If you start region growing on a sagittal plane, and continue region growing on a coronal plane by performing the region growing with maximal regional expansion parameters, then you can choose a seed point in the grown area and minimize the region growing parameters afterwards, thus modifying the first region growing result again, which should be no proper behaviour.
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The bug is almost not reproducible, it happens only if the modification of the maximal region happens immediately after releasing the mouse button ( held clicked for the region expansion ).
However it can be more easy reproduced on large datasets, so it could be some timing problems.
But the use-case is really seldom (selecting a complete large slice with a region-growing tool), setting to WONTFIX