The first colour in a lookup table is hardcoded to be transparent.
https://github.com/MITK/MITK/blob/master/Core/Code/Rendering/mitkImageVtkMapper2D.cpp#L1144
https://github.com/MITK/MITK/blob/master/Core/Code/Rendering/mitkImageVtkMapper2D.cpp#L675
This is OK if the background is black. When a given data value is mapped to transparent, and the background of the rendered scene is white, you can see the background white colour through the image.
Please can we add an opacity property that defaults to zero (for minimal impact) that can be set 0-1 to control the opacity.