diff --git a/CMake/BuildConfigurations/All.cmake b/CMake/BuildConfigurations/All.cmake
index 72f88a4792..4149d2e22c 100644
--- a/CMake/BuildConfigurations/All.cmake
+++ b/CMake/BuildConfigurations/All.cmake
@@ -1,57 +1,65 @@
 set(MITK_CONFIG_PACKAGES )
 
 set(_apple_package_excludes)
 
 if(APPLE)
   set(_apple_package_excludes
     SOFA
   )
 endif()
 
+set(_python_excludes )
+
+if(NOT (CMAKE_SIZEOF_VOID_P EQUAL 8) )
+  set(_python_excludes
+    Python
+    Numpy
+   )
+endif()
+
 set(_package_excludes
   ${_apple_package_excludes}
-  Python
-  Numpy
+  ${_python_excludes}
   OpenCL
   SYSTEM_Boost
   Boost_LIBRARIES
   SYSTEM_PYTHON
   SOFA_PLUGINS
   SOFA_PLUGINS_DIR
   SUPERBUILD
   BiophotonicsHardware_SpectroCam
 
   KWSTYLE
   MICROBIRD_TRACKER
   MICROBIRD_TRACKER_INCLUDE_DIR
   MICROBIRD_TRACKER_LIB
   MICRON_TRACKER
   OPTITRACK_TRACKER
   SPACENAVIGATOR
   TOF_KINECT
   TOF_KINECTV2
   TOF_MESASR4000
   TOF_PMDCAMBOARD
   TOF_PMDCAMCUBE
   TOF_PMDO3
   US_TELEMED_SDK
   videoInput
   WIIMOTE
 )
 
 get_cmake_property(_cache_vars CACHE_VARIABLES)
 foreach(_cache_var ${_cache_vars})
   string(REGEX REPLACE "MITK_USE_(.+)" "\\1" _package "${_cache_var}")
   if(_package AND NOT _package STREQUAL _cache_var)
     list(FIND _package_excludes ${_package} _index)
     if(_index EQUAL -1)
       list(APPEND MITK_CONFIG_PACKAGES ${_package})
     endif()
   endif()
 endforeach()
 
 set(MITK_BUILD_ALL_APPS ON CACHE BOOL "Build all MITK applications" FORCE)
 set(MITK_BUILD_ALL_PLUGINS ON CACHE BOOL "Build all MITK plugins" FORCE)
 set(MITK_BUILD_EXAMPLES ON CACHE BOOL "Build the MITK examples" FORCE)
 set(BLUEBERRY_BUILD_ALL_PLUGINS ON CACHE BOOL "Build all BlueBerry plugins" FORCE)
 set(BUILD_DiffusionMiniApps ON CACHE BOOL "Build MITK Diffusion MiniApps" FORCE)