIMUM_VERSION 5.9.0)
-IF (Qt5WebEngineWidgets_VERSION LESS CHART_QT_MINIMUM_VERSION)
-  MESSAGE(WARNING "MitkChart module requires at least ${CHART_QT_MINIMUM_VERSION}. Install this Qt version or above if you want to use MitkChart.")
-ELSE()
-  MITK_CREATE_MODULE(
-    DEPENDS MitkCore
-    PACKAGE_DEPENDS PRIVATE Qt5|WebEngineWidgets
-  )
+SET (CHART_QT_MINIMUM_VERSION 5.10.0)
+IF (Qt5WebEngineWidgets_VERSION VERSION_LESS CHART_QT_MINIMUM_VERSION)
+  MESSAGE(AUTHOR_WARNING "MitkChart module requires at least ${CHART_QT_MINIMUM_VERSION}. Install this Qt version or above if you want to use MitkChart with full functionality.")
 ENDIF()
+
+MITK_CREATE_MODULE(
+  DEPENDS MitkCore
+  PACKAGE_DEPENDS PRIVATE Qt5|WebEngineWidgets
+)
diff --git a/Modules/Chart/src/QmitkChartWidget.cpp b/Modules/Chart/src/QmitkChartWidget.cpp
index 3b6bfc2e26..d60195802e 100644
--- a/Modules/Chart/src/QmitkChartWidget.cpp
+++ b/Modules/Chart/src/QmitkChartWidget.cpp
@@ -1,537 +1,540 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include <regex>
 
 #include <QmitkChartWidget.h>
 #include <QGridLayout>
 #include <QWebChannel>
 #include <QWebEngineView>
 
 #include <QmitkChartData.h>
 #include <QmitkChartxyData.h>
 #include "mitkExceptionMacro.h"
 
 class QmitkChartWidget::Impl final
 {
 public:
   explicit Impl(QWidget* parent);
   ~Impl();
 
   Impl(const Impl&) = delete;
   Impl& operator=(const Impl&) = delete;
 
   void AddData1D(const std::vector<double>& data1D, const std::string& label, QmitkChartWidget::ChartType chartType);
   void AddData2D(const std::map<double, double>& data2D, const std::string& label, QmitkChartWidget::ChartType chartType);
 
   void RemoveData(const std::string& label);
 
   void ClearData();
 
   void SetColor(const std::string& label, const std::string& colorName);
   void SetLineStyle(const std::string& label, LineStyle style);
 
   void SetYAxisScale(AxisScale scale);
 
   void SetXAxisLabel(const std::string& label);
   std::string GetXAxisLabel() const;
 
   void SetYAxisLabel(const std::string& label);
   std::string GetYAxisLabel() const;
 
   void SetTitle(const std::string &title);
   std::string GetTitle() const;
 
   void SetLegendPosition(LegendPosition position);
   LegendPosition GetLegendPosition() const;
   std::string GetLegendPositionAsString() const;
 
   void SetShowLegend(bool show);
   bool GetShowLegend() const;
 
   void SetShowDataPoints(bool showDataPoints = false);
   bool GetShowDataPoints() const;
 
   void SetChartType(const std::string& label, QmitkChartWidget::ChartType chartType);
   std::string ConvertChartTypeToString(QmitkChartWidget::ChartType chartType) const;
 
   void ClearJavaScriptChart();
   void InitializeJavaScriptChart();
   void CallJavaScriptFuntion(const QString& command);
 
   QmitkChartData* GetC3Data() const;
   std::vector<QmitkChartxyData*>* GetC3xyData() const;
 
 private:
   std::string GetUniqueLabelName(const QList<QVariant>& labelList, const std::string& label) const;
   QmitkChartxyData* GetDataElementByLabel(const std::vector<QmitkChartxyData*>* c3xyData, const std::string& label) const;
   QList<QVariant> GetDataLabels(const std::vector<QmitkChartxyData*>* c3xyData) const;
 
   QWebChannel* m_WebChannel;
   QWebEngineView* m_WebEngineView;
 
   QmitkChartData * m_C3Data;
   std::vector<QmitkChartxyData*> * m_C3xyData;
   std::map<QmitkChartWidget::ChartType, std::string> m_ChartTypeToName;
   std::map<QmitkChartWidget::LegendPosition, std::string> m_LegendPositionToName;
   std::map<QmitkChartWidget::LineStyle, std::string> m_LineStyleToName;
   std::map<QmitkChartWidget::AxisScale, std::string> m_AxisScaleToName;
 };
 
 QmitkChartWidget::Impl::Impl(QWidget* parent)
   : m_WebChannel(new QWebChannel(parent))
   , m_WebEngineView(new QWebEngineView(parent))
 {
   //disable context menu for QWebEngineView
   m_WebEngineView->setContextMenuPolicy(Qt::NoContextMenu);
 
   //Set the webengineview to an initial empty page. The actual chart will be loaded once the data is calculated.
   m_WebEngineView->setUrl(QUrl(QStringLiteral("qrc:///C3js/empty.html")));
   m_WebEngineView->page()->setWebChannel(m_WebChannel);
 
   connect(m_WebEngineView, SIGNAL(loadFinished(bool)), parent, SLOT(OnLoadFinished(bool)));
 
   auto layout = new QGridLayout(parent);
   layout->setMargin(0);
   layout->addWidget(m_WebEngineView);
 
   parent->setLayout(layout);
 
   m_ChartTypeToName.emplace(ChartType::bar, "bar");
   m_ChartTypeToName.emplace(ChartType::line, "line");
   m_ChartTypeToName.emplace(ChartType::spline, "spline");
   m_ChartTypeToName.emplace(ChartType::pie, "pie");
   m_ChartTypeToName.emplace(ChartType::area, "area");
   m_ChartTypeToName.emplace(ChartType::area_spline  , "area-spline");
 
   m_LegendPositionToName.emplace(LegendPosition::bottom, "bottom");
   m_LegendPositionToName.emplace(LegendPosition::right, "right");
   m_LegendPositionToName.emplace(LegendPosition::inset, "inset");
 
   m_LineStyleToName.emplace(LineStyle::solid, "solid");
   m_LineStyleToName.emplace(LineStyle::dashed, "dashed");
 
   m_AxisScaleToName.emplace(AxisScale::linear, "");
   m_AxisScaleToName.emplace(AxisScale::log, "log");
 
   m_C3Data = new QmitkChartData();
   m_C3xyData = new std::vector<QmitkChartxyData*>();
 }
 
 QmitkChartWidget::Impl::~Impl()
 {
   delete m_C3Data;
   qDeleteAll(*m_C3xyData);
 
   delete m_C3xyData;
 }
 
 void QmitkChartWidget::Impl::AddData1D(const std::vector<double>& data1D, const std::string& label, QmitkChartWidget::ChartType type) {
   std::map<double, double> transformedData2D;
   unsigned int count = 0;
   //transform the 1D data to 2D data
   for (const auto& ele : data1D) {
     transformedData2D[count] = ele;
     count++;
   }
 
   this->AddData2D(transformedData2D, label, type);
 }
 
 void QmitkChartWidget::Impl::AddData2D(const std::map<double, double>& data2D, const std::string& label, QmitkChartWidget::ChartType type) {
   QMap<QVariant, QVariant> data2DConverted;
   for (const auto& aValue : data2D) {
     data2DConverted.insert(aValue.first, aValue.second);
   }
   const std::string chartTypeName(m_ChartTypeToName.at(type));
 
   auto definedLabels = GetDataLabels(GetC3xyData());
   auto uniqueLabel = GetUniqueLabelName(definedLabels, label);
 
   GetC3xyData()->push_back(new QmitkChartxyData(data2DConverted, QVariant(QString::fromStdString(uniqueLabel)), QVariant(QString::fromStdString(chartTypeName))));
 }
 
 void QmitkChartWidget::Impl::RemoveData(const std::string& label)
 {
   for (std::vector<QmitkChartxyData*>::iterator iter = GetC3xyData()->begin(); iter != GetC3xyData()->end(); ++iter)
   {
     const auto &temp = *iter;
     if (temp->GetLabel().toString().toStdString() == label)
     {
       delete temp;
       GetC3xyData()->erase(iter);
       return;
     }
   }
 
   throw std::invalid_argument("Cannot Remove Data because the label does not exist.");
 }
 
 void QmitkChartWidget::Impl::ClearData() {
   for (auto& xyData : *m_C3xyData)
   {
     m_WebChannel->deregisterObject(xyData);
     delete xyData;
     xyData = nullptr;
   }
   GetC3xyData()->clear();
 }
 
 std::string CheckForCorrectHex(const std::string& colorName)
 {
   std::regex rgx("([A-Fa-f0-9]{6}|[A-Fa-f0-9]{3})");
   std::smatch match;
 
   if (!colorName.empty() && colorName.at(0)!='#' && std::regex_search(colorName.begin(), colorName.end(), match, rgx))
   {
     return "#" + colorName;
   }
   else {
     return colorName;
   }
 }
 
 void QmitkChartWidget::Impl::SetColor(const std::string& label, const std::string& colorName)
 {
   auto element = GetDataElementByLabel(GetC3xyData(), label);
   if (element) {
     auto colorChecked = CheckForCorrectHex(colorName);
     element->SetColor(QVariant(QString::fromStdString(colorChecked)));
   }
 }
 
 void QmitkChartWidget::Impl::SetLineStyle(const std::string& label, LineStyle style) {
   auto element = GetDataElementByLabel(GetC3xyData(), label);
   //only has effect with chart type line
   if (element && element->GetChartType()==QVariant(QString::fromStdString(ConvertChartTypeToString(ChartType::line)))) {
     const std::string lineStyleName(m_LineStyleToName.at(style));
     element->SetLineStyle(QVariant(QString::fromStdString(lineStyleName)));
   }
 }
 
 void QmitkChartWidget::Impl::SetYAxisScale(AxisScale scale)
 {
   const std::string axisScaleName(m_AxisScaleToName.at(scale));
   GetC3Data()->SetYAxisScale(QString::fromStdString(axisScaleName));
 }
 
 QmitkChartxyData* QmitkChartWidget::Impl::GetDataElementByLabel(const std::vector<QmitkChartxyData*>* c3xyData, const std::string& label) const
 {
   for (auto element = c3xyData->begin(); element != c3xyData->end(); ++element) {
     if ((*element)->GetLabel().toString().toStdString() == label) {
       return *element;
     }
   }
   MITK_WARN << "label " << label << " not found in QmitkChartWidget";
   return nullptr;
 }
 
