diff --git a/Modules/SegmentationUI/Qmitk/QmitkTotalSegmentatorToolGUI.cpp b/Modules/SegmentationUI/Qmitk/QmitkTotalSegmentatorToolGUI.cpp
index 75e69621f6..6054177c0a 100644
--- a/Modules/SegmentationUI/Qmitk/QmitkTotalSegmentatorToolGUI.cpp
+++ b/Modules/SegmentationUI/Qmitk/QmitkTotalSegmentatorToolGUI.cpp
@@ -1,413 +1,413 @@
 #include "QmitkTotalSegmentatorToolGUI.h"
 
 #include "mitkProcessExecutor.h"
 #include "mitkTotalSegmentatorTool.h"
 #include <QApplication>
 #include <QDir>
 #include <QDirIterator>
 #include <QFileDialog>
 #include <QIcon>
 #include <QMessageBox>
 #include <QStandardPaths>
 #include <QUrl>
 #include <QtGlobal>
 
 MITK_TOOL_GUI_MACRO(MITKSEGMENTATIONUI_EXPORT, QmitkTotalSegmentatorToolGUI, "")
 
 QmitkTotalSegmentatorToolGUI::QmitkTotalSegmentatorToolGUI()
   : QmitkMultiLabelSegWithPreviewToolGUIBase(), m_SuperclassEnableConfirmSegBtnFnc(m_EnableConfirmSegBtnFnc)
 {
   // Nvidia-smi command returning zero doesn't always imply lack of GPUs.
   // Pytorch uses its own libraries to communicate to the GPUs. Hence, only a warning can be given.
   if (m_GpuLoader.GetGPUCount() == 0)
   {
     std::string warning = "WARNING: No GPUs were detected on your machine. The TotalSegmentator tool can be very slow.";
     this->ShowErrorMessage(warning);
   }
   m_EnableConfirmSegBtnFnc = [this](bool enabled)
   { return !m_FirstPreviewComputation ? m_SuperclassEnableConfirmSegBtnFnc(enabled) : false; };
 }
 
 void QmitkTotalSegmentatorToolGUI::ConnectNewTool(mitk::SegWithPreviewTool *newTool)
 {
   Superclass::ConnectNewTool(newTool);
   newTool->IsTimePointChangeAwareOff();
   m_FirstPreviewComputation = true;
 }
 
 void QmitkTotalSegmentatorToolGUI::InitializeUI(QBoxLayout *mainLayout)
 {
   m_Controls.setupUi(this);
   m_Controls.pythonEnvComboBox->addItem("Select");
   m_Controls.pythonEnvComboBox->setDuplicatesEnabled(false);
   m_Controls.previewButton->setDisabled(true);
   m_Controls.statusLabel->setTextFormat(Qt::RichText);
   m_Controls.subtaskComboBox->addItems(m_VALID_TASKS);
   this->AutoParsePythonPaths();
   this->SetGPUInfo();
   if (m_GpuLoader.GetGPUCount() != 0)
   {
     WriteStatusMessage(QString("<b>STATUS: </b><i>Welcome to Total Segmentator tool. You're in luck: " + QString::number(m_GpuLoader.GetGPUCount()) +
                                " GPU(s) were detected.</i>"));
   }
   else
   {
     WriteErrorMessage(QString("<b>STATUS: </b><i>Welcome to Total Segmentator tool. Sorry, " + QString::number(m_GpuLoader.GetGPUCount()) +
                               " GPUs were detected.</i>"));
   }
   mainLayout->addLayout(m_Controls.verticalLayout);
 
   connect(m_Controls.previewButton, SIGNAL(clicked()), this, SLOT(OnPreviewBtnClicked()));
   connect(m_Controls.installButton, SIGNAL(clicked()), this, SLOT(OnInstallBtnClicked()));
-  connect(m_Controls.pythonEnvComboBox,
-          SIGNAL(currentTextChanged(const QString &)),
-          this,
-          SLOT(OnPythonPathChanged(const QString &)));
+  // connect(m_Controls.pythonEnvComboBox,
+  //         SIGNAL(currentTextChanged(const QString &)),
+  //         this,
+  //         SLOT(OnPythonPathChanged(const QString &)));
 
   Superclass::InitializeUI(mainLayout);
 
