diff --git a/CMake/mitkFunctionCheckCompilerFlags.cmake b/CMake/mitkFunctionCheckCompilerFlags.cmake
index 055bb8378a..8d9a18b3fb 100644
--- a/CMake/mitkFunctionCheckCompilerFlags.cmake
+++ b/CMake/mitkFunctionCheckCompilerFlags.cmake
@@ -1,40 +1,47 @@
 #
 # Helper macro allowing to check if the given flags are supported 
 # by the underlying build tool
 #
 # If the flag(s) is/are supported, they will be appended to the string identified by RESULT_VAR
 #
 # Usage:
 #   MITKFunctionCheckCompilerFlags(FLAGS_TO_CHECK VALID_FLAGS_VAR)
 #
 # Example:
 #
 #   set(myflags)
-#   MITKFunctionCheckCompilerFlags("-fprofile-arcs" myflags)
+#   mitkFunctionCheckCompilerFlags("-fprofile-arcs" myflags)
 #   message(1-myflags:${myflags})
-#   MITKFunctionCheckCompilerFlags("-fauto-bugfix" myflags)
+#   mitkFunctionCheckCompilerFlags("-fauto-bugfix" myflags)
 #   message(2-myflags:${myflags})
-#   MITKFunctionCheckCompilerFlags("-Wall" myflags)
+#   mitkFunctionCheckCompilerFlags("-Wall" myflags)
 #   message(1-myflags:${myflags})
 #
 #   The output will be:
 #    1-myflags: -fprofile-arcs
 #    2-myflags: -fprofile-arcs
 #    3-myflags: -fprofile-arcs -Wall
 
 INCLUDE(TestCXXAcceptsFlag)
 
 FUNCTION(mitkFunctionCheckCompilerFlags CXX_FLAG_TO_TEST RESULT_VAR)
   
   IF(CXX_FLAG_TO_TEST STREQUAL "")
     MESSAGE(FATAL_ERROR "CXX_FLAG_TO_TEST shouldn't be empty")
   ENDIF()
   
-  CHECK_CXX_ACCEPTS_FLAG(${CXX_FLAG_TO_TEST} HAS_FLAG)
+  # Internally, the macro CMAKE_CXX_ACCEPTS_FLAG calls TRY_COMPILE. To avoid
+  # the cost of compiling the test each time the project is configured, the variable set by
+  # the macro is added to the cache so that following invocation of the macro with
+  # the same variable name skip the compilation step.
+  # For that same reason, ctkFunctionCheckCompilerFlags function appends a unique suffix to
+  # the HAS_FLAG variable. This suffix is created using a 'clean version' of the flag to test.
+  STRING(REGEX REPLACE "-\\s\\$\\+\\*\\{\\}\\(\\)\\#" "" suffix ${CXX_FLAG_TO_TEST})
+  CHECK_CXX_ACCEPTS_FLAG(${CXX_FLAG_TO_TEST} HAS_FLAG_${suffix})
 
-  IF(HAS_FLAG)
+  IF(HAS_FLAG_${suffix})
     SET(${RESULT_VAR} "${${RESULT_VAR}} ${CXX_FLAG_TO_TEST}" PARENT_SCOPE)
   ENDIF()
 
 ENDFUNCTION()