 QList<QVariant> QmitkChartWidget::Impl::GetDataLabels(const std::vector<QmitkChartxyData*>* c3xyData) const {
   QList<QVariant> dataLabels;
   for (auto element = c3xyData->begin(); element != c3xyData->end(); ++element) {
     dataLabels.push_back((*element)->GetLabel());
   }
   return dataLabels;
 }
 
 void QmitkChartWidget::Impl::SetXAxisLabel(const std::string& label) { 
   GetC3Data()->SetXAxisLabel(QString::fromStdString(label)); 
 }
 
 std::string QmitkChartWidget::Impl::GetXAxisLabel() const { 
   return GetC3Data()->GetXAxisLabel().toString().toStdString(); 
 }
 
 void QmitkChartWidget::Impl::SetYAxisLabel(const std::string& label) {
   GetC3Data()->SetYAxisLabel(QString::fromStdString(label)); 
 }
 
 std::string QmitkChartWidget::Impl::GetYAxisLabel() const { 
   return GetC3Data()->GetYAxisLabel().toString().toStdString(); 
 }
 
 void QmitkChartWidget::Impl::SetTitle(const std::string& title) {
   GetC3Data()->SetTitle(QString::fromStdString(title));
 }
 
 std::string QmitkChartWidget::Impl::GetTitle() const {
   return GetC3Data()->GetTitle().toString().toStdString();
 }
 
 void QmitkChartWidget::Impl::SetLegendPosition(QmitkChartWidget::LegendPosition legendPosition) {
   const std::string legendPositionName(m_LegendPositionToName.at(legendPosition));
   GetC3Data()->SetLegendPosition(QString::fromStdString(legendPositionName));
 }
 
 QmitkChartWidget::LegendPosition QmitkChartWidget::Impl::GetLegendPosition() const {
   for (const auto& aLegendPosition : m_LegendPositionToName) {
     if (aLegendPosition.second == GetLegendPositionAsString()) {
       return aLegendPosition.first;
     }
   }
   mitkThrow() << "can't find legend position!";
 }
 
 std::string QmitkChartWidget::Impl::GetLegendPositionAsString() const {
   return GetC3Data()->GetLegendPosition().toString().toStdString();
 }
 
 void QmitkChartWidget::Impl::SetShowLegend(bool show) {
   GetC3Data()->SetShowLegend(show);
 }
 
 bool QmitkChartWidget::Impl::GetShowLegend() const {
   return GetC3Data()->GetShowLegend().toBool();
 }
 
 void QmitkChartWidget::Impl::SetShowDataPoints(bool showDataPoints) {
   if (showDataPoints == true) {
     GetC3Data()->SetDataPointSize(3);
   }
   else {
     GetC3Data()->SetDataPointSize(0);
   }
 }
 
 bool QmitkChartWidget::Impl::GetShowDataPoints() const{
   int value = GetC3Data()->GetDataPointSize().toInt();
   if (value > 0) {
     return true;
   }
   else {
     return false;
   }
 }
 
 void QmitkChartWidget::Impl::SetChartType(const std::string& label, QmitkChartWidget::ChartType chartType) {
   auto element = GetDataElementByLabel(GetC3xyData(), label);
   if (element) {
     const std::string chartTypeName(m_ChartTypeToName.at(chartType));
     element->SetChartType(QVariant(QString::fromStdString(chartTypeName)));
   }
 }
 
 std::string QmitkChartWidget::Impl::ConvertChartTypeToString(QmitkChartWidget::ChartType chartType) const {
   return m_ChartTypeToName.at(chartType);
 }
 
 QmitkChartData* QmitkChartWidget::Impl::GetC3Data() const {
   return m_C3Data; 
 }
 
 std::vector<QmitkChartxyData*>* QmitkChartWidget::Impl::GetC3xyData() const {
   return m_C3xyData; 
 }
 
 void QmitkChartWidget::Impl::CallJavaScriptFuntion(const QString& command)
 {
   m_WebEngineView->page()->runJavaScript(command);
 }
 
 void QmitkChartWidget::Impl::ClearJavaScriptChart()
 {
   m_WebEngineView->setUrl(QUrl(QStringLiteral("qrc:///C3js/empty.html")));
 }
 
 void QmitkChartWidget::Impl::InitializeJavaScriptChart()
 {
   m_WebChannel->registerObject(QStringLiteral("chartData"), m_C3Data);
   unsigned count = 0;
   for (auto& xyData : *m_C3xyData) {
 	  QString variableName = "xyData" + QString::number(count);
 	  m_WebChannel->registerObject(variableName, xyData);
 	  count++;
   }
   m_WebEngineView->load(QUrl(QStringLiteral("qrc:///C3js/QmitkChartWidget.html")));
 }
 
 std::string QmitkChartWidget::Impl::GetUniqueLabelName(const QList<QVariant>& labelList, const std::string& label) const
 {
   QString currentLabel = QString::fromStdString(label);
   int counter = 0;
   while (labelList.contains(currentLabel))
   {
     currentLabel = QString::fromStdString(label + std::to_string(counter));
     counter++;
   }
   return currentLabel.toStdString();
 }
 
 QmitkChartWidget::QmitkChartWidget(QWidget* parent)
   : QWidget(parent),
   m_Impl(new Impl(this))
 {
 }
 
 QmitkChartWidget::~QmitkChartWidget()
 {
   delete m_Impl;
 }
 
 void QmitkChartWidget::AddData2D(const std::map<double, double>& data2D, const std::string& label, ChartType type)
 {
   m_Impl->AddData2D(data2D, label, type);
 }
 
 void QmitkChartWidget::SetColor(const std::string& label, const std::string& colorName)
 {
   m_Impl->SetColor(label, colorName);
 }
 
 void QmitkChartWidget::SetLineStyle(const std::string& label, LineStyle style)
 {
   m_Impl->SetLineStyle(label, style);
 }
 
 void QmitkChartWidget::SetYAxisScale(AxisScale scale)
 {
   m_Impl->SetYAxisScale(scale);
 }
 
 void QmitkChartWidget::AddData1D(const std::vector<double>& data1D, const std::string& label, ChartType type)
 {
   m_Impl->AddData1D(data1D, label, type);
 }
 
 void QmitkChartWidget::RemoveData(const std::string& label)
 {
   m_Impl->RemoveData(label);
 }
 
 void QmitkChartWidget::SetXAxisLabel(const std::string & label)
 {
 	m_Impl->SetXAxisLabel(label);
 }
 
 std::string QmitkChartWidget::GetXAxisLabel() const
 {
 	return m_Impl->GetXAxisLabel();
 }
 
 void QmitkChartWidget::SetYAxisLabel(const std::string & label)
 {
 	m_Impl->SetYAxisLabel(label);
 }
 
 std::string QmitkChartWidget::GetYAxisLabel() const
 {
 	return m_Impl->GetYAxisLabel();
 }
 
 void QmitkChartWidget::SetTitle(const std::string & title)
 {
   m_Impl->SetTitle(title);
 }
 
 std::string QmitkChartWidget::GetTitle() const
 {
   return m_Impl->GetTitle();
 }
 
 void QmitkChartWidget::SetShowDataPoints(bool showDataPoints)
 {
   m_Impl->SetShowDataPoints(showDataPoints);
 }
 
 bool QmitkChartWidget::GetShowDataPoints() const
 {
   return m_Impl->GetShowDataPoints();
 }
 
 void QmitkChartWidget::SetChartType(const std::string& label, ChartType type)
 {
   m_Impl->SetChartType(label, type);
 }
 
 void QmitkChartWidget::SetLegendPosition(LegendPosition position)
 {
   m_Impl->SetLegendPosition(position);
 }
 
 QmitkChartWidget::LegendPosition QmitkChartWidget::GetLegendPosition() const
 {
   return m_Impl->GetLegendPosition();
 }
 
 void QmitkChartWidget::SetShowLegend(bool show)
 {
   m_Impl->SetShowLegend(show);
 }
 
 bool QmitkChartWidget::GetShowLegend() const
 {
   return m_Impl->GetShowLegend();
 }
 
 void QmitkChartWidget::Show(bool showSubChart)
 {
   if (m_Impl->GetC3xyData()->empty()) {
     mitkThrow() << "no data available for display in chart";
   }
   this->m_Impl->GetC3Data()->SetAppearance(showSubChart, m_Impl->GetC3xyData()->front()->GetChartType()== QVariant("pie"));
   m_Impl->InitializeJavaScriptChart();
 }
 
 void QmitkChartWidget::Clear()
 {
-	m_Impl->ClearData();
+  //bug in Qt thats leads to crash in debug builds. Fixed in Qt 5.10
+  #if QT_VERSION >= QT_VERSION_CHECK(5, 10, 0)
+    m_Impl->ClearData();
+  #endif
 	m_Impl->ClearJavaScriptChart();
 }
 
 void QmitkChartWidget::OnLoadFinished(bool isLoadSuccessfull)
 {
   if(isLoadSuccessfull)
   {
     emit PageSuccessfullyLoaded();
   }
 }
 
 void QmitkChartWidget::SetChartTypeForAllDataAndReload(ChartType type)
 {
   auto allData = this->m_Impl->GetC3xyData();
   for (auto iterator = allData->begin(); iterator != allData->end(); ++iterator) {
     SetChartType((*iterator)->GetLabel().toString().toStdString(), type);
   }
   auto chartTypeName = m_Impl->ConvertChartTypeToString(type);
   const QString command = QString::fromStdString("transformView('" + chartTypeName + "')");
   m_Impl->CallJavaScriptFuntion(command);
 }
 
 void QmitkChartWidget::SetTheme(ChartStyle themeEnabled)
 {
   QString command;
   if (themeEnabled == ChartStyle::darkstyle)
   {
     command = QString("changeTheme('dark')");
   }
   else {
     command = QString("changeTheme('light')");
   }
   m_Impl->CallJavaScriptFuntion(command);
 }
 
 void QmitkChartWidget::Reload(bool showSubChart)
 {
   QString subChartString;
   if (showSubChart) {
     subChartString = "true";
   }
   else {
     subChartString = "false";
   }
   const QString command = QString("ReloadChart(" + subChartString + ")");
   m_Impl->CallJavaScriptFuntion(command);
 }
diff --git a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
index de1e68e5a5..1760aa1148 100644
--- a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
+++ b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsView.cpp
@@ -1,1293 +1,1303 @@
 /*===================================================================
 
 The Medical Imaging Interaction Toolkit (MITK)
 
 Copyright (c) German Cancer Research Center,
 Division of Medical and Biological Informatics.
 All rights reserved.
 
 This software is distributed WITHOUT ANY WARRANTY; without
 even the implied warranty of MERCHANTABILITY or FITNESS FOR
 A PARTICULAR PURPOSE.
 
 See LICENSE.txt or http://www.mitk.org for details.
 