   QString lastSelectedPyEnv = m_Settings.value("TotalSeg/LastPythonPath").toString();
   m_Controls.pythonEnvComboBox->insertItem(0, lastSelectedPyEnv);
 
   const QString storageDir = QStandardPaths::writableLocation(QStandardPaths::GenericDataLocation) + QDir::separator() +
                              qApp->organizationName() + QDir::separator() + m_VENV_NAME;
-  MITK_INFO << storageDir.toStdString();
   m_IsInstalled = this->IsTotalSegmentatorInstalled(storageDir);
   if (m_IsInstalled)
   {
+    OnPythonPathChanged(storageDir);
     this->EnableAll(m_IsInstalled);
-    m_PythonPath = storageDir;
   }
 }
 
 void QmitkTotalSegmentatorToolGUI::EnableWidgets(bool enabled)
 {
   Superclass::EnableWidgets(enabled);
 }
 
 void QmitkTotalSegmentatorToolGUI::SetGPUInfo()
 {
   std::vector<QmitkGPUSpec> specs = m_GpuLoader.GetAllGPUSpecs();
   for (const QmitkGPUSpec &gpuSpec : specs)
   {
     m_Controls.gpuComboBox->addItem(QString::number(gpuSpec.id) + ": " + gpuSpec.name + " (" + gpuSpec.memory + ")");
   }
   if (specs.empty())
   {
     m_Controls.gpuComboBox->setEditable(true);
     m_Controls.gpuComboBox->addItem(QString::number(0));
     m_Controls.gpuComboBox->setValidator(new QIntValidator(0, 999, this));
   }
 }
 
 unsigned int QmitkTotalSegmentatorToolGUI::FetchSelectedGPUFromUI()
 {
   QString gpuInfo = m_Controls.gpuComboBox->currentText();
   if (m_GpuLoader.GetGPUCount() == 0)
   {
     return static_cast<unsigned int>(gpuInfo.toInt());
   }
   else
   {
     QString gpuId = gpuInfo.split(":", QString::SplitBehavior::SkipEmptyParts).first();
     return static_cast<unsigned int>(gpuId.toInt());
   }
 }
 
 //namespace
 //{
 //  void onPythonProcessEvent(itk::Object * /*pCaller*/, const itk::EventObject &e, void *)
 //  {
 //    std::string testCOUT;
 //    std::string testCERR;
 //    const auto *pEvent = dynamic_cast<const mitk::ExternalProcessStdOutEvent *>(&e);
 //
 //    if (pEvent)
 //    {
 //      testCOUT = testCOUT + pEvent->GetOutput();
 //      MITK_INFO << testCOUT;
 //    }
 //
 //    const auto *pErrEvent = dynamic_cast<const mitk::ExternalProcessStdErrEvent *>(&e);
 //
 //    if (pErrEvent)
 //    {
 //      testCERR = testCERR + pErrEvent->GetOutput();
 //      MITK_ERROR << testCERR;
 //    }
 //  }
 //} // namespace
 
 void QmitkTotalSegmentatorToolGUI::EnableAll(bool isEnable) 
 {
   m_Controls.previewButton->setEnabled(isEnable);
   m_Controls.subtaskComboBox->setEnabled(isEnable);
   m_Controls.installButton->setEnabled((!isEnable));
 }
 
 void QmitkTotalSegmentatorToolGUI::OnInstallBtnClicked()
 {
   const QString storageDir = QStandardPaths::writableLocation(QStandardPaths::GenericDataLocation) + QDir::separator() +
                              qApp->organizationName() + QDir::separator();
   MITK_INFO << storageDir.toStdString();
 
   bool isInstalled = false;
 #ifndef _WIN32
   isInstalled = SetUpTotalSegmentator(storageDir);
 #endif
   if (isInstalled)
   {
-    m_PythonPath = storageDir + m_VENV_NAME;
+    const QString pythonPath = storageDir + m_VENV_NAME;
+    OnPythonPathChanged(pythonPath);
     this->WriteStatusMessage("Successfully installed TotalSegmentator");
   }
   else
   {
     this->WriteErrorMessage("Couldn't find TotalSegmentator");
   }
   this->EnableAll(isInstalled);
 }
 
 
 bool QmitkTotalSegmentatorToolGUI::SetUpTotalSegmentatorWIN(const QString & /*path*/)
 {
   return false;
 }
 
 
 bool QmitkTotalSegmentatorToolGUI::SetUpTotalSegmentator(const QString &path)
 {
   auto tool = this->GetConnectedToolAs<mitk::TotalSegmentatorTool>();
   if (nullptr == tool)
   {
     return false;
   }
   bool isInstalled = false;
   QDir folderPath(path);
   if (this->IsTotalSegmentatorInstalled(folderPath.absoluteFilePath(m_VENV_NAME)))
   {
     return true;
   }
   folderPath.mkdir(m_VENV_NAME);
   if (!folderPath.cd(m_VENV_NAME))
   {
     return false; // Check if directory creation was successful.
   }
   mitk::ProcessExecutor::ArgumentListType args;
   auto spExec = mitk::ProcessExecutor::New();
   auto spCommand = itk::CStyleCommand::New();
   spCommand->SetCallback(tool->onPythonProcessEvent);
   spExec->AddObserver(mitk::ExternalProcessOutputEvent(), spCommand);
 
