diff --git a/CMakeExternals/ITK-4.5.1.patch b/CMakeExternals/ITK-4.5.1.patch
index 4b0e8506fa..4ce8bfe0c2 100644
--- a/CMakeExternals/ITK-4.5.1.patch
+++ b/CMakeExternals/ITK-4.5.1.patch
@@ -1,16 +1,28 @@
-diff -burN ITK-4.5.1/CMake/UseITK.cmake ITK-src/CMake/UseITK.cmake
+diff -burN ITK-4.5.1/CMake/UseITK.cmake ITK/CMake/UseITK.cmake
 --- ITK-4.5.1/CMake/UseITK.cmake	2014-02-28 19:46:45.000000000 +0100
-+++ ITK-src/CMake/UseITK.cmake	2015-01-13 12:51:44.513816520 +0100
-@@ -100,7 +101,11 @@
++++ ITK/CMake/UseITK.cmake	2015-01-29 14:31:00.137911666 +0100
+@@ -100,7 +100,11 @@
    unset(LIST_OF_FACTORY_NAMES)
  
    #-------------------
--  set_property(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS ITK_IO_FACTORY_REGISTER_MANAGER)
 +  if(NOT NO_DIRECTORY_SCOPED_ITK_COMPILE_DEFINITION)
 +    # We add a target scoped compile definition in MITK manually, to avoid leaking
 +    # the definition to other targets in the same directory or sub-directory.
-+    set_property(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS ITK_IO_FACTORY_REGISTER_MANAGER)
+   set_property(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS ITK_IO_FACTORY_REGISTER_MANAGER)
 +  endif()
    include_directories(BEFORE ${CMAKE_CURRENT_BINARY_DIR}/ITKIOFactoryRegistration)
  
  endif()
+diff -burN ITK-4.5.1/Modules/Core/Common/include/itkMetaDataObject.h ITK/Modules/Core/Common/include/itkMetaDataObject.h
+--- ITK-4.5.1/Modules/Core/Common/include/itkMetaDataObject.h	2014-02-28 19:46:45.000000000 +0100
++++ ITK/Modules/Core/Common/include/itkMetaDataObject.h	2015-01-29 18:28:24.625091845 +0100
+@@ -70,7 +70,7 @@
+  * \ingroup ITKCommon
+  */
+ template< typename MetaDataObjectType >
+-class MetaDataObject:public MetaDataObjectBase
++class ITKCommon_EXPORT MetaDataObject:public MetaDataObjectBase
+ {
+ public:
+   /** Smart pointer typedef support. */
+