 ===================================================================*/
 
 #include "QmitkImageStatisticsView.h"
 
 // Qt includes
 #include <QClipboard>
 #include <QScrollBar>
 #include <QVector>
 
 // berry includes
 #include <berryIWorkbenchPage.h>
 
 // mitk includes
 #include <mitkNodePredicateDataType.h>
 #include <mitkNodePredicateOr.h>
 #include <mitkPlanarFigureInteractor.h>
 #include <mitkImageTimeSelector.h>
 #include <QmitkRenderWindow.h>
 #include <QmitkChartWidget.h>
 #include <mitkImageCast.h>
 
 // itk includes
 #include "itksys/SystemTools.hxx"
 #include "itkImageRegionConstIteratorWithIndex.h"
 
 #include <limits>
 
 //blueberry includes
 #include <berryWorkbenchPlugin.h>
 #include <berryQtPreferences.h>
 
 const std::string QmitkImageStatisticsView::VIEW_ID = "org.mitk.views.imagestatistics";
 const int QmitkImageStatisticsView::STAT_TABLE_BASE_HEIGHT = 180;
 
 QmitkImageStatisticsView::QmitkImageStatisticsView(QObject* /*parent*/, const char* /*name*/)
 : m_Controls( nullptr ),
   m_SelectedImage( nullptr ),
   m_SelectedImageMask( nullptr ),
   m_SelectedPlanarFigure( nullptr ),
   m_ImageObserverTag( -1 ),
   m_ImageMaskObserverTag( -1 ),
   m_PlanarFigureObserverTag( -1 ),
   m_TimeObserverTag( -1 ),
   m_CurrentStatisticsValid( false ),
   m_StatisticsUpdatePending( false ),
   m_DataNodeSelectionChanged ( false ),
   m_Visible(false)
 {
   this->m_CalculationThread = new QmitkImageStatisticsCalculationThread;
 }
 
 QmitkImageStatisticsView::~QmitkImageStatisticsView()
 {
   if ( m_SelectedImage != nullptr )
     m_SelectedImage->RemoveObserver( m_ImageObserverTag );
   if ( m_SelectedImageMask != nullptr )
     m_SelectedImageMask->RemoveObserver( m_ImageMaskObserverTag );
   if ( m_SelectedPlanarFigure != nullptr )
     m_SelectedPlanarFigure->RemoveObserver( m_PlanarFigureObserverTag );
 
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
   delete this->m_CalculationThread;
 }
 
 
 void QmitkImageStatisticsView::CreateQtPartControl(QWidget *parent)
 {
   if (m_Controls == nullptr)
   {
     m_Controls = new Ui::QmitkImageStatisticsViewControls;
     m_Controls->setupUi(parent);
     CreateConnections();
 
     m_Controls->m_ErrorMessageLabel->hide();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_Controls->m_BinSizeFrame->setEnabled(false);
+    #if QT_VERSION < QT_VERSION_CHECK(5, 10, 0)
+      m_Controls->m_StatisticsWidgetStack->setVisible(false);
+      m_Controls->label_HistogramIsInvisibleWarning->setEnabled(true);
+      m_Controls->label_HistogramIsInvisibleWarning->setVisible(true);
+      m_Controls->label_HistogramIsInvisibleWarning->setText("<font color='red'>Histogram is not visible because Qt 5.10 is required. You can use the button <i>Copy to Clipboard</i> below to retrieve values.</font>");
+      m_Controls->groupBox_plot->setVisible(false);
+    #else
+      m_Controls->label_HistogramIsInvisibleWarning->setVisible(false);
+    #endif
+
   }
 }
 
 void QmitkImageStatisticsView::OnPageSuccessfullyLoaded()
 {
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   QString styleName = m_StylePref->Get(berry::QtPreferences::QT_STYLE_NAME, "");
 
   if (styleName == ":/org.blueberry.ui.qt/darkstyle.qss")
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::darkstyle);
   }
   else
   {
     this->m_Controls->m_JSHistogram->SetTheme(QmitkChartWidget::ChartStyle::lightstyle);
   }
 }
 
 void QmitkImageStatisticsView::CreateConnections()
 {
   if ( m_Controls )
   {
     connect( (QObject*)(this->m_Controls->m_ButtonCopyHistogramToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardHistogramButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_ButtonCopyStatisticsToClipboard), SIGNAL(clicked()),(QObject*) this, SLOT(OnClipboardStatisticsButtonClicked()) );
     connect( (QObject*)(this->m_Controls->m_IgnoreZerosCheckbox), SIGNAL(clicked()),(QObject*) this, SLOT(OnIgnoreZerosCheckboxClicked()) );
     connect( (QObject*) this->m_CalculationThread, SIGNAL(finished()),this, SLOT( OnThreadedStatisticsCalculationEnds()),Qt::QueuedConnection);
     connect( (QObject*) this, SIGNAL(StatisticsUpdate()),this, SLOT( RequestStatisticsUpdate()), Qt::QueuedConnection);
     connect( (QObject*) this->m_Controls->m_StatisticsTable, SIGNAL(cellDoubleClicked(int,int)),this, SLOT( JumpToCoordinates(int,int)) );
     connect((QObject*)(this->m_Controls->m_barRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnBarRadioButtonSelected()));
     connect((QObject*)(this->m_Controls->m_lineRadioButton), SIGNAL(clicked()), (QObject*)(this), SLOT(OnLineRadioButtonSelected()));
     connect( (QObject*) (this->m_Controls->m_HistogramNBinsSpinbox), SIGNAL(editingFinished()), this, SLOT(OnHistogramNBinsCheckBoxValueChanged()));
     connect((QObject*)(this->m_Controls->m_UseDefaultNBinsCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnDefaultNBinsSpinBoxChanged()));
     connect((QObject*)(this->m_Controls->m_ShowSubchartCheckBox), SIGNAL(clicked()), (QObject*) this, SLOT(OnShowSubchartBoxChanged()));
     connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   }
 }
 
 void QmitkImageStatisticsView::OnDefaultNBinsSpinBoxChanged()
 {
   if (this->m_Controls->m_UseDefaultNBinsCheckBox->isChecked()) {
     m_Controls->m_HistogramNBinsSpinbox->setValue(100);
     this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
     m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   }
   m_Controls->m_BinSizeFrame->setEnabled(!m_Controls->m_UseDefaultNBinsCheckBox->isChecked());
 
   this->UpdateStatistics();
 
 }
 
 void QmitkImageStatisticsView::OnShowSubchartBoxChanged()
 {
   bool showSubchart = this->m_Controls->m_ShowSubchartCheckBox->isChecked();
   this->m_Controls->m_JSHistogram->Reload(showSubchart);
 }
 
 
 void QmitkImageStatisticsView::OnBarRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::bar);
 }
 
 void QmitkImageStatisticsView::OnLineRadioButtonSelected()
 {
   this->m_Controls->m_JSHistogram->SetChartTypeForAllDataAndReload(QmitkChartWidget::ChartType::line);
 }
 
 void QmitkImageStatisticsView::PartClosed(const berry::IWorkbenchPartReference::Pointer& )
 {
 }
 
 void QmitkImageStatisticsView::OnTimeChanged(const itk::EventObject& e)
 {
   if (this->m_SelectedDataNodes.isEmpty() || this->m_SelectedImage == nullptr)
     return;
 
   const mitk::SliceNavigationController::GeometryTimeEvent* timeEvent =
       dynamic_cast<const mitk::SliceNavigationController::GeometryTimeEvent*>(&e);
   assert(timeEvent != nullptr);
   int timestep = timeEvent->GetPos();
 
   if (this->m_SelectedImage->GetTimeSteps() > 1)
   {
     for (int x = 0; x < this->m_Controls->m_StatisticsTable->columnCount(); x++)
     {
       for (int y = 0; y < this->m_Controls->m_StatisticsTable->rowCount(); y++)
       {
         QTableWidgetItem* item = this->m_Controls->m_StatisticsTable->item(y, x);
         if (item == nullptr)
           break;
 
         if (x == timestep)
         {
           item->setBackgroundColor(Qt::yellow);
         }
         else
         {
           if (y % 2 == 0)
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().base());
           else
             item->setBackground(this->m_Controls->m_StatisticsTable->palette().alternateBase());
         }
       }
     }
 
     this->m_Controls->m_StatisticsTable->viewport()->update();
   }
 
   if ((this->m_SelectedImage->GetTimeSteps() == 1 && timestep == 0) ||
       this->m_SelectedImage->GetTimeSteps() > 1)
   {
     // display histogram for selected timestep
     this->m_Controls->m_JSHistogram->Clear();
     QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer histogram =
         (QmitkImageStatisticsCalculationThread::HistogramType::ConstPointer)this->m_CalculationThread->GetTimeStepHistogram(timestep);
 
     if (histogram.IsNotNull())
     {
       bool closedFigure = this->m_CalculationThread->GetStatisticsUpdateSuccessFlag();
 
       if (closedFigure)
       {
 
         auto imageNameLabel = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         this->m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageNameLabel);
         if (this->m_Controls->m_lineRadioButton->isChecked())
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::line);
         }
         else
         {
           this->m_Controls->m_JSHistogram->SetChartType(imageNameLabel, QmitkChartWidget::ChartType::bar);
         }
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Grey value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         this->m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
       }
     }
   }
 }
 
 void QmitkImageStatisticsView::JumpToCoordinates(int row ,int col)
 {
   if(m_SelectedDataNodes.isEmpty())
   {
     MITK_WARN("QmitkImageStatisticsView") << "No data node selected for statistics calculation." ;
     return;
   }
 
   mitk::Point3D world;
   if (row==5 && !m_WorldMinList.empty())
     world = m_WorldMinList[col];
   else if (row==4 && !m_WorldMaxList.empty())
     world = m_WorldMaxList[col];
   else
     return;
 
   mitk::IRenderWindowPart* part = this->GetRenderWindowPart();
   if (part)
   {
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("sagittal")->GetSliceNavigationController()->SelectSliceByPoint(world);
     part->GetQmitkRenderWindow("coronal")->GetSliceNavigationController()->SelectSliceByPoint(world);
 
     mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(), col);
     part->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->SetGeometryTime(timeEvent);
   }
 }
 
 void QmitkImageStatisticsView::OnIgnoreZerosCheckboxClicked()
 {
   emit StatisticsUpdate();
 }
 
 void QmitkImageStatisticsView::OnClipboardHistogramButtonClicked()
 {
   if ( m_CurrentStatisticsValid && !( m_SelectedPlanarFigure != nullptr))
   {
     const unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
     typedef mitk::ImageStatisticsCalculator::HistogramType HistogramType;
     const HistogramType *histogram = this->m_CalculationThread->GetTimeStepHistogram(t).GetPointer();
 
     QString clipboard( "Measurement \t Frequency\n" );
     for ( HistogramType::ConstIterator it = histogram->Begin();
         it != histogram->End();
         ++it )
     {
       clipboard = clipboard.append( "%L1 \t %L2\n" )
                     .arg( it.GetMeasurementVector()[0], 0, 'f', 2 )
                     .arg( it.GetFrequency() );
     }
 