   args.push_back("-m"); 
   args.push_back("venv");
   args.push_back(m_VENV_NAME.toStdString());
   spExec->Execute(path.toStdString(), "/usr/bin/python3", args);// Setup local virtual environment
 
   if (folderPath.cd("bin"))
   {
     std::string workingDir;
     workingDir = folderPath.absolutePath().toStdString();
     args.clear();
     args.push_back("install");
     args.push_back("Totalsegmentator==" + m_TOTALSEGMENTATOR_VERSION);
     spExec->Execute(workingDir, "pip3", args); // Install TotalSegmentator in it.
     if (this->IsTotalSegmentatorInstalled(folderPath.absolutePath())) 
     {
       isInstalled = true; // Check if installation was successful
     }
     args.clear();
     args.push_back("-c");
     std::string pythonCode; // python syntax to check if torch is installed with CUDA.
     pythonCode.append("import torch;");
     pythonCode.append("print('Pytorch installed with CUDA') if torch.cuda.is_available else ValueError('PyTorch installed without CUDA');");
     args.push_back(pythonCode);
     spExec->Execute(workingDir, "python3", args);
   }
   return isInstalled;
 }
 
 void QmitkTotalSegmentatorToolGUI::OnPreviewBtnClicked()
 {
   auto tool = this->GetConnectedToolAs<mitk::TotalSegmentatorTool>();
   if (nullptr == tool)
   {
     return;
   }
   QString pythonPathTextItem = "";
   try
   {
     m_Controls.previewButton->setEnabled(false);
     qApp->processEvents();
     if (!this->IsTotalSegmentatorInstalled(m_PythonPath))
     {
       throw std::runtime_error(m_WARNING_TOTALSEG_NOT_FOUND);
     }
     //pythonPathTextItem = m_Controls.pythonEnvComboBox->currentText();
     bool isFast = m_Controls.fastBox->isChecked();
     QString subTask = m_Controls.subtaskComboBox->currentText();
     if (subTask != m_VALID_TASKS[0])
     {
       isFast = true;
     }
     tool->SetPythonPath(m_PythonPath.toStdString());
     tool->SetGpuId(FetchSelectedGPUFromUI());
     tool->SetFast(isFast);
     tool->SetSubTask(subTask.toStdString());
     this->WriteStatusMessage(QString("<b>STATUS: </b><i>Starting Segmentation task... This might take a while.</i>"));
     tool->UpdatePreview();
     m_Controls.previewButton->setEnabled(true);
   }
   catch (const std::exception &e)
   {
     std::stringstream errorMsg;
     errorMsg << "<b>STATUS: </b>Error while processing parameters for TotalSegmentator segmentation. Reason: "
              << e.what();
     this->ShowErrorMessage(errorMsg.str());
     this->WriteErrorMessage(QString::fromStdString(errorMsg.str()));
     m_Controls.previewButton->setEnabled(true);
     return;
   }
   catch (...)
   {
     std::string errorMsg = "Unkown error occured while generation TotalSegmentator segmentation.";
     this->ShowErrorMessage(errorMsg);
     m_Controls.previewButton->setEnabled(true);
     return;
   }
   this->SetLabelSetPreview(tool->GetPreviewSegmentation());
   tool->IsTimePointChangeAwareOn();
   this->ActualizePreviewLabelVisibility();
   this->WriteStatusMessage("<b>STATUS: </b><i>Segmentation task finished successfully.</i>");
   if (!pythonPathTextItem.isEmpty())// only cache if the prediction ended without errors.
   { 
     QString lastSelectedPyEnv = m_Settings.value("TotalSeg/LastPythonPath").toString();
     if (lastSelectedPyEnv != pythonPathTextItem) 
     {
       m_Settings.setValue("TotalSeg/LastPythonPath", pythonPathTextItem);
     }
   }
 }
 
 void QmitkTotalSegmentatorToolGUI::ShowErrorMessage(const std::string &message, QMessageBox::Icon icon)
 {
   this->setCursor(Qt::ArrowCursor);
   QMessageBox *messageBox = new QMessageBox(icon, nullptr, message.c_str());
   messageBox->exec();
   delete messageBox;
   MITK_WARN << message;
 }
 
 void QmitkTotalSegmentatorToolGUI::WriteStatusMessage(const QString &message)
 {
   m_Controls.statusLabel->setText(message);
   m_Controls.statusLabel->setStyleSheet("font-weight: bold; color: white");
 }
 
 void QmitkTotalSegmentatorToolGUI::WriteErrorMessage(const QString &message)
 {
   m_Controls.statusLabel->setText(message);
   m_Controls.statusLabel->setStyleSheet("font-weight: bold; color: red");
 }
 
