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Maniphest T27350

Refactoring of T1 map calculation/selection for perfusion and CEST
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Description

In perfusion image analysis, conversion from signal to concentration can be done using a native T1-map. Currently, this is only done in the DCE Perfusion Datafit View using the variable flip angle method, which is just one specific method to obtain T1-Maps. See also related task https://phabricator.mitk.org/T27047.

T1-Maps are generated as well in the CEST context, so this might be combined into one functionality.

In this task, a refactoring strategy is developed, which includes perfusion and CEST applications.

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Event Timeline

kompan triaged this task as Normal priority.Apr 23 2020, 12:29 PM
kompan created this task.
kislinsk moved this task from Backlog to Perfusion on the MITK (v2021.02) board.Apr 24 2020, 7:41 AM
kompan added a project: Cleared.May 13 2020, 10:21 AM
floca edited projects, added Next Milestone; removed MITK (v2021.02).Sep 10 2020, 4:35 PM
kislinsk added a project: MITK.Sep 10 2020, 5:38 PM
kislinsk edited projects, added MITK (v2022.04); removed MITK, Next Milestone.Nov 16 2021, 9:23 AM
kislinsk edited projects, added Next Milestone, MITK; removed MITK (v2022.04).Apr 29 2022, 1:38 PM
kislinsk edited projects, added MITK (v2023.12); removed MITK, Next Milestone.May 17 2023, 2:57 PM
kompan mentioned this in T27339: Provide public MITK ModelFit installer on a regular basis.Sep 11 2023, 7:38 AM
kompan removed a project: Cleared.
kompan removed a subscriber: kompan.
kislinsk edited projects, added MITK (v2024.06); removed MITK (v2023.12).Dec 5 2023, 10:38 AM
kompan closed this task as Wontfix.Feb 26 2024, 11:33 AM
kompan claimed this task.

I looked into the issue in more detail and found that the current implementation of the variable flip angle T_1-mapping cannot be easily replaced with a more general T_1-mapping approach. The reason for this is that not just the T_1-map is calculated but also the signal scaling factor S_0 is determined (which is additionally required for the conversion).

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