     QApplication::clipboard()->setText(
         clipboard, QClipboard::Clipboard );
   }
   // If a (non-closed) PlanarFigure is selected, display a line profile widget
   else if ( m_CurrentStatisticsValid && (m_SelectedPlanarFigure != nullptr ))
   {
     /*auto intensity = m_Controls->m_JSHistogram->GetFrequency();
     auto pixel = m_Controls->m_JSHistogram->GetMeasurement();
     QString clipboard( "Pixel \t Intensity\n" );
     auto j = pixel.begin();
     for (auto i = intensity.begin(); i < intensity.end(); i++)
     {
       assert(j != pixel.end());
       clipboard = clipboard.append( "%L1 \t %L2\n" )
                         .arg( (*j).toString())
                         .arg( (*i).toString());
       j++;
     }
 
     QApplication::clipboard()->setText(
         clipboard, QClipboard::Clipboard );
     */
   }
   else
   {
     QApplication::clipboard()->clear();
   }
 }
 
 void QmitkImageStatisticsView::OnClipboardStatisticsButtonClicked()
 {
   QLocale tempLocal;
   QLocale::setDefault(QLocale(QLocale::English, QLocale::UnitedStates));
   if ( m_CurrentStatisticsValid && !( m_SelectedPlanarFigure != nullptr))
    {
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics =
       this->m_CalculationThread->GetStatisticsData();
 
     // Set time borders for for loop ;)
     unsigned int startT, endT;
     if(this->m_Controls->m_CheckBox4dCompleteTable->checkState()==Qt::CheckState::Unchecked)
     {
         startT = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
           GetPos();
         endT = startT+1;
     }
     else
     {
         startT = 0;
         endT = statistics.size();
     }
     QVector< QVector<QString> > statisticsTable;
     QStringList headline{ "Timestep", "Mean", "Median", "StdDev", "RMS", "Max", "Min", "NumberOfVoxels", "Skewness", "Kurtosis", "Uniformity", "Entropy", "MPP", "UPP", "V [mm³]" };
 
     for(int i=0;i<headline.size();i++)
     {
         QVector<QString> row;
         row.append(headline.at(i));
         statisticsTable.append(row);
     }
 
     // Fill Table
     for(unsigned int t=startT;t<endT;t++)
     {
         // Copy statistics to clipboard ("%Ln" will use the default locale for
         // number formatting)
         QStringList value;
         value << QString::number(t)
               << QString::number(statistics[t]->GetMean())
               << QString::number(statistics[t]->GetMedian())
               << QString::number(statistics[t]->GetStd())
               << QString::number(statistics[t]->GetRMS())
               << QString::number(statistics[t]->GetMax())
               << QString::number(statistics[t]->GetMin())
               << QString::number(statistics[t]->GetN())
               << QString::number(statistics[t]->GetSkewness())
               << QString::number(statistics[t]->GetKurtosis())
               << QString::number(statistics[t]->GetUniformity())
               << QString::number(statistics[t]->GetEntropy())
               << QString::number(statistics[t]->GetMPP())
               << QString::number(statistics[t]->GetUPP())
               << QString::number(m_Controls->m_StatisticsTable->item(7, 0)->data(Qt::DisplayRole).toDouble());
 
          for(int z=0;z<value.size();z++)
          {
              statisticsTable[z].append(value.at(z));
          }
     }
 
     // Create output string
     QString clipboard;
     for(int i=0;i<statisticsTable.size();i++)
     {
         for(int t=0;t<statisticsTable.at(i).size();t++)
         {
             clipboard.append(statisticsTable.at(i).at(t));
             clipboard.append("\t");
         }
         clipboard.append("\n");
     }
     QApplication::clipboard()->setText(clipboard, QClipboard::Clipboard);
   }
   else
   {
     QApplication::clipboard()->clear();
   }
   QLocale::setDefault(tempLocal);
 }
 
 void QmitkImageStatisticsView::OnSelectionChanged( berry::IWorkbenchPart::Pointer /*part*/,
     const QList<mitk::DataNode::Pointer> &nodes )
 {
   if (this->m_Visible)
   {
     this->SelectionChanged( nodes );
   }
   else
   {
     this->m_DataNodeSelectionChanged = true;
   }
 }
 
 void QmitkImageStatisticsView::SelectionChanged(const QList<mitk::DataNode::Pointer> &selectedNodes)
 {
   //Clear Histogram if data node is deselected
   m_Controls->m_JSHistogram->Clear();
 
   if( this->m_StatisticsUpdatePending )
   {
     this->m_DataNodeSelectionChanged = true;
     return; // not ready for new data now!
   }
 
   if (selectedNodes.size() == this->m_SelectedDataNodes.size())
   {
     int i = 0;
     for (; i < selectedNodes.size(); ++i)
     {
       if (selectedNodes.at(i) != this->m_SelectedDataNodes.at(i))
       {
         break;
       }
     }
     // node selection did not change
     if (i == selectedNodes.size()) return;
   }
 
   //reset the feature image and image mask field
   m_Controls->m_SelectedFeatureImageLabel->setText("None");
   m_Controls->m_SelectedMaskLabel->setText("None");
 
   this->ReinitData();
   if (selectedNodes.isEmpty())
   {
     DisableHistogramGUIElements();
   }
   else
   {
     EnableHistogramGUIElements();
     ResetHistogramGUIElementsToDefault();
   }
   if(selectedNodes.size() == 1 || selectedNodes.size() == 2)
   {
     bool isBinary = false;
     selectedNodes.value(0)->GetBoolProperty("binary",isBinary);
     mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
     isBinary |= isLabelSet->CheckNode(selectedNodes.value(0));
     if(isBinary)
     {
       EnableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
     }
     for (int i= 0; i< selectedNodes.size(); ++i)
     {
       this->m_SelectedDataNodes.push_back(selectedNodes.at(i));
     }
     this->m_DataNodeSelectionChanged = false;
     this->m_Controls->m_ErrorMessageLabel->setText( "" );
     this->m_Controls->m_ErrorMessageLabel->hide();
     emit StatisticsUpdate();
   }
   else
   {
     this->m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::DisableHistogramGUIElements()
 {
   m_Controls->m_InfoLabel->setText("");
   m_Controls->groupBox_histogram->setEnabled(false);
   m_Controls->groupBox_statistics->setEnabled(false);
 }
 
 void QmitkImageStatisticsView::ResetHistogramGUIElementsToDefault()
 {
   m_Controls->m_barRadioButton->setChecked(true);
   m_Controls->m_HistogramNBinsSpinbox->setValue(100);
   m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
   m_Controls->m_UseDefaultNBinsCheckBox->setChecked(true);
   m_Controls->m_ShowSubchartCheckBox->setChecked(true);
   m_Controls->m_BinSizeFrame->setEnabled(false);
   m_Controls->m_barRadioButton->setEnabled(true);
   m_Controls->m_lineRadioButton->setEnabled(true);
   m_Controls->m_HistogramNBinsSpinbox->setEnabled(true);
   this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
 }
 
 void QmitkImageStatisticsView::EnableHistogramGUIElements()
 {
   m_Controls->groupBox_histogram->setEnabled(true);
   m_Controls->groupBox_plot->setEnabled(true);
   m_Controls->groupBox_statistics->setEnabled(true);
 }
 
 void QmitkImageStatisticsView::ReinitData()
 {
   while( this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if(this->m_SelectedImage != nullptr)
   {
     this->m_SelectedImage->RemoveObserver( this->m_ImageObserverTag);
     this->m_SelectedImage = nullptr;
   }
   if(this->m_SelectedImageMask != nullptr)
   {
     this->m_SelectedImageMask->RemoveObserver( this->m_ImageMaskObserverTag);
     this->m_SelectedImageMask = nullptr;
   }
   if(this->m_SelectedPlanarFigure != nullptr)
   {
     this->m_SelectedPlanarFigure->RemoveObserver( this->m_PlanarFigureObserverTag);
     this->m_SelectedPlanarFigure = nullptr;
   }
   this->m_SelectedDataNodes.clear();
   this->m_StatisticsUpdatePending = false;
 
   m_Controls->m_ErrorMessageLabel->setText( "" );
   m_Controls->m_ErrorMessageLabel->hide();
   this->InvalidateStatisticsTableView();
   m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
 }
 
 void QmitkImageStatisticsView::OnThreadedStatisticsCalculationEnds()
 {
   m_Controls->m_ErrorMessageLabel->setText("");
   m_Controls->m_ErrorMessageLabel->hide();
   this->WriteStatisticsToGUI();
 }
 
 void QmitkImageStatisticsView::UpdateStatistics()
 {
   mitk::IRenderWindowPart* renderPart = this->GetRenderWindowPart();
   if ( renderPart == nullptr )
   {
     this->m_StatisticsUpdatePending =  false;
     return;
   }
   m_WorldMinList.clear();
   m_WorldMaxList.clear();
 
   // classify selected nodes
   mitk::NodePredicateDataType::Pointer isImage = mitk::NodePredicateDataType::New("Image");
   mitk::NodePredicateDataType::Pointer isLabelSet = mitk::NodePredicateDataType::New("LabelSetImage");
   mitk::NodePredicateOr::Pointer imagePredicate = mitk::NodePredicateOr::New(isImage, isLabelSet);
 
   std::string maskName;
   std::string maskType;
   std::string featureImageName;
   unsigned int maskDimension = 0;
 
   // reset data from last run
   ITKCommandType::Pointer changeListener = ITKCommandType::New();
   changeListener->SetCallbackFunction( this, &QmitkImageStatisticsView::SelectedDataModified );
 
   mitk::DataNode::Pointer planarFigureNode;
   for( int i= 0 ; i < this->m_SelectedDataNodes.size(); ++i)
   {
     mitk::PlanarFigure::Pointer planarFig = dynamic_cast<mitk::PlanarFigure*>(this->m_SelectedDataNodes.at(i)->GetData());
     if( imagePredicate->CheckNode(this->m_SelectedDataNodes.at(i)) )
     {
       bool isMask = false;
       this->m_SelectedDataNodes.at(i)->GetPropertyValue("binary", isMask);
       isMask |= isLabelSet->CheckNode(this->m_SelectedDataNodes.at(i));
 
       if( this->m_SelectedImageMask == nullptr && isMask)
       {
         this->m_SelectedImageMask = dynamic_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
         this->m_ImageMaskObserverTag = this->m_SelectedImageMask->AddObserver(itk::ModifiedEvent(), changeListener);
 
