As was pointed out by a physician, MITKs scrolling direction is inverted when compared to other viewers, like e.g. a PACS workstation:
Moving the mouse down in scrolling mode will actually scroll up in the slice stack (move towards the head), moving the mouse away from the user will scroll towards the 'feet' of the 'patient'.
In order to improve acceptance by medical users, the scrolling direction should be inverted.