 bool QmitkTotalSegmentatorToolGUI::IsTotalSegmentatorInstalled(const QString &pythonPath)
 {
   QString fullPath = pythonPath;
 #ifdef _WIN32
   if (!(fullPath.endsWith("Scripts", Qt::CaseInsensitive) || fullPath.endsWith("Scripts/", Qt::CaseInsensitive)))
   {
     fullPath += QDir::separator() + QString("Scripts");
   }
 #else
   if (!(fullPath.endsWith("bin", Qt::CaseInsensitive) || fullPath.endsWith("bin/", Qt::CaseInsensitive)))
   {
     fullPath += QDir::separator() + QString("bin");
   }
 #endif
   fullPath = fullPath.mid(fullPath.indexOf(" ") + 1);
   bool isExists = QFile::exists(fullPath + QDir::separator() + QString("TotalSegmentator")) &&
 #ifdef _WIN32
                   QFile::exists(fullPath + QDir::separator() + QString("python.exe"));
 #else
                   QFile::exists(fullPath + QDir::separator() + QString("python3"));
 #endif
   return isExists;
 }
 
 void QmitkTotalSegmentatorToolGUI::AutoParsePythonPaths()
 {
   QString homeDir = QDir::homePath();
   std::vector<QString> searchDirs;
 #ifdef _WIN32
   searchDirs.push_back(QString("C:") + QDir::separator() + QString("ProgramData") + QDir::separator() +
                        QString("anaconda3"));
 #else
   // Add search locations for possible standard python paths here
   searchDirs.push_back(homeDir + QDir::separator() + "environments");
   searchDirs.push_back(homeDir + QDir::separator() + "anaconda3");
   searchDirs.push_back(homeDir + QDir::separator() + "miniconda3");
   searchDirs.push_back(homeDir + QDir::separator() + "opt" + QDir::separator() + "miniconda3");
   searchDirs.push_back(homeDir + QDir::separator() + "opt" + QDir::separator() + "anaconda3");
 #endif
   for (QString searchDir : searchDirs)
   {
     if (searchDir.endsWith("anaconda3", Qt::CaseInsensitive))
     {
       if (QDir(searchDir).exists())
       {
         m_Controls.pythonEnvComboBox->insertItem(0, "(base): " + searchDir);
         searchDir.append((QDir::separator() + QString("envs")));
       }
     }
     for (QDirIterator subIt(searchDir, QDir::AllDirs, QDirIterator::NoIteratorFlags); subIt.hasNext();)
     {
       subIt.next();
       QString envName = subIt.fileName();
       if (!envName.startsWith('.')) // Filter out irrelevent hidden folders, if any.
       {
         m_Controls.pythonEnvComboBox->insertItem(0, "(" + envName + "): " + subIt.filePath());
       }
     }
   }
   m_Controls.pythonEnvComboBox->setCurrentIndex(-1);
 }
 
 void QmitkTotalSegmentatorToolGUI::OnPythonPathChanged(const QString &pyEnv)
 {
   if (pyEnv == QString("Select"))
   {
     QString path =
       QFileDialog::getExistingDirectory(m_Controls.pythonEnvComboBox->parentWidget(), "Python Path", "dir");
     if (!path.isEmpty())
     {
       this->OnPythonPathChanged(path);                                  // recall same function for new path validation
       bool oldState = m_Controls.pythonEnvComboBox->blockSignals(true); // block signal firing while inserting item
       m_Controls.pythonEnvComboBox->insertItem(0, path);
       m_Controls.pythonEnvComboBox->setCurrentIndex(0);
       m_Controls.pythonEnvComboBox->blockSignals(
         oldState); // unblock signal firing after inserting item. Remove this after Qt6 migration
     }
   }
   else if (!this->IsTotalSegmentatorInstalled(pyEnv))
   {
     this->ShowErrorMessage(m_WARNING_TOTALSEG_NOT_FOUND);
     m_Controls.previewButton->setDisabled(true);
   }
   else
   {
     // Show positive status meeage
     m_Controls.previewButton->setDisabled(false);
     m_PythonPath = pyEnv.mid(pyEnv.indexOf(" ") + 1);
 #ifdef _WIN32
     if (!(m_PythonPath.endsWith("Scripts", Qt::CaseInsensitive) ||
           m_PythonPath.endsWith("Scripts/", Qt::CaseInsensitive)))
     {
       m_PythonPath += QDir::separator() + QString("Scripts");
     }
 #else
     if (!(m_PythonPath.endsWith("bin", Qt::CaseInsensitive) || m_PythonPath.endsWith("bin/", Qt::CaseInsensitive)))
     {
       m_PythonPath += QDir::separator() + QString("bin");
     }
 #endif
   }
 }