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = m_SelectedImageMask->GetNameOfClass();
         maskDimension = 3;
       }
       else if( !isMask )
       {
         if(this->m_SelectedImage == nullptr)
         {
           this->m_SelectedImage = static_cast<mitk::Image*>(this->m_SelectedDataNodes.at(i)->GetData());
           this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
         }
         featureImageName = this->m_SelectedDataNodes.at(i)->GetName();
       }
     }
     else if (planarFig.IsNotNull())
     {
       if(this->m_SelectedPlanarFigure == nullptr)
       {
         this->m_SelectedPlanarFigure = planarFig;
         this->m_PlanarFigureObserverTag  =
             this->m_SelectedPlanarFigure->AddObserver(mitk::EndInteractionPlanarFigureEvent(), changeListener);
         maskName = this->m_SelectedDataNodes.at(i)->GetName();
         maskType = this->m_SelectedPlanarFigure->GetNameOfClass();
         maskDimension = 2;
         planarFigureNode = m_SelectedDataNodes.at(i);
       }
     }
     else
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Invalid data node type!</font>");
       m_Controls->m_ErrorMessageLabel->show();
     }
   }
 
   if(maskName == "")
   {
     maskName = "None";
     maskType = "";
     maskDimension = 0;
   }
 
   if(featureImageName == "")
   {
     featureImageName = "None";
   }
 
   if (m_SelectedPlanarFigure != nullptr && m_SelectedImage == nullptr)
   {
     mitk::DataStorage::SetOfObjects::ConstPointer parentSet = this->GetDataStorage()->GetSources(planarFigureNode);
     for (unsigned int i=0; i<parentSet->Size(); i++)
     {
       mitk::DataNode::Pointer node = parentSet->ElementAt(i);
       if( imagePredicate->CheckNode(node) )
       {
         bool isMask = false;
         node->GetPropertyValue("binary", isMask);
         isMask |= isLabelSet->CheckNode(node);
 
         if( !isMask )
         {
           if(this->m_SelectedImage == nullptr)
           {
             this->m_SelectedImage = static_cast<mitk::Image*>(node->GetData());
             this->m_ImageObserverTag = this->m_SelectedImage->AddObserver(itk::ModifiedEvent(), changeListener);
           }
         }
       }
     }
   }
 
   unsigned int timeStep = renderPart->GetTimeNavigationController()->GetTime()->GetPos();
 
   if ( m_SelectedImage != nullptr && m_SelectedImage->IsInitialized())
   {
     // Check if a the selected image is a multi-channel image. If yes, statistics
     // cannot be calculated currently.
     if ( m_SelectedImage->GetPixelType().GetNumberOfComponents() > 1 )
     {
       m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Multi-component images not supported.</font>" );
       m_Controls->m_ErrorMessageLabel->show();
 
       this->InvalidateStatisticsTableView();
       m_Controls->m_StatisticsWidgetStack->setCurrentIndex( 0 );
       m_CurrentStatisticsValid = false;
       this->m_StatisticsUpdatePending = false;
       this->DisableHistogramGUIElements();
       m_Controls->m_InfoLabel->setText("");
       return;
     }
 
     std::stringstream maskLabel;
     maskLabel << maskName;
     if ( maskDimension > 0 )
     {
       maskLabel << "  [" << maskDimension << "D " << maskType << "]";
     }
     m_Controls->m_SelectedMaskLabel->setText( maskLabel.str().c_str() );
     m_Controls->m_SelectedFeatureImageLabel->setText(featureImageName.c_str());
 
     // check time step validity
     if(m_SelectedImage->GetDimension() <= 3 && timeStep > m_SelectedImage->GetDimension(3)-1)
     {
       timeStep = m_SelectedImage->GetDimension(3)-1;
     }
 
     // Add the used mask time step to the mask label so the user knows which mask time step was used
     // if the image time step is bigger than the total number of mask time steps (see
     // ImageStatisticsCalculator::ExtractImageAndMask)
     if (m_SelectedImageMask != nullptr)
     {
       unsigned int maskTimeStep = timeStep;
 
       if (maskTimeStep >= m_SelectedImageMask->GetTimeSteps())
       {
         maskTimeStep = m_SelectedImageMask->GetTimeSteps() - 1;
       }
 
       m_Controls->m_SelectedMaskLabel->setText(m_Controls->m_SelectedMaskLabel->text() +
           QString(" (t=") +
           QString::number(maskTimeStep) +
           QString(")"));
     }
 
     // check if the segmentation mask is empty
     if (m_SelectedImageMask != NULL)
     {
       typedef itk::Image<unsigned char, 3> ItkImageType;
       typedef itk::ImageRegionConstIteratorWithIndex< ItkImageType > IteratorType;
 
       ItkImageType::Pointer itkImage;
 
       mitk::CastToItkImage( m_SelectedImageMask, itkImage );
 
       bool empty = true;
       IteratorType it( itkImage, itkImage->GetLargestPossibleRegion() );
       while ( !it.IsAtEnd() )
       {
         ItkImageType::ValueType val = it.Get();
         if ( val != 0 )
         {
           empty = false;
           break;
         }
         ++it;
       }
 
       if ( empty )
       {
         m_Controls->m_ErrorMessageLabel->setText( "<font color='red'>Empty segmentation mask selected...</font>" );
         m_Controls->m_ErrorMessageLabel->show();
 
         return;
       }
     }
 
     //// initialize thread and trigger it
     this->m_CalculationThread->SetIgnoreZeroValueVoxel( m_Controls->m_IgnoreZerosCheckbox->isChecked() );
     this->m_CalculationThread->Initialize( m_SelectedImage, m_SelectedImageMask, m_SelectedPlanarFigure );
     this->m_CalculationThread->SetTimeStep( timeStep );
 
     m_Controls->m_ErrorMessageLabel->setText("<font color='red'>Calculating statistics...</font>");
     m_Controls->m_ErrorMessageLabel->show();
 
     try
     {
       // Compute statistics
       this->m_CalculationThread->start();
     }
     catch ( const mitk::Exception& e)
     {
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.GetDescription()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::runtime_error &e )
     {
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
     catch ( const std::exception &e )
     {
       MITK_ERROR << "Caught exception: " << e.what();
 
       // In case of exception, print error message on GUI
       m_Controls->m_ErrorMessageLabel->setText("<font color='red'>" + QString(e.what()) + "</font>");
       m_Controls->m_ErrorMessageLabel->show();
       this->m_StatisticsUpdatePending = false;
     }
   }
   else
   {
     this->m_StatisticsUpdatePending = false;
   }
 }
 
 void QmitkImageStatisticsView::SelectedDataModified()
 {
   if( !m_StatisticsUpdatePending )
   {
     emit StatisticsUpdate();
   }
 }
 
 void QmitkImageStatisticsView::NodeRemoved(const mitk::DataNode *node)
 {
   while(this->m_CalculationThread->isRunning()) // wait until thread has finished
   {
     itksys::SystemTools::Delay(100);
   }
 
   if (node->GetData() == m_SelectedImage)
   {
     m_SelectedImage = nullptr;
   }
 }
 
 void QmitkImageStatisticsView::RequestStatisticsUpdate()
 {
   if ( !m_StatisticsUpdatePending )
   {
     if(this->m_DataNodeSelectionChanged)
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->m_StatisticsUpdatePending = true;
       this->UpdateStatistics();
     }
   }
   if (this->GetRenderWindowPart())
     this->GetRenderWindowPart()->RequestUpdate();
 }
 
 void QmitkImageStatisticsView::OnHistogramNBinsCheckBoxValueChanged()
 {
     if (static_cast<unsigned int>(m_Controls->m_HistogramNBinsSpinbox->value()) != m_HistogramNBins)
     {
       m_HistogramNBins = m_Controls->m_HistogramNBinsSpinbox->value();
         this->m_CalculationThread->SetHistogramNBins(m_Controls->m_HistogramNBinsSpinbox->value());
         this->UpdateStatistics();
     }
 }
 
 void QmitkImageStatisticsView::WriteStatisticsToGUI()
 {
   m_Controls->m_JSHistogram->Clear();
 
   //Disconnect OnLineRadioButtonSelected() to prevent reloading chart when radiobutton is checked programmatically
   disconnect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), 0, 0);
   connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnPageSuccessfullyLoaded()));
   m_Controls->m_InfoLabel->setText("");
 
   if (m_DataNodeSelectionChanged)
   {
     this->m_StatisticsUpdatePending = false;
     this->RequestStatisticsUpdate();
     return;    // stop visualization of results and calculate statistics of new selection
   }
 
   if (this->m_CalculationThread->GetStatisticsUpdateSuccessFlag())
   {
     if (this->m_CalculationThread->GetStatisticsChangedFlag())
     {
       // Do not show any error messages
       m_Controls->m_ErrorMessageLabel->hide();
       m_CurrentStatisticsValid = true;
     }
 
     if (m_SelectedImage != nullptr) {
       //all statistics are now computed also on planar figures (lines, paths...)!
     // If a (non-closed) PlanarFigure is selected, display a line profile widget
       if (m_SelectedPlanarFigure != nullptr) {
         // Check if the (closed) planar figure is out of bounds and so no image mask could be calculated--> Intensity Profile can not be calculated
         bool outOfBounds = false;
         if (m_SelectedPlanarFigure->IsClosed() && m_SelectedImageMask == nullptr)
         {
           outOfBounds = true;
           const QString message("<font color='red'>Planar figure is on a rotated image plane or outside the image bounds.</font>");
           m_Controls->m_InfoLabel->setText(message);
         }
 
         // check whether PlanarFigure is initialized
         const mitk::PlaneGeometry *planarFigurePlaneGeometry = m_SelectedPlanarFigure->GetPlaneGeometry();
 
         if (!(planarFigurePlaneGeometry == nullptr || outOfBounds))
         {
           unsigned int timeStep = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->GetPos();
 
           mitk::Image::Pointer image;
 
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4)
           {
             mitk::ImageTimeSelector::Pointer timeSelector = mitk::ImageTimeSelector::New();
             timeSelector->SetInput(this->m_CalculationThread->GetStatisticsImage());
             timeSelector->SetTimeNr(timeStep);
             timeSelector->Update();
 
             image = timeSelector->GetOutput();
           }
           else
           {
             image = this->m_CalculationThread->GetStatisticsImage();
           }
 
           mitk::IntensityProfile::ConstPointer intensityProfile = (mitk::IntensityProfile::ConstPointer)mitk::ComputeIntensityProfile(image, m_SelectedPlanarFigure);
 
           auto intensityProfileList = ConvertIntensityProfileToVector(intensityProfile);
           auto lineDataLabel = "Intensity profile " + m_Controls->m_SelectedMaskLabel->text().toStdString();
           m_Controls->m_JSHistogram->SetChartType(lineDataLabel, QmitkChartWidget::ChartType::line);
           m_Controls->m_JSHistogram->AddData1D(intensityProfileList, lineDataLabel);
           m_Controls->m_JSHistogram->SetXAxisLabel("Distance");
           m_Controls->m_JSHistogram->SetYAxisLabel("Intensity");
           m_Controls->m_JSHistogram->Show(m_Controls->m_ShowSubchartCheckBox->isChecked());
 
           m_Controls->m_lineRadioButton->setChecked(true);
           m_Controls->m_lineRadioButton->setEnabled(false);
           m_Controls->m_barRadioButton->setEnabled(false);
           m_Controls->m_HistogramNBinsSpinbox->setEnabled(false);
           m_Controls->m_BinSizeFrame->setEnabled(false);
           m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(false);
 
