When the segmentation view is displayed then the node selection in the data manager behaves in a weird way.
If a node is selected and made visible (its checkbox is on) then if you click on another node's name, the previously selected image will not visible (checkbox off) and the new image will be visible. (Although you did not click in the checkbox, just on the name.)
However, if in the same situation you click inside of the checkbox of the other node (to make it visible), then the checkbox gets on for a moment and becomes off right after immediately. To turn it on, you have to click into the checkbox again.
I think, the intention behind this is that the segmentation view can work only with one reference image. The problem is that this happens even if you work in another view but accidentally the segmentation view is shown. (For a while I did not realize that this double clicking is needed because of the segmentation view.)
It would be much better to disable the Reference image combo and/or the tool buttons if the set of selection is not suitable. Also a message could be shown in the view.