           //Reconnect OnLineRadioButtonSelected()
           connect((QObject*)(this->m_Controls->m_JSHistogram), SIGNAL(PageSuccessfullyLoaded()), (QObject*) this, SLOT(OnLineRadioButtonSelected()));
           auto statisticsVector = this->m_CalculationThread->GetStatisticsData();
           //only one entry (current timestep)
           this->FillLinearProfileStatisticsTableView(statisticsVector.front().GetPointer(), this->m_CalculationThread->GetStatisticsImage());
 
           QString message("<font color='red'>Only linegraph available for an intensity profile!");
           if (this->m_CalculationThread->GetStatisticsImage()->GetDimension() == 4) {
             message += "Only current timestep displayed!";
           }
           message += "</font>";
           m_Controls->m_InfoLabel->setText(message);
           m_CurrentStatisticsValid = true;
         }
         else
         {
           // Clear statistics, histogram, and GUI
           this->InvalidateStatisticsTableView();
           m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
           m_CurrentStatisticsValid = false;
           m_Controls->m_ErrorMessageLabel->hide();
           m_Controls->m_SelectedMaskLabel->setText("None");
           this->m_StatisticsUpdatePending = false;
           if (!outOfBounds)
             m_Controls->m_InfoLabel->setText("");
           return;
         }
       }
       else
       {
         m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
 
         auto histogram = this->m_CalculationThread->GetTimeStepHistogram(this->m_CalculationThread->GetTimeStep()).GetPointer();
 
         auto imageLabelName = m_Controls->m_SelectedFeatureImageLabel->text().toStdString();
         m_Controls->m_JSHistogram->AddData2D(ConvertHistogramToMap(histogram), imageLabelName);
         m_Controls->m_JSHistogram->SetChartType(imageLabelName, QmitkChartWidget::ChartType::bar);
         this->m_Controls->m_JSHistogram->SetXAxisLabel("Gray value");
         this->m_Controls->m_JSHistogram->SetYAxisLabel("Frequency");
         m_Controls->m_UseDefaultNBinsCheckBox->setEnabled(true);
         m_Controls->m_JSHistogram->Show(this->m_Controls->m_ShowSubchartCheckBox->isChecked());
         this->FillStatisticsTableView(this->m_CalculationThread->GetStatisticsData(), this->m_CalculationThread->GetStatisticsImage());
       }
       m_CurrentStatisticsValid = true;
     }
   }
   else
   {
     m_Controls->m_SelectedMaskLabel->setText("None");
     m_Controls->m_ErrorMessageLabel->setText(m_CalculationThread->GetLastErrorMessage().c_str());
     m_Controls->m_ErrorMessageLabel->show();
 
     // Clear statistics and histogram
     this->InvalidateStatisticsTableView();
     m_Controls->m_StatisticsWidgetStack->setCurrentIndex(0);
     m_CurrentStatisticsValid = false;
 
   }
   berry::IPreferencesService* prefService = berry::WorkbenchPlugin::GetDefault()->GetPreferencesService();
   m_StylePref = prefService->GetSystemPreferences()->Node(berry::QtPreferences::QT_STYLES_NODE);
 
   this->m_StatisticsUpdatePending = false;
 }
 
 void QmitkImageStatisticsView::FillStatisticsTableView(
     const std::vector<mitk::ImageStatisticsCalculator::StatisticsContainer::Pointer> &statistics,
     const mitk::Image *image )
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(image->GetTimeSteps());
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(image->GetTimeSteps() > 1);
 
   // Set Checkbox for complete copy of statistic table
   if(image->GetTimeSteps()>1)
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(true);
   }
   else
   {
     this->m_Controls->m_CheckBox4dCompleteTable->setEnabled(false);
     this->m_Controls->m_CheckBox4dCompleteTable->setChecked(false);
   }
 
 
   for (unsigned int t = 0; t < image->GetTimeSteps(); t++)
   {
     this->m_Controls->m_StatisticsTable->setHorizontalHeaderItem(t,
         new QTableWidgetItem(QString::number(t)));
 
     if (statistics.at(t)->GetMaxIndex().size()==3)
     {
       mitk::Point3D index, max, min;
       index[0] = statistics.at(t)->GetMaxIndex()[0];
       index[1] = statistics.at(t)->GetMaxIndex()[1];
       index[2] = statistics.at(t)->GetMaxIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, max);
       this->m_WorldMaxList.push_back(max);
       index[0] = statistics.at(t)->GetMinIndex()[0];
       index[1] = statistics.at(t)->GetMinIndex()[1];
       index[2] = statistics.at(t)->GetMinIndex()[2];
       m_SelectedImage->GetGeometry()->IndexToWorld(index, min);
       this->m_WorldMinList.push_back(min);
     }
 
     auto statisticsVector = AssembleStatisticsIntoVector(statistics.at(t).GetPointer(), image);
 
     unsigned int count = 0;
     for (const auto& entry : statisticsVector) {
       auto item = new QTableWidgetItem(entry);
       this->m_Controls->m_StatisticsTable->setItem(count, t, item);
       count++;
     }
 
     }
 
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 
   // make sure the current timestep's column is highlighted (and the correct histogram is displayed)
   unsigned int t = this->GetRenderWindowPart()->GetTimeNavigationController()->GetTime()->
       GetPos();
   mitk::SliceNavigationController::GeometryTimeEvent timeEvent(this->m_SelectedImage->GetTimeGeometry(),
       t);
   this->OnTimeChanged(timeEvent);
 
   t = std::min(image->GetTimeSteps() - 1, t);
 
   // See bug 18340
   /*QString hotspotMean; hotspotMean.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMean(), 0, 'f', decimals));
   hotspotMean += " (";
   for (int i=0; i<s[t].GetHotspotIndex().size(); i++)
   {
   hotspotMean += QString::number(s[t].GetHotspotIndex()[i]);
   if (i<s[t].GetHotspotIndex().size()-1)
   hotspotMean += ",";
   }
   hotspotMean += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 7, t, new QTableWidgetItem( hotspotMean ) );
 
   QString hotspotMax; hotspotMax.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMax(), 0, 'f', decimals));
   hotspotMax += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMaxIndex().size(); i++)
   {
   hotspotMax += QString::number(s[t].GetHotspotStatistics().GetMaxIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMaxIndex().size()-1)
   hotspotMax += ",";
   }
   hotspotMax += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 8, t, new QTableWidgetItem( hotspotMax ) );
 
   QString hotspotMin; hotspotMin.append(QString("%1").arg(s[t].GetHotspotStatistics().GetMin(), 0, 'f', decimals));
   hotspotMin += " (";
   for (int i=0; i<s[t].GetHotspotStatistics().GetMinIndex().size(); i++)
   {
   hotspotMin += QString::number(s[t].GetHotspotStatistics().GetMinIndex()[i]);
   if (i<s[t].GetHotspotStatistics().GetMinIndex().size()-1)
   hotspotMin += ",";
   }
   hotspotMin += ")";
 
   this->m_Controls->m_StatisticsTable->setItem( 9, t, new QTableWidgetItem( hotspotMin ) );*/
 }
 
 std::vector<QString> QmitkImageStatisticsView::AssembleStatisticsIntoVector(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics, mitk::Image::ConstPointer image, bool noVolumeDefined) const
 {
   std::vector<QString> result;
 
   unsigned int decimals = 2;
 
   //statistics of higher order should have 5 decimal places because they used to be very small
   unsigned int decimalsHigherOrderStatistics = 5;
 
   if (image->GetPixelType().GetComponentType() == itk::ImageIOBase::DOUBLE || image->GetPixelType().GetComponentType() == itk::ImageIOBase::FLOAT)
   {
     decimals = 5;
   }
 
   result.push_back(GetFormattedString(statistics->GetMean(), decimals));
   result.push_back(GetFormattedString(statistics->GetMedian(), decimals));
   result.push_back(GetFormattedString(statistics->GetStd(), decimals));
   result.push_back(GetFormattedString(statistics->GetRMS(), decimals));
   result.push_back(GetFormattedString(statistics->GetMax(), decimals) + " " + GetFormattedIndex(statistics->GetMaxIndex()));
   result.push_back(GetFormattedString(statistics->GetMin(), decimals) + " " + GetFormattedIndex(statistics->GetMinIndex()));
   //to prevent large negative values of empty image statistics
   if (statistics->GetN() != std::numeric_limits<long>::min()) {
     result.push_back(GetFormattedString(statistics->GetN(), 0));
 
     const mitk::BaseGeometry *geometry = image->GetGeometry();
     if (geometry != NULL && !noVolumeDefined)
   {
       const mitk::Vector3D &spacing = image->GetGeometry()->GetSpacing();
       double volume = spacing[0] * spacing[1] * spacing[2] * static_cast<double>(statistics->GetN());
       result.push_back(GetFormattedString(volume, decimals));
   }
     else {
       result.push_back("NA");
   }
   }
   else {
     result.push_back("NA");
     result.push_back("NA");
   }
 
   result.push_back(GetFormattedString(statistics->GetSkewness(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetKurtosis(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetUniformity(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetEntropy(), decimalsHigherOrderStatistics));
   result.push_back(GetFormattedString(statistics->GetMPP(), decimals));
   result.push_back(GetFormattedString(statistics->GetUPP(), decimalsHigherOrderStatistics));
 
   return result;
 }
 
 void QmitkImageStatisticsView::FillLinearProfileStatisticsTableView(mitk::ImageStatisticsCalculator::StatisticsContainer::ConstPointer statistics,
   const mitk::Image *image)
 {
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
 
   m_PlanarFigureStatistics = this->AssembleStatisticsIntoVector(statistics, image, true);
 
   for (unsigned int i = 0; i< m_PlanarFigureStatistics.size(); i++)
   {
     this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem(m_PlanarFigureStatistics[i] ));
   }
 
   this->m_Controls->m_StatisticsTable->resizeColumnsToContents();
   int height = STAT_TABLE_BASE_HEIGHT;
 
   if (this->m_Controls->m_StatisticsTable->horizontalHeader()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalHeader()->height();
 
   if (this->m_Controls->m_StatisticsTable->horizontalScrollBar()->isVisible())
     height += this->m_Controls->m_StatisticsTable->horizontalScrollBar()->height();
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(height);
 }
 
 void QmitkImageStatisticsView::InvalidateStatisticsTableView()
 {
   this->m_Controls->m_StatisticsTable->horizontalHeader()->setVisible(false);
   this->m_Controls->m_StatisticsTable->setColumnCount(1);
 
   for ( int i = 0; i < this->m_Controls->m_StatisticsTable->rowCount(); ++i )
   {
     {
       this->m_Controls->m_StatisticsTable->setItem( i, 0, new QTableWidgetItem( "NA" ) );
     }
   }
 
   this->m_Controls->m_StatisticsTable->setMinimumHeight(STAT_TABLE_BASE_HEIGHT);
 }
 
 void QmitkImageStatisticsView::Activated()
 {
 }
 
 void QmitkImageStatisticsView::Deactivated()
 {
 }
 
 void QmitkImageStatisticsView::Visible()
 {
   m_Visible = true;
 
   mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
   if (renderWindow)
   {
     itk::ReceptorMemberCommand<QmitkImageStatisticsView>::Pointer cmdTimeEvent =
         itk::ReceptorMemberCommand<QmitkImageStatisticsView>::New();
     cmdTimeEvent->SetCallbackFunction(this, &QmitkImageStatisticsView::OnTimeChanged);
 
     // It is sufficient to add the observer to the axial render window since the GeometryTimeEvent
     // is always triggered by all views.
     m_TimeObserverTag = renderWindow->GetQmitkRenderWindow("axial")->
         GetSliceNavigationController()->
         AddObserver(mitk::SliceNavigationController::GeometryTimeEvent(nullptr, 0), cmdTimeEvent);
   }
 
   if (m_DataNodeSelectionChanged)
   {
     if (this->IsCurrentSelectionValid())
     {
       this->SelectionChanged(this->GetCurrentSelection());
     }
     else
     {
       this->SelectionChanged(this->GetDataManagerSelection());
     }
     m_DataNodeSelectionChanged = false;
   }
 }
 
 void QmitkImageStatisticsView::Hidden()
 {
   m_Visible = false;
 
   // The slice navigation controller observer is removed here instead of in the destructor.
   // If it was called in the destructor, the application would freeze because the view's
   // destructor gets called after the render windows have been destructed.
   if ( m_TimeObserverTag != 0 )
   {
     mitk::IRenderWindowPart* renderWindow = GetRenderWindowPart();
 
     if (renderWindow)
     {
       renderWindow->GetQmitkRenderWindow("axial")->GetSliceNavigationController()->
           RemoveObserver( m_TimeObserverTag );
     }
     m_TimeObserverTag = 0;
   }
 }
 
 void QmitkImageStatisticsView::SetFocus()
 {
 }
 
 std::map<double, double> QmitkImageStatisticsView::ConvertHistogramToMap(itk::Statistics::Histogram<double>::ConstPointer histogram) const
 {
   std::map<double, double> histogramMap;
 
 	auto endIt = histogram->End();
 	auto it = histogram->Begin();
 
 	// generating Lists of measurement and frequencies
   for (; it != endIt; ++it)
 	{
     double frequency = it.GetFrequency();
     double measurement = it.GetMeasurementVector()[0];
     histogramMap.emplace(measurement, frequency);
 	}
 
 	return histogramMap;
 }
 
 std::vector<double> QmitkImageStatisticsView::ConvertIntensityProfileToVector(mitk::IntensityProfile::ConstPointer intensityProfile) const
 {
   std::vector<double> intensityProfileList;
   auto end = intensityProfile->End();
 
 	for (auto it = intensityProfile->Begin(); it != end; ++it)
 	{
     intensityProfileList.push_back(it.GetMeasurementVector()[0]);
 	}
 	return intensityProfileList;
 }
 
 QString QmitkImageStatisticsView::GetFormattedString(double value, unsigned int decimals) const
 {
   typedef mitk::ImageStatisticsCalculator::StatisticsContainer::RealType RealType;
   RealType maxVal = std::numeric_limits<RealType>::max();
 
   if (value == maxVal)
   {
     return QString("NA");
   }
   else
   {
     return QString("%1").arg(value, 0, 'f', decimals);
   }
 }
 
 QString QmitkImageStatisticsView::GetFormattedIndex(const vnl_vector<int>& vector) const
 {
   if (vector.empty()) {
     return QString();
   }
   QString formattedIndex("(");
   for (const auto& entry : vector)
   {
     formattedIndex += QString::number(entry);
     formattedIndex += ",";
   }
   formattedIndex.chop(1);
   formattedIndex += ")";
   return formattedIndex;
 }
diff --git a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsViewControls.ui b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsViewControls.ui
index 7475b0623e..ae99157bb2 100644
--- a/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsViewControls.ui
+++ b/Plugins/org.mitk.gui.qt.measurementtoolbox/src/internal/QmitkImageStatisticsViewControls.ui
@@ -1,649 +1,750 @@
 <?xml version="1.0" encoding="UTF-8"?>
 <ui version="4.0">
  <class>QmitkImageStatisticsViewControls</class>
  <widget class="QWidget" name="QmitkImageStatisticsViewControls">
   <property name="enabled">
    <bool>true</bool>
   </property>
   <property name="geometry">
    <rect>
     <x>0</x>
     <y>0</y>
     <width>548</width>
     <height>812</height>
    </rect>
   </property>
   <property name="windowTitle">
    <string>Form</string>
   </property>
   <layout class="QVBoxLayout" name="verticalLayout_4">
    <item>
     <layout class="QGridLayout" name="gridLayout_2">
      <item row="0" column="0">
       <widget class="QLabel" name="label">
        <property name="sizePolicy">
         <sizepolicy hsizetype="Maximum" vsizetype="Preferred">
          <horstretch>0</horstretch>
          <verstretch>0</verstretch>
         </sizepolicy>
        </property>
        <property name="layoutDirection">
         <enum>Qt::LeftToRight</enum>
        </property>
        <property name="text">
         <string>Feature Image: </string>
        </property>
       </widget>
      </item>
      <item row="0" column="1">
       <widget class="QLabel" name="m_SelectedFeatureImageLabel">
        <property name="sizePolicy">
         <sizepolicy hsizetype="Minimum" vsizetype="Preferred">
          <horstretch>0</horstretch>
          <verstretch>0</verstretch>
         </sizepolicy>
        </property>
        <property name="text">
         <string>None</string>
        </property>
       </widget>
      </item>
      <item row="1" column="0">
       <widget class="QLabel" name="label_2">
        <property name="sizePolicy">
         <sizepolicy hsizetype="Maximum" vsizetype="Preferred">
          <horstretch>0</horstretch>
          <verstretch>0</verstretch>
         </sizepolicy>
        </property>
        <property name="text">
         <string>Mask:</string>
        </property>
       </widget>
      </item>
      <item row="1" column="1">
       <widget class="QLabel" name="m_SelectedMaskLabel">
        <property name="sizePolicy">
         <sizepolicy hsizetype="Minimum" vsizetype="Preferred">
          <horstretch>0</horstretch>
          <verstretch>0</verstretch>
         </sizepolicy>
        </property>
        <property name="text">
         <string>None</string>
        </property>
        <property name="indent">
         <number>-1</number>
        </property>
       </widget>
      </item>
      <item row="1" column="2">
       <widget class="QLabel" name="m_ErrorMessageLabel">
        <property name="sizePolicy">
         <sizepolicy hsizetype="Minimum" vsizetype="Preferred">
          <horstretch>0</horstretch>
          <verstretch>0</verstretch>
         </sizepolicy>
        </property>
        <property name="styleSheet">
         <string notr="true">color: rgb(255, 0, 0);</string>
        </property>
        <property name="text">
         <string>Error Message</string>
        </property>
        <property name="textFormat">
         <enum>Qt::AutoText</enum>
        </property>
        <property name="alignment">
         <set>Qt::AlignRight|Qt::AlignTrailing|Qt::AlignVCenter</set>
        </property>
       </widget>
      </item>
     </layout>
    </item>
    <item>
     <widget class="QCheckBox" name="m_IgnoreZerosCheckbox">
      <property name="text">
       <string>Ignore zero-valued voxels</string>
      </property>
     </widget>
    </item>
    <item>
     <widget class="QGroupBox" name="groupBox_statistics">
      <property name="enabled">
       <bool>false</bool>
      </property>
      <property name="title">
       <string>Statistics</string>
      </property>
      <layout class="QVBoxLayout" name="verticalLayout">
       <property name="leftMargin">
        <number>9</number>
       </property>
       <property name="rightMargin">
        <number>9</number>
       </property>
       <property name="bottomMargin">
        <number>9</number>
       </property>
       <item>
        <widget class="QTableWidget" name="m_StatisticsTable">
         <property name="minimumSize">
          <size>
           <width>100</width>
           <height>180</height>
          </size>
         </property>
         <property name="maximumSize">
          <size>
           <width>16777215</width>
           <height>16777215</height>
          </size>
         </property>
         <property name="verticalScrollBarPolicy">
          <enum>Qt::ScrollBarAsNeeded</enum>
         </property>
         <property name="horizontalScrollBarPolicy">
          <enum>Qt::ScrollBarAsNeeded</enum>
         </property>
         <property name="autoScroll">
          <bool>true</bool>
         </property>
         <property name="editTriggers">
          <set>QAbstractItemView::NoEditTriggers</set>
         </property>
         <property name="alternatingRowColors">
          <bool>true</bool>
         </property>
         <property name="showGrid">
          <bool>true</bool>
         </property>
         <property name="gridStyle">
          <enum>Qt::DotLine</enum>
         </property>
         <property name="cornerButtonEnabled">
          <bool>false</bool>
         </property>
         <property name="rowCount">
          <number>14</number>
         </property>
         <property name="columnCount">
          <number>1</number>
         </property>
         <attribute name="horizontalHeaderVisible">
          <bool>false</bool>
         </attribute>
         <attribute name="horizontalHeaderCascadingSectionResizes">
          <bool>false</bool>
         </attribute>
         <attribute name="horizontalHeaderDefaultSectionSize">
          <number>80</number>
         </attribute>
         <attribute name="horizontalHeaderHighlightSections">
          <bool>true</bool>
         </attribute>
         <attribute name="horizontalHeaderMinimumSectionSize">
          <number>80</number>
         </attribute>
         <attribute name="horizontalHeaderShowSortIndicator" stdset="0">
          <bool>false</bool>
         </attribute>
         <attribute name="horizontalHeaderStretchLastSection">
          <bool>true</bool>
         </attribute>
         <attribute name="verticalHeaderVisible">
          <bool>true</bool>
         </attribute>
         <attribute name="verticalHeaderCascadingSectionResizes">
          <bool>false</bool>
         </attribute>
         <attribute name="verticalHeaderDefaultSectionSize">
          <number>25</number>
         </attribute>
         <attribute name="verticalHeaderMinimumSectionSize">
          <number>25</number>
         </attribute>
         <attribute name="verticalHeaderShowSortIndicator" stdset="0">
          <bool>false</bool>
         </attribute>
         <attribute name="verticalHeaderStretchLastSection">
          <bool>false</bool>
         </attribute>
         <row>
          <property name="text">
           <string>Mean</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Median</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>StdDev</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>RMS</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Max</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Min</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>N</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>V (mm³)</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Skewness</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Kurtosis</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Uniformity</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>Entropy</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>MPP</string>
          </property>
         </row>
         <row>
          <property name="text">
           <string>UPP</string>
          </property>
         </row>
         <column>
          <property name="text">
           <string>0</string>
          </property>
         </column>
        </widget>
       </item>
       <item>
        <widget class="QWidget" name="widget" native="true">
         <layout class="QHBoxLayout" name="horizontalLayout">
          <property name="spacing">
           <number>0</number>
          </property>
          <property name="leftMargin">
           <number>0</number>
          </property>
          <property name="topMargin">
           <number>0</number>
          </property>
          <property name="rightMargin">
           <number>0</number>
          </property>
          <property name="bottomMargin">
           <number>0</number>
          </property>
          <item>
           <widget class="QPushButton" name="m_ButtonCopyStatisticsToClipboard">
            <property name="text">
             <string>Copy to Clipboard</string>
            </property>
           </widget>
          </item>
          <item>
           <spacer name="horizontalSpacer_3">
            <property name="orientation">
             <enum>Qt::Horizontal</enum>
            </property>
            <property name="sizeType">
             <enum>QSizePolicy::Fixed</enum>
            </property>
            <property name="sizeHint" stdset="0">
             <size>
              <width>20</width>
              <height>20</height>
             </size>
            </property>
           </spacer>
          </item>
          <item>
           <widget class="QCheckBox" name="m_CheckBox4dCompleteTable">
            <property name="enabled">
             <bool>false</bool>
            </property>
            <property name="text">
             <string>copy complete table</string>
            </property>
           </widget>
          </item>
          <item>
           <spacer name="horizontalSpacer">
            <property name="orientation">
             <enum>Qt::Horizontal</enum>
            </property>
            <property name="sizeHint" stdset="0">
             <size>
              <width>40</width>
              <height>20</height>
             </size>
            </property>
           </spacer>
          </item>
         </layout>
        </widget>
       </item>
      </layout>
     </widget>
    </item>
    <item>
     <widget class="QGroupBox" name="groupBox_histogram">
      <property name="enabled">
       <bool>false</bool>
      </property>
      <property name="minimumSize">
       <size>
        <width>400</width>
        <height>450</height>
       </size>
      </property>
      <property name="title">
       <string>Histogram</string>
      </property>
      <property name="checkable">
       <bool>false</bool>
      </property>
      <layout class="QVBoxLayout" name="verticalLayout_3">
+      <item>
+       <widget class="QLabel" name="label_HistogramIsInvisibleWarning">
+        <property name="enabled">
+         <bool>false</bool>
+        </property>
+        <property name="palette">
+         <palette>
+          <active>
+           <colorrole role="WindowText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="Text">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="ButtonText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+          </active>
+          <inactive>
+           <colorrole role="WindowText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="Text">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="ButtonText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>255</red>
+              <green>0</green>
+              <blue>0</blue>
+             </color>
+            </brush>
+           </colorrole>
+          </inactive>
+          <disabled>
+           <colorrole role="WindowText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>120</red>
+              <green>120</green>
+              <blue>120</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="Text">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>120</red>
+              <green>120</green>
+              <blue>120</blue>
+             </color>
+            </brush>
+           </colorrole>
+           <colorrole role="ButtonText">
+            <brush brushstyle="SolidPattern">
+             <color alpha="255">
+              <red>120</red>
+              <green>120</green>
+              <blue>120</blue>
+             </color>
+            </brush>
+           </colorrole>
+          </disabled>
+         </palette>
+        </property>
+        <property name="text">
+         <string/>
+        </property>
+       </widget>
+      </item>
       <item>
        <widget class="QGroupBox" name="groupBox_plot">
         <property name="enabled">
          <bool>false</bool>
         </property>
         <property name="sizePolicy">
          <sizepolicy hsizetype="Preferred" vsizetype="Preferred">
           <horstretch>0</horstretch>
           <verstretch>0</verstretch>
          </sizepolicy>
         </property>
         <property name="minimumSize">
          <size>
           <width>0</width>
           <height>0</height>
          </size>
         </property>
         <property name="maximumSize">
          <size>
           <width>16777215</width>
           <height>16777215</height>
          </size>
         </property>
         <property name="title">
          <string>Plot</string>
         </property>
         <layout class="QVBoxLayout" name="verticalLayout_2">
          <item>
           <layout class="QHBoxLayout" name="horizontalLayout_4">
            <item>
             <widget class="QRadioButton" name="m_barRadioButton">
              <property name="sizePolicy">
               <sizepolicy hsizetype="Preferred" vsizetype="Preferred">
                <horstretch>0</horstretch>
                <verstretch>0</verstretch>
               </sizepolicy>
              </property>
              <property name="styleSheet">
               <string notr="true"/>
              </property>
              <property name="text">
               <string>Barchart</string>
              </property>
              <property name="checked">
               <bool>true</bool>
              </property>
             </widget>
            </item>
            <item>
             <widget class="QRadioButton" name="m_lineRadioButton">
              <property name="sizePolicy">
               <sizepolicy hsizetype="Minimum" vsizetype="Minimum">
                <horstretch>0</horstretch>
                <verstretch>0</verstretch>
               </sizepolicy>
              </property>
              <property name="minimumSize">
               <size>
                <width>0</width>
                <height>0</height>
               </size>
              </property>
              <property name="text">
               <string>Linegraph</string>
              </property>
             </widget>
            </item>
            <item>
             <spacer name="horizontalSpacer_6">
              <property name="orientation">
               <enum>Qt::Horizontal</enum>
              </property>
              <property name="sizeHint" stdset="0">
               <size>
                <width>40</width>
                <height>20</height>
               </size>
              </property>
             </spacer>
            </item>
           </layout>
          </item>
          <item>
           <widget class="QCheckBox" name="m_ShowSubchartCheckBox">
            <property name="text">
             <string>Show Subchart</string>
            </property>
            <property name="checked">
             <bool>true</bool>
            </property>
           </widget>
          </item>
          <item>
           <widget class="QCheckBox" name="m_UseDefaultNBinsCheckBox">
            <property name="text">
             <string>Use default #bins</string>
            </property>
            <property name="checked">
             <bool>true</bool>
            </property>
           </widget>
          </item>
          <item>
           <widget class="QFrame" name="m_BinSizeFrame">
            <property name="frameShape">
             <enum>QFrame::NoFrame</enum>
            </property>
            <property name="frameShadow">
             <enum>QFrame::Raised</enum>
            </property>
            <layout class="QGridLayout" name="gridLayout">
             <property name="leftMargin">
              <number>0</number>
             </property>
             <property name="topMargin">
              <number>0</number>
             </property>
             <property name="rightMargin">
              <number>0</number>
             </property>
             <property name="bottomMargin">
              <number>0</number>
             </property>
             <property name="spacing">
              <number>0</number>
             </property>
             <item row="1" column="0">
              <widget class="QLabel" name="m_HistogramNBinsCaptionLabel">
               <property name="minimumSize">
                <size>
                 <width>60</width>
                 <height>0</height>
                </size>
               </property>
               <property name="maximumSize">
                <size>
                 <width>100</width>
                 <height>16777215</height>
                </size>
               </property>
               <property name="text">
                <string># bins:</string>
               </property>
              </widget>
             </item>
             <item row="1" column="1">
              <widget class="QSpinBox" name="m_HistogramNBinsSpinbox">
               <property name="enabled">
                <bool>false</bool>
               </property>
               <property name="toolTip">
                <string>Press enter to recalculate statistics with new bin size.</string>
               </property>
               <property name="minimum">
                <number>1</number>
               </property>
               <property name="maximum">
                <number>10000</number>
               </property>
               <property name="value">
                <number>100</number>
               </property>
              </widget>
             </item>
            </layout>
           </widget>
          </item>
         </layout>
        </widget>
       </item>
       <item>
        <widget class="QStackedWidget" name="m_StatisticsWidgetStack">
         <property name="minimumSize">
          <size>
           <width>0</width>
           <height>0</height>
          </size>
         </property>
         <property name="currentIndex">
          <number>0</number>
         </property>
         <widget class="QmitkChartWidget" name="m_JSHistogram">
          <property name="sizePolicy">
           <sizepolicy hsizetype="Preferred" vsizetype="Fixed">
            <horstretch>0</horstretch>
            <verstretch>0</verstretch>
           </sizepolicy>
          </property>
         </widget>
        </widget>
       </item>
       <item>
        <widget class="QLabel" name="m_InfoLabel">
         <property name="text">
          <string/>
         </property>
        </widget>
       </item>
       <item>
        <widget class="QWidget" name="widget_2" native="true">
         <layout class="QHBoxLayout" name="horizontalLayout_2">
          <property name="spacing">
           <number>0</number>
          </property>
          <property name="leftMargin">
           <number>0</number>
          </property>
          <property name="topMargin">
           <number>0</number>
          </property>
          <property name="rightMargin">
           <number>0</number>
          </property>
          <property name="bottomMargin">
           <number>0</number>
          </property>
          <item>
           <widget class="QPushButton" name="m_ButtonCopyHistogramToClipboard">
            <property name="sizePolicy">
             <sizepolicy hsizetype="Minimum" vsizetype="Fixed">
              <horstretch>0</horstretch>
              <verstretch>0</verstretch>
             </sizepolicy>
            </property>
            <property name="text">
             <string>Copy to Clipboard</string>
            </property>
           </widget>
          </item>
          <item>
           <spacer name="horizontalSpacer_2">
            <property name="orientation">
             <enum>Qt::Horizontal</enum>
            </property>
            <property name="sizeHint" stdset="0">
             <size>
              <width>40</width>
              <height>20</height>
             </size>
            </property>
           </spacer>
          </item>
         </layout>
        </widget>
       </item>
      </layout>
     </widget>
    </item>
    <item>
     <spacer name="verticalSpacer">
      <property name="orientation">
       <enum>Qt::Vertical</enum>
      </property>
      <property name="sizeHint" stdset="0">
       <size>
        <width>20</width>
        <height>40</height>
       </size>
      </property>
     </spacer>
    </item>
   </layout>
  </widget>
  <customwidgets>
   <customwidget>
    <class>QmitkChartWidget</class>
    <extends>QWidget</extends>
    <header location="global">QmitkChartWidget.h</header>
   </customwidget>
  </customwidgets>
  <resources/>
  <connections/>